Nucleotides Flashcards
(24 cards)
Structure of nucleotides
Pentose, base, phosphates
Pyrimidines
C, T, U
Purines
A and G
DNA
Anti parallel
Mutations
Spontaneous, external factors, chemicals
External factor mutations
Physical factors: uv radiation, ionizing radiation (x and gamma rays)
Chemical mutations
Deaminating and oxidative agents
Transcription
DNA TO RNA
Translation
RNA TO PROTEINS
Genome
Set of chromosomes
Chromosome
Grouping of DNA with many genes
Gene
Segment of DNA that encodes information
Cell cycle
Mitosis, g1, s, g2
Exons
Coding segments
Introns
Non coding segments
3 rules of DNA replication
Semiconservative, bidirectional, 5’ to 3’
Transcription location and enzyme
Nucleus and RNA polymerase
Translation 3 components and location
Ribosome, genetic code, tRNA….. cytoplasm
Aminoacetyl-tRNA synthases
Loads amino acids with corresponding anticodons
Point mutations
Silent, nonsense, missense
Frameshift mutations
Insertion and deletions
Silent
Same amino acids, no effect
Nonsense
Changes size of polypeptide
Missense
Leads to a different amino acid