OB exam 1 Flashcards
(116 cards)
Breasts
- Don’t finish developing until after first baby
- Growth caused by increase in progesterone at puberty
- Function: lactation, organs for sexual arousal
- Physiologic alterations in size and activity at minimum 5-7 days post menstruation (do BSE at this time)
Endometrial cycle phases
- Menstrual: shedding of top 2 layers of endometrium
- Proliferative: rapid growth lasting from day 5-14 (building up)
- Secretory: ovulation until 3 days before next period. After ovulation, increase in progesterone and endometrium is filled with blood and glandular secretions (lush and ready to fertilize) Implantation generally 7-10 days after ovulation.
- Ischemic: blood supply to endometrium is blocked and necrosis develops leading into menstruation
Hypothalamic-pituitary cycle
Regulates FSH and LH.
1. FSH: anterior pituitary
-Follicular phase: egg develops in ovary; causes the variation in period length
- LH: posterior pituitary
-Luteal phase: after ovulation, progesterone is released to prepare for fertilization
Ovarian cycle
- Estrogen: “fertilizer”
- Progesterone: “lawn mower”
- 14 days after ovulation, another cycle occurs
Prostaglandins
-Oxygenated fatty acids classified in hormones
-Effects on: ovulation (slough); fertility (move sperm along); changes in cervix and cervical mucus; tubal and uterine motility; sloughing of endometrium (menstruation); onset of abortion (spontaneous and induced); onset of labor (term and preterm)
-Semen has prostaglandins
Climacteric and menopause
- Climacteric: pre to post menopause
-ovarian fxn and hormone fxn decline
-onset of premenopausal ovarian decline to postmenopause - Menopause: no period after a year
-last period dated with certainty after 1 year
-ovaries shrink
-35-60 yrs old - Perimenopause: decreased estrogen= irregular bleeding
-pregnancies can still occur
Sexual response
- Physical maturity at age 17 both sexes
- Sexual stimulation results in circulation to blood vessels (venous congestion)
- Arousal (orgasm): myotonia (muscle contraction)
- Four phases: Excitement, plateau, orgasmic, resolution
Health promotion adolescents
- First to enter healthcare system as young women
- Teenage pregnancies: sexually active without contraception have 90% chance of conceiving
-declined in last 10 yrs r/t more education and contraceptive use - Pap smear at 21
Health promotion adults
- Young and middle:
-Contraception
-Pelvic and breast screenings - Late reproductive:
-Chronic diseases emerge
-Increased risks with pregnancy
Prenatal care
- Important to seek early!! Abnormalities of fetus already present after 56 days of fertilization
Risk factors of fetal abnormalities
- Substance use and abuse: prescription, illicit, alcohol use, cigarette smoking, caffeine (linked to miscarriage)
- Nutritional problems: deficiencies (more common in women), obesity (an American problem), eating disorders (anorexia, bulimia), lack of exercise (150 min/week)
- Other: stress, mental health disorders, sleep (6-8 hrs good), environmental and work hazards, female genital mutilation (tribal practice to remove clit), human trafficking (prevalent in kc, sold into sex slaves, more in women and children)
Intimate partner violence
- Physical or emotional abuse (pregnancy increases the risk)
- Sexual assault
- Isolation
- Controlling all aspects of the woman’s life: money, shelter, time, food, reproductive coercion (destroys birth control)
Can be scars, bruises, broken bones or all mental
Assessment of the woman
- Physical exam and hx: done in a private relaxed enviornment
- Pelvic exam
-external inspection
-bimanual palpation: outside and inside
-rectovaginal palpation: hand outside and 1 finger in rectum and 1 in vagina
-vulvar self-exam: done easily with mirror to look for any abnormalities
-papanicalaou test: no douche, sex or vaginal meds 24-48 hrs prior - Adolescents (13-19 yrs): asked the same questions, pay attention to hints about risky behaviors, eating disorders and depression
Health screening for women
- Fasting BG (45+)
- Total blood cholesterol
- Lipid profile
- Urinalysis
- STI (<25 and as needed if sexually active)
- Mammogram (40)
- Clinical breast exam (20+)
- TB skin test
- Pap test (21-65; q3y until 30)
- Pelvic exam (until 70)
- Colon cancer screening (45)
- Bone mineral density (DEXA scan; 65)
Amenorrhea
Absence of a period
1. Primary causes:
-never started
-red flag by end of HS
-Autonomic: formed incorrectly at birth (pelvic exam, US)
-Endocrine
-Chronic disease
-Eating disorders
-Medications
- Secondary causes:
-result of pregnancy (most common cause)
-sign of variety of disorders
Hypogonadatropic amenorrhea
- Problem in central hypothalamic-pituitary axis
- Results from hypothalamic suppression
-Either a lesion or genetic inability to produce FSH and LH
-Ex: extreme activity can cause (usually secondary amenorrhea) - Management: counseling and education regarding stress, exercise, and weight loss; calcium and vitamin D
Dysmenorrhea
Dys= pain
-Pain during or shortly before menstruation (only a couple days; increased contraction of uterus)
- Primary: biochemical (arises from the release of prostaglandins) or abnormally increased uterine activity;
-Alleviating discomfort (medications, heat, alternatives: sex on first day of period will shorten and decrease severity of cramps) - Secondary: acquired menstrual pain (ex causes: STI, endometriosis: solved by surgery)
-Diagnosis and treat: pelvic exam, US, dilation and curettage, endometrial biopsy, laparoscopy
-Treatment directed to remove underlying pathology
-Menopause or suppression is a cure
Premenstrual syndrome (PMS)
Cyclic symptoms occuring in luteal phase of cycle (right before next cycle)
- Physical, psychologic and behavioral sxs
-30-80% of women experience
Premenstrual dysphoric disorder (PMDD)
Cyclic symptoms in the last 7-10 days of cycle (week to week and a half before period; right after ovulation)
-recognized in the DSM-5
-Severe variant of PMS
-3-8% of women
-Mood disorder (self destructive and homocidal; repetitive visions)
-May need counseling, hypnosis, acupuncture, SSRI’s used during the time (doesn’t take 4 weeks to get results in this case)
Endometriosis
Presence of growth outside of uterus (lesions)
-Sxs: dysmenorrhea, deep pelvic dyspareunia (painful sex)
-Treatment: Lupron drug therapy to supress ovulation; laparoscopy to get rid of lesions if trying to conceive
-Resolves at menopause (avg age 51)
Oligomenorrhea/hypomenorrhea
- Oligo: Infrequent
- Hypo: scant
Menorrhagia
Excessive mensturation
Metrorrhagia
bleeding between periods
Causes of abnormal uterine bleeding
- Pregnancy related conditions (miscarriage, abortion, ectopic)
- Lower reproductive tract infections (cervicitis, endometritis)
- Benign anatomic abnormalities
- Neoplasms
- Malignant lesions
- Trauma
- Systemic conditions (cushings, severe organ disease, thyroid disease)
- Iatrogenic (anticoagulants, medications, hormone use, tamoxifen)