O+G Flashcards

(40 cards)

1
Q

Endometriosis risk factors

A

Nulliparty/late childbearing
Early menarche
Delayed menopause
Hydrocolpos
First degree relative with endo
White
Smoking
Low BMI

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Endometriosis symptoms and signs

A

Dysmenorrhoea
Dysparaeunia
Subfertility
Chronic or cyclical pelvic pain
Bloating
Lethargy
Dyschezia
Constipation
Low back pain
Dysuria (2/3 have interstitial cystitis)

Exam likely normal but also:
Tenderness or nodules/masses in adnexae/posterior fornix
Bluish haemorrhagic nodules in the posterior fornix
Decreased uterine mobility - may be fixed and/or retroverted
Uterine enlargement

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Endometriosis management

A

TXA for heavy bleeding
Suppression of ovulation for at least 6/12 via:
-POP (1st line)
-COCP (2nd line)
-IUD
-GnRH agonist (gosrelin)
Laparoscopic surgical Tx

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Endometriosis complications

A

Sub-fertility/infertility
Adhesions
Inflammatory bowel disease
Ectopic pregnancy risk is greater
?Ovarian cancer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ectopic pregnancy risk factors/at risk groups

A

Previous ectopic pregnancy
Previous tubal surgery or pathology
PID
Smoking
Current or previous IUD use
IVF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Indication for USS or endometrial biopsy in anovulatory bleeding. (Risk of cancer or hyperplasia)

A

<35yo and at least one of:
-chronic anovulation for 2-3 years
-diabetes
-FHx colon cancer
-infertility
-nulliparity
-obesity
-tamoxifen
Adolescent, obese, years of anov bleeding
>35, esp if obese
Not responding to medical therapy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Causes of chronic anovulation

A

Thyroid disorders
DM
PCOS (6-10)
Hyperprolactinaemia
Eating disorders
Some antipsychotics or antiepileptics (they cause raised prolactin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Menorrhagia causes

A

50% unknown
Coagulopathy (von Willebrands #1)
Thyroid dysfunction (hypo)
Fibroids
Endometrial polyps
Liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Menorrhagia treatment

A

POP
NSAIDs
TXA
Mirena
Endometrial ablation/polypectomy/ embolization/fibroidectomy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Menorrhagia investigation indications

A

HCG, CBC, TSH
Coag screen if:
-flooding
->7 days of bleeding
-FHx bleeding disorder
-hx tx for anaemia
-hx of excessive bleeding
USS to assess for structural abnormality
Endometrial biopsy if not responding to treatment or risk factors for cancer and >35yo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Excessive menstrual bleeding definition

A

Changing pads every 1-2 hours
Clots bigger than 1 inch
“very heavy” bleeding reported by patient

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Anovulatory bleeding - treatment

A

COCP
POP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Early pregnancy bleeding causes

A

Miscarriage - 10-20%
Ectopic pregnancy - 1-2%
Endometrial implantation
Gestational trophoblastic disease (rare)
Cervical and vaginal lesions (rare)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Anovulatory bleeding definition

A

Irregular or infrequent periods
Flow ranging from low to heavy
Includes:
-amenorrhoea (no periods for 3 cycles or more)
-oligomenorrhoea (occurs at periods of >35 days)
-metroragghia (irregular intervals and periods lasting >7 days)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Late pregnancy bleeding causes

A

Placental previa. Incidental finding in 2nd trimester, resolves in 90%
Placental abruption - 1% of pregnancies. #1 cause of serious PV bleeding in pregnancy. Fatal mortality 10-30%. 50% <36 weeks
Vasa previa - rare but up to 100% mortality as can cause foetal exsanguination

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Normal HCG rise

A

66% every 48 hours
(ectopic can mimic this in up to 20% of cases)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Late pregnancy bleeding management

A

Placenta previa - avoid PV digital exam as may exacerbate bleeding. Speculum is ok. Bedrest from 3rd trimester if sig bleed. Steroids. Avoid sex and tampons
Abruption - may require prompt delivery

13
Q

Risk factors for placenta previa

A

Multiparty
Tobacco smoking
Uterine curettage
Previous caesarian
Multiple gestations
Older age
Chronic HTN

14
Q

Risk factors for placental abruption

A

Pre-eclampsia
Chronic HTN
Multiparty
Maternal cocaine, tobacco or methamphetamine use
Previous abruption
Trauma/sudden deceleration injury
Uterine fibroids
Thrombophilias
Short umbilical cord

15
Q

Vasa previa risk factors

A

Low-lying and 2nd trimester placenta previa
IVF
Multiple gestation
Marginal cord insertion

16
Q

Abruption - presentation

A

Vaginal bleeding
Uterine/fundal pain
Back pain
Foetal distress
IUGR/pretem labour/feotal death may occur
DIC (10%)

17
Q

PPH definition and management

A

Minor = 500-1000ml <24 hrs post delivery
Major = >1000ml

IVL x2 large bore
Examine vagina looking for lacerations (more likely in absence of atony) or uterine inversion
Assess for uterine atony - if present give 10 units oxytocin IV and perform bimanual massage

If major PPH commence warmed IVF
-up to 3.5L then move to blood
-after 4 units blood give FFP
-keep fibrinogen >2g/L by use of cryoprecipitate
-TXA
-platelets if <75

18
Q

Hyperemesis gravidarum facts

A

1% of pregnancies
Starts week 4
Peaks week 9
90% resolved by 16-20 weeks
Unlikely if begins after 12 weeks
More likely in Pacific women (?H. pylori ?thyroid)

19
Q

Hyperemesis gravidarum treatment

A

Small meals, low in fat, high in carbs
Acupressure
Lie down for nausea
Frequent small volumes fluid PO
Avoid getting hungry
Check ketones
Metoclopramide
Cyclizine
Prochloperazine
Promethazine
Ondansetron last-line
If severe consider thiamine and omeprazole and referral
Consider underlying H. pylori infection and hyperthyroidism

20
Pre-eclampsia definition
3-8% of pregnancies in NZ New HTN after 20 weeks AND: -proteinuria (+/- oedema) -LFT dysfunction -renal impairment -haematological dysfunction eg low platelets, haemolysis -neurological dysfunction eg headaches, flashing lights, clonus -maternal organ dysfunction
21
Pre-eclampsia risk factors
Major: Existing HTN Diabetes Personal history of pre-eclampsia FHx pre-eclampsia SLE or antiphospholipid syndrome Oocyte donation Minor: BMI >35 Age >40 African, Indian, Maori or PI Primip Multiple pregnancy Change in partner Sperm donation FHx PET on fathers side
22
PET features (hx, exam)
Pregnancy >20 weeks AND any of: -new oedema -severe headache -visual sx eg scotoma -chest pain -SOB -vomiting -upper abdominal pain esp RUQ -reduced urine output -reduced foetal movements Exam -HTN - 140/90, severe if 160/110 -hyperreflexia -abdominal tenderness -oedema
23
PET treatment
Refer to hospital, do not do bloods Control BP with nifedipine, labetalol, hydralazine Magnesium sulphate
24
Emergency contraception: how to
Check date of LMP and calculate date of likely ovulation Check timing of UPSI Consider possibility of non-consensual sexual activity Consider pregnancy test Consider STI test Consider whether ECP or IUCD (copper only) ECP: 1.5mg levonorgestrel single dose Check no contraindications eg VTE hx, active breast cancer Higher risk of failure in: -UPSI close to ovulation -subsequent UPSI in same cycle -missed first week of COCP -weight >70kgv(consider double dose) -increased time since UPSI (12 hours ideal, 72-96 is limit IUCD can be used up to 120 hours post UPSI, is most effective. Use ECP while organising
25
Urethral discharge treatment
Azithromycin 1g stat or doxy 1/52 If purulent add ceftriaxone
26
Patient advice and FU post PID
Use condoms for 14 days post treatment and 7 days post partner treatment 3/12 partner tracing Repeat bimanual in 3/7 - if still sore refer to O&G Repeat STI check in 3/12
27
HSV facts
20% of carriers will have no lesions Transfer can occur without lesions but 100-1000x more likely with lesions Fomite transfer highly unlikely as virus does not survive at room temperature Lesions last 4-15 days Recurrences can be triggered by: -sunlight -stress -minor trauma -pre-menstrual Complications include: -urethritis -proctitis -neurogenic -leg and thigh pain -meningitis -widespread if immunocompromised
28
HSV treatment
Initial presentation: -7-10/7 valaciclovir Recurrence can be either episodic if not severe symptoms or suppressive if severe or frequent symptoms Refer if herpes proctitis or pregnant
29
HSV patient advice
Partner infection does not necessarily indicate infidelity Use salt washes Dilute urine by drinking more Pee in bath/shower Topical anaesthetic - may sting initially No cancer risk Avoid sex until lesions healed Printed information
30
HPV facts
Long latency 75% of population affected Pain, bleeding and itch common sx Self-treatment with podophyllotoxin or imiquimod. Clinic treatment with cryotherapy
31
HPV need for referral
Pregnant Extensive Cervical Immunosuppressed/HIV Diabetes Intra-urethral Treatment failure
32
Primary syphilis features
50% asymptomatic Incubation 10-90 days Chancre, not always painless, not always solitary 30% multiple lesions Inguinal LN
33
Secondary syphilis features
2-24 weeks latency 90% involve skin changes -usually trunk but can be palms and soles -can be confused with guttate psoriasis or pityriasis rosea -alopecia -condylomata lata -neurological signs Some constitutional sx
34
Tertiary syphilis
Gumma Aortitis Neuro sx: paraesthesia, ataxia, dementia, deafness, visual impairment
35
Chlamydia treatment
Doxycycline first line as better at treating rectal chlamydia (which is asymptomatic in 90% of women) Azithromycin second line for those unlikely to take full course. Also contributes to resistance