OB Flashcards
what are the criteria for preeclampsia?
-after 20th week
-140/90 on 2 occasions at least 8 hours apart
-one of more of the following: proteinuria, new onset headaches/visual disturbances, thrombocytopenia, impaired liver or kidney function, or pulmonary edema
what is the cure for preeclampsia?
delivery is the only cure
what is eclampsia?
severe preeclampsia in which seizures occur
what are the effects of preeclampsia and eclampsia on fetus?
-long-standing HTN leads to placental insufficiency which impairs the nutrient and 02 to fetus which results in IUGR.
-placental abruption is also more frequent
HELLP syndrome stands for?
- H = hemolysis
- EL = elevated liver enzymes
- LP = low platelet count
when does HELLP syndrome occur?
-4-12% of all those with preeclampsia, most often in 27-37 weeks but also may develop postpartum
how does the mother present with HELLP syndrome?
- often present with flu like symptoms including headache, nausea, vomiting, and visual disturbances
- pain in the upper right quadrant is related to liver dysfunction, but may be misdiagnosed as GI or gallbladder disease
what is the treatment of HELLP syndrome?
platelet transfusions are given immediately before birth - 20,000/mm3 before vaginal delivery or 50,000/mm3 before C-section.
HELLP syndrome treatment?
Immediate delivery of the fetus and platelet transfusion ideally prior to delivery
does insulin cross the placenta?
No
explain the effects of diabetes on a fetus/newborn
The fetus is exposed to elevated blood glucose levels which restrict fetal growth. at 20 weeks, the pancreas of the fetus be insipidus insulin the combination of elevated blood glucose from the mother, combined with elevated insulin from the newborn triggers rapid fetal growth increasing fat, and glucagon store at birth, sudden withdrawal of maternal glucose, combined with continued insulin production of the newborn results in hypoglycemia
around how many weeks does the fetus start producing insulin?
20 weeks
does glucose cross the placenta?
Yes
what is sickle cell?
Recessive genetic disorder of chromosome 11, causing hemoglobin to be defective, so that red blood cells are sickle shaped and inflexible, as result accumulation in small vessels creates blockages and causes pain
effects of sickle cell anemia on a pregnant woman
- Increase risk urinary and pulmonary infections, congestive heart failure, acute renal failure (all of which at any time can trigger crisis that puts the fetus at risk)
- Fetal mortality rates are about 18% due to sickling in the placenta
Effects of sickle cell anemia on the fetus
- fetal death rates are about 18% due to the sickling of the placenta
- neonates are at increased risk for prematurity and IGUR
cardiac disease in the mother puts baby at what risk? what is recommended?
5-10% of babies will have cardiac anomalies, fetal echocardiogram is recommended
what is the recommended iron dosing for anemia?
60-120mg daily, avoid caffeine and dairy, take with a source of vitamin C
foods high in folate
green leafy vegetables, liver, citrus fruits, legumes, nuts, and grains
recommended supplementation of folate/folic acid
folate 600-1000mcg daily, folic acid 1-5mg daily
naegele’s rule
first day of LMP minus 3 months plus 7 days = gestation age
vasa previa
one or more of the fetal blood vessel lie across the cervical OS
chorionic villus sampling
CVS; inserting a catheter into the ulterior to obtain placental villi for testing; preformed at 10-13 weeks gestation; chromosomal, DNA and enzymatic analysis is done to the tissue
amniocentesis
15-20 week; US guided, needled is inserted into amniotic pocket; 15-20ml if amniotic fluid needed