Nystagmus Flashcards

(36 cards)

1
Q

What is the definition of nystagmus?

A

Pathological or physiological rhythmic oscillation of the eyes - stops during sleep, usually bilateral.

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2
Q

What do you need to describe when assessing a patient with nystagmus?

A

Rhythm/waveform
Direction (if jerky)
Frequency/velocity
Amplitude
Oscillopsia
Null point

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3
Q

What are the types of physiological nystagmus?

A

End point
Post rotational
Induced by caloric testing
Optokinetic

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4
Q

What is end point nystagmus?

A

Jerky nystagmus observed when looking in extreme gazes, lasts a few seconds

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5
Q

What is post rotational nystagmus?

A

Occurs after stopping rapid rotation of the body.
Large amplitude, slow frequency, opposite direction to rotation

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6
Q

What is optokinetic nystagmus?

A

Occurs when a target is being followed.
Slow phase while following target, then fast phase to reset to fixate on next target.
(train/car window examples)

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7
Q

What is ‘induced by caloric testing’ nystagmus?

A

Test which investigates balancing mechanisms of inner ear induces nystagmus. Cold and warm water put into ear.
COWS: Cold stimulates fast phase Opposite to stimulated ear, Warm stimulates fast phase Same side to stimulated ear.

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8
Q

How can pathological nystagmus be classified?

A

Time of onset (congenital vs acquired)
Waveform (jerky vs pendular)
Cause (cerebellar vs labyrinthine)

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9
Q

What are the types of congenital nystagmus?

A

Low vision
Idiopathic
Latent
Manifest latent
Spasmus Nutans

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10
Q

What is low vision nystagmus?

A

Occurs secondary to poor vision (congenital or develops during plastic period)

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11
Q

What are some common causes of low vision nystagmus?

A

Corneal scarring
Dense cataracts
Infantile glaucoma
Ocular albinism
Optic nerve hypoplasia
Optic atrophy
Macular hypoplasia

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12
Q

What is congenital idiopathic nystagmus?

A

Covers all manifest jerky nystagmus types present from birth/soon after with no visual defect

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13
Q

What is latent nystagmus?

A

Only present when BSV not possible

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14
Q

What is manifest latent nystagmus?

A

Manifest with both eyes open
Amplitude increases if one eye occluded

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15
Q

What is Spasmus Nutans?

A

Nystagmus, AHP and involuntary head movements present

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16
Q

What are the types of acquired nystagmus?

A

Labyrinth disease
Central vestibular disease
Cerebellar disease
Gaze evoked
Convergence retraction
Dissociated
See-saw

17
Q

What are the features of nystagmus caused by labyrinth disease?

A

Horizontal jerk
Fast phase opposite side to disease
Amplitude increased on opposite side to lesion
Nystagmus suppressed by pursuit system
Nystagmus increases on foveal fixation

18
Q

What are the features of nystagmus caused by central vestibular disease?

A

Horizontal jerk
Fast phase opposite side to disease
Amplitude increased on opposite side to lesion
Nystagmus suppressed by pursuit system
Nystagmus increases on foveal fixation
May have vertical and torsional elements

19
Q

What are the features of nystagmus caused by cerebellar disease (horizontal)?

A

Jerky nystagmus
Fast phase in direction of lesion
Large amplitude, low frequency
Amplitude increases on affected side
No compensation from pursuit system

20
Q

What areas are diseased in nystagmus caused by cerebellar disease (vertical)?

A

Upbeat - due to disease of anterior vermis
Downbeat - due to malformation of Arnold-Chiari (increases on downgaze)

21
Q

What is gaze evoked nystagmus?

A

Unable to maintain eccentric gaze
Assoc with neurogenic and myogenic palsies
Fast phase towards affected side

22
Q

What is convergence retraction nystagmus?

A

Progressive loss of upgaze
Dissociation of light-near reflex
When upgaze attempted, rhythmic retraction and convergence

23
Q

What is the aetiology of convergence retraction nystagmus?

A

Pineal tumour
Midbrain tumour
Parinauds syndrome (compression of tectal plate caused by tumours)

24
Q

What is dissociated nystagmus?

A

Differing oscillations in each eye
Most common cause is internuclear ophthalmoplegia (INO): abducting nystagmus

25
What is INO caused by?
Lesion of MLF between 3rd and 4th nerve nuclei, associated with MS if bilateral Limited adduction on side of lesion, abducting nystagmus on opposite eye
26
What is see-saw nystagmus?
One eye elevates and intorts, other depresses and extorts
27
What is the aetiology of see-saw nystagmus?
Midbrain vascular disease Parasellar neoplasms Severe head injury
28
What tests should you do to investigate nystagmus?
VA (mono and binoc, N&D with AHP) CT Motility Convergence Binocular function Fundus and media Electrodiagnostics (VEP, ERG) Any other medical/imaging tests deemed necessary
29
What is the management of nystagmus?
Improve VA as much as poss Reduce AHP but maintain VA (prism to move eyes into null zone or convergence, or surgery) Ensure relevant services contacted, support at school/work in place Consider CLs - always looking through OC
30
When would you need to refer nystagmus? What urgency?
If acquired and not yet investigated. Urgent referral to neurology.
31
What are the characteristics of low vision nystagmus?
Pendular with slow rhythmic oscillation Often jerky on versions Can be unilateral Prognosis for good VA poor once nystagmus established
32
What are the characteristics of congenital idiopathic nystagmus?
Bilateral Horizontal Fast phase changes on right and left gaze - null point between the two Near VA better due to reduced nystagmus on convergence Worsens on attempted fixation
33
What are the characteristics of latent nystagmus?
Horizontal jerk nystagmus on occlusion of one eye (fast phase towards uncovered eye) No nystagmus when binocular May be manifest on versions Binoc VA better than monoc VA
34
What are the characteristics of manifest latent nystagmus?
Horizontal jerk nystagmus Associated with infantile esotropia Fast phase in direction of fixing eye Increased intensity on abduction May turn towards fixing eye
35
What are the characteristics of Spasmus Nutans?
Onset 3-18 months Jerky or fine, high frequency nystagmus Horizontal or vertical (or both) Varies with direction of gaze Head movements opposite to nystagmus direction and different frequency Often resolves by 3 years Can be result of CNS disease
36
What are some treatments to help nystagmus?
Mindfulness Acupuncture Pharmacological LVAs Botox