Nutrition Flashcards
(40 cards)
Why do we need vitamins and minerals?
They are essential for life – they don’t provide energy but are necessary in small amounts for life and growth
Which processes are vitamins and minerals involved in?
They act as “chemical partners” with key roles in lots of vital processes including:
• Metabolism
• Cell production
• Tissue repair
Who discovered vitamins?
Casmir Funk = biochemist born in Poland, moved to London in 1910
Name all the water soluble vitamins (9)
- Vitamin C (Ascorbic acid)
- Vitamin B1 (thiamine)
- Vitamin B2 (riboflavin)
- Vitamin B3 (niacin)
- Vitamin B5 (pantothenic acid)
- Vitamin B6 (pyridoxine)
- Vitamin B7 (biotin)
- Vitamin B9 (folate/folic acid)
- Vitamin B12 (cobalamin)
There are nine water soluble vitamins (excreted) – eight B vitamins and vitamin c
What is folate
Folate is the “natural” form of vitamin b9. It is added to foods/as a supplement as folic acid (better absorbed than that from food source)
Where are most water soluble vitamins absorbed and what is the exception
- Most water soluble vitamins absorbed in upper small intestine (duodenum) except for vitamin B12
- Vitamin B12 absorbed in ileum – binds to intrinsic factor (protein secreted by stomach). Resulting complex is absorbed across the ileal mucosa.
What are the key facts surrounding how water-soluble vitamins are absorbed and stored?
Absorption of water-soluble vitamins is rapid. Vitamin b12 and folate (b9) absorption occurs independently from sodium but the seven remaining water-soluble vitamins absorbed by carriers that are sodium cotransporters. Water soluble vitamins are not stored
Name the 4 main fat soluble vitamins
- Vitamin A
- Vitamin D
- Vitamin E (tocopheryl)
- Vitamin K
Name the vitamin D and vitamin K derivatives
Vitamin D - includes ergocalciferol (calciferol, vitamin D2), colecalciferol (vitamin D3), dihydrotachysterol, alfacalcidol (1α-hydroxycholecalciferol), and calcitriol (1,25-dihydroxycholecalciferol). Vitamin K (phytomenadione)
Why do we need vitamin K
Vitamin K is necessary for the production of blood clotting factors and proteins necessary for the normal calcification of bone
Where are fat soluble vitamins absorbed and when might this be reduced
Fat soluble vitamins absorbed by bile in large intestine and can be reduced if fat absorption is decreased e.g. by lack of pancreatic enzymes/low fat diet. These vitamins can be stored
How do humans synthesise vitamins d and k
Vitamin K – many subtypes produced by GI flora from original plant sources then absorbed (Think warfarin, antibiotics, decreased INR)
Vitamin D – dietary but also synthesised in skin via cholesterol by sunlight
What can deficiency of vitamin A be associated with
Eye defects (particularly xerophthalmia), increased infection risk. Rare in UK
What can deficiency of vitamin B (not B12) be associated with and how do we treat it
B1 – tiredness, poor appetite, weight loss, GI problems. B2 – sight loss, sore mouth B3 – tremors, GI problems, skin abnormality. B5 – heart and GI issues. B6- depression, vomiting, anaemia. B7 – skin inflammation, conjunctivitis. B9 (folic acid) - anaemia, GI disorders, palpitations.
Treatment - thiamine (B1), riboflavin (B2), and nicotinamide. In severe deficiency - treated initially by the parenteral administration of B vitamins (Pabrinex®), followed by oral administration of thiamine
What can deficiency of vitamin C be associated with
Scurvy. ‘Vitamin C therapy is essential in scurvy, but less florid manifestations of vitamin C deficiency are commonly found, especially in the elderly. Severe scurvy causes gingival swelling and bleeding margins as well as petechiae on the skin.’
What are minerals?
Inorganic substances. Minerals are required in large amounts while trace elements are only required in smaller quantities
What does the body need minerals for
Variety of functions including
Formation of bones and teeth, Essential constituents of body fluids, tissues and blood, Components of enzyme systems, Nerve function
Give examples of minerals
- Calcium
- Sodium
- Magnesium
- Potassium
- Chloride
- Phosphorus
- Iron
- Iodine
- Selenium
- Zinc
- Copper
Where do we get minerals from and what affects their absorption
Food and supplements (however, no one food provides all minerals). This is why we need healthy balanced diet. Water is also a source
Absorption may be affected by:
- Presence of other minerals/vitamins
- Components found in food
- Amount of mineral already in body
Give some examples of common mineral deficiencies and what affects they can cause
- Potassium and Magnesium - cardiac arrhythmias
- Calcium and Magnesium - osteoporosis
- Calcium and Magnesium - muscle cramps and tetany
- Zinc - hair loss and poor wound healing
- Iron – anaemia
- Copper - Wilson’s disease
Where are the nutrition guidelines derived from
National Diet and Nutrition Survey (NDSD) and the Scientific Advisory Committee on Nutrition (SACN) who advises government on diet and health
What are RNIs, LRNIs and EARs
Reference Nutrient Intakes (RNIs)
Lower Reference Nutrient Intakes (LRNIs)
Estimated Average Requirements (EARs)
Define the Estimated Average Requirements (EARs).
The EAR is an estimate of the average requirement of energy or a nutrient needed by a group of people (i.e. approximately 50% of people will require less, and 50% will require more)