nutrition Flashcards
(34 cards)
what is Hans-benedict equation
weight height age
what is physical activity level (PAL)
total energy expenditure/basal metabolic rate
what is METs
energy expenditure/sitting quietly
compendium of METs
energy balance= ?
energy intake - energy expenditure
issues with energy intake- energy expenditure
hunter gatherer are more active, but expend the same energy to people in industrialised societies
hormones like insulin and glucagon also play a role, certain foods satiate you more than others
what is energy density
energy per unit mass
relevance: energy dense foods can contribute to adiposity, weight gain
high fibre foods and high water without increasing the calories
what is a nutrient
any chemical substance that is obtained from food and used in the body for metabolic processes
what are the macronutrients
carbohydrates
lipids
proteins
what are micronutrients
vitamins
minerals
how many vitamins are there
13
what are the fat soluble vitamins
ADEK
likely to be toxic if supplemented
where are the vitamins ADEK stored
within cells associated with fat
what are the water soluble vitamins
9 of them
C and B group
difference between water soluble and fat soluble vitamins
water soluble vitamins are easily excreted whereas fat soluble vitamins are not readily exerted
water soluble vitamins are easy to be in a deficit whereas fat soluble vitamins are more likely to reach toxic levels if supplemented\
water soluble vitamins circulate freely in fluid compartments of the body whereas fat soluble vitamins are stored within the fat associated cells
what are minerals
include macrominerals
eg.
Ca, P, Mg, Na, K, Cl, and S - you require approx. 100mg/day
eg.Trace minerals include Fe, Zn, Cu, Se, I, Cr, F, Mn, Mb
where is iron absorbed
in the duodenum of the small intestine
Iron in our foods, and eventually in our cells as well, is normally found in a 3+ oxidation state (“ferric iron”, “ferritin”) but iron in this state cannot be absorbed.
how do we solve this issue?
Vitamin C in the membrane protein vitamin C ferrireductase helps to reduce iron into 2+ state, enabling transport of iron via the apical membrane of the enterocyte.
what happens to excess iron
Excess iron is transported to the liver and stored as ferritin.
Small amounts of ferritin are secreted into the blood.
where is vitamin D produced
Vitamin D is produced in the skin and absorbed from food in a non-bioactive form.
what is vitamin D converted into
Vitamin D must first be converted into 25-dihydroxyvitamin D in the liver, before further activation in the kidney to form 1, 25-dihydroxyvitamin D, also known as calcitriol.
what is calcitriol ( 25-dihydroxyvitamin D) important for
3 reasons
Calcitriol is important to calcium metabolism (and consequently bone health) as it:
Enables intestinal absorption of Ca2+ and PO42-
Promotes resorption of bone by osteoclasts
Facilitates renal reabsorption of Ca2+ and PO42-
what do parietal cells secrete
HCL and intrinsic factor
what is the importance in intrinsic factor in vitamin B12
B12 is bound to intrinsic factor in the stomach which is necessary for B12 absorption which takes place in the terminal ileum.
how does autoimmune gastritis/ pernicious anaemia cause B12 deficiency
Pernicious anaemia / autoimmune gastritis reduces secretion of intrinsic factor, leading to B12 deficiency.