nucleotides and phosphodiester bonds Flashcards

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1
Q

what are nucleotides?

A

many repeating units (monomers) in the nucleic acids

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2
Q

what three things are nucleotides formed from?

A
  • a pentose sugar
  • a nitrogenous base
  • a phosphate group
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3
Q

give the three components of a DNA nucleotide:

A
  • a deoxyribose sugar with the hydrogen group at position 2’
  • one of four nitrogenous bases
  • a phosphate group
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4
Q

give the three components of an RNA nucleotide:

A
  • a ribose sugar with an OH group at position 2’
  • one of four nitrogenous bases
  • a phosphate group
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5
Q

give the four nitrogenous bases in DNA:

A
  • Adenine (A)
  • Thymine (T)
  • Cytosine (C)
  • Guanine (G)
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6
Q

give the four nitrogenous bases in RNA:

A
  • Adenine (A)
  • Uracil (U)
  • Cytosine (C)
  • Guanine (G)
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7
Q

what does the presence of the hydroxyl group do for RNA?

A

makes RNA more susceptible to hydrolysis, hence why it is used as the transport molecule, rather than the storage molecule (DNA)

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8
Q

what are pyrimidines?

A

nitrogenous bases that have a single ring structure

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9
Q

what are purines?

A

nitrogenous bases that have a double ring structure

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10
Q

what three bases are pyrimidines?

A
  • Cytosine
  • Thymine
  • Uracil
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11
Q

what two bases are purines?

A
  • Adenine
  • Guanine
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12
Q

Is DNA or RNA single stranded?

A

RNA

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13
Q

how is a phosphodiester bond formed?

A

through the condensation reaction between two nucleotides

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14
Q

what is a polynucleotide?

A

substances made up of many nucleotides joined together in long chains

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15
Q

where does the condensation reaction occur?

A

between the phosphate group of one nucleotide and the pentose sugar of the next molecule

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16
Q

why is it called a phosphodiester bond?

A

because it contains a phosphate group and TWO ester bonds

17
Q

what is the sugar-phosphate backbone?

A

the chain of alternating phosphate groups and pentose sugars produced as a result of the phosphodiester bonds

18
Q

how do you break down a polynucleotide?

A

the phosphodiester bonds must be broken and a water molecule added (hydrolysis reaction)