OB Cards Flashcards
(68 cards)
Antibodies that do NOT cause hemolytic disease
Lewis, I, Duffy (Fyb)
Antibodies that DO cause hemolytic disease
Kidd, Kell, Duffy (Fya)
Antibodies that cause severe hemolytic disease of newborn
D, E, C, k1 (Kell) ‘DECK’
Aneuploidy risk by maternal age of Down Syndrome
30: 1/1000
35: 1/365
40: 1/100
45: 1/36
Aneuploidy risk by maternal age of any chromosomal abnormality
30: 1/500
35: 1/180
40: 1/50
45: 1/18
When to perform NT
11.0-13.6, ideally 12th week
Abnormal NT size?
> 3mm
Concerns if +NT but negative genetics?
Suspect cardiac anomaly
Elevated NT associated with which aneuploidies?
18, 21
Molecules that cross placenta
PIMP TILTT
PTU, Iodine, Mag, Propranolol
TRH, IgG, LATS, T3, T4,
Molecules that do NOT cross placenta
Tyrosine, Triiodothyronine, Insulin, Heparin, Prednisone, TSH, Glucagon
Molecules that cross placenta via simple diffusion
O2, CO2, electrolyes, ketones
Molecules that cross placenta via active transport
PICA
Phosphorous, Iron, Calcium, Amino Acids
Molecules that cross placenta via facilitated diffusion
-ose
Glucose, sucrose, fructose
Molecules that cross placenta via endocytosis
IgG
Molecules that cross placenta via bulk flow
Water
Molecules that cross placenta via carrier mediated
Iodine
Expected O2, CO2, pH, base excess of umbilical vein
O2: 30
CO2: 40
Base excess: -2.4 to -4.5
pH: 7.32-7.34
Expected O2, CO2, pH, base excess of umbilical arteries
O2: 20
CO2: 50
Base excess: -2.7 to -5.6
pH: 7.24–7.27
Recommended mg iron/day
4mg/iron QD
Which reflects more of the fetal acid/base status, artery or vein gasses?
Artery (coming FROM fetus, shows how it metabolizes)
CV changes increased in pregnancy
HR, CO, plasma volume, red cell volume
CV changes decreased in pregnancy
SVR
Renal changes increased in pregnancy
GFR (50%)