Ob/Gyn Flashcards
(414 cards)
Sonographic findings with Trisomy 18 include all of the following except (A) IUGR (B) clenched hands (C) holoprosencephaly (D) cystic hygroma
(D) Cystic hygroma is associated with Turner syndrome, not trisomy 18.
Paternally derived triploidy has the following sonographic markers
(A) complete mole
(B) severe asymmetrical IUGR
(C) large placenta with multiple cystic areas
(D) oligohydramnios
(E) A and D
(F) B and D
(C) Paternally derived triploidy is associated with a relatively well-grown fetus that has a proportionate head size. The placenta is large with multiple cystic spaces resembling a molar pregnancy. This accounts for 90% of triploidy.
Maternally derived triploidy has the following sonographic markers
(A) complete mole
(B) severe assymetrical IUGR
(C) large placenta with multiple cystic areas
(D) oligohydramnios
(E) AandD
(F) BandD
(F) Maternally derived triploidy is associated with a small placenta. The fetus has severe asymmetric growth restriction and oligohydramnios.
Amniotic fluid is withdrawn from the gestational sac. Performed after 14 weeks with a low loss rate. It has a 0.3% risk of miscarriage.
Amniocentesis
Performed 10–12 weeks. Cannot rule out spina bifida. Can test for karyotype only. AFP is a fetal protein that may be tested for by concentration levels in the amniotic fluid or in maternal serum.
Chorionic villi sampling (CVS)
Performed 11–14 weeks. Increased loss rate and associated with talipes equinovarus. Early loss rate is thought to be associated with the unfused chorion and amnion. They are difficult to penetrate and often require multiple sticks.
Early amniocentesis
“Tags” chromosomes 13,18,21, X and Y for quick preliminary results It is considered experimental and requires amniocentesis follow-up. Fluorescent chromosomal markers are introduced into the amniotic fluid that “tag” or attach to certain chromosomes. These markers and chromosomes fluorescence allow for early preliminary detection of chromosomal abnormalities.
Fluorescence in Situ Hybridization (FISH).
Technically difficult procedure that tests fetal blood. It involves an insertion of a needle into the fetal umbilical cord and the withdrawal of fetal blood. It may be used in cases of anhydramnios, testing for isoimmunization, fetal blood typing, hemophilias, and other disorders.
Percutaneous umbilical blood sampling (PUBS)
The most common twin zygocity is (A) conjoined twins (B) monochorionic/diamniotic (C) dichorionic/diamniotic (D) monochorionic/monoamniotic
(C) Seventy-five percent of twins are dizygotic.
The “twin peak” sign is
(A) also known as the beta sign
(B) a triangular projection of chorion into the dividing membrane
(C) a sonographic predictor for dizygotic twins
(D) B and C
(E) all of the above
(D) The twin peak is formed when the placental tissue migrates between the chorionic layers. This is 94–100% predictive of dizygotic twins.
Which of the following statements about conjoined twins is not true?
(A) 60% are born alive
(B) 56% of conjoined twins are fused on the ventral wall
(C) polyhydramnios is commonly present
(D) the largest risk of fetal demise is because of cord entanglement
(D) Forty percent of conjoined twins are born stillborn. Fifty-six percent of conjoined twins are thoracoomphalopagus, thoracopagus, and omphalopagus. Polyhydramnios is present 50% of the time. Commonly, there is one umbilical cord that may have an abnormal number of vessels and is shared by the conjoined fetuses.
Shortening of the proximal limb. Shortening of the humerus and femur.
rhizomelia
Shortening of the middle portion of the limb (forearms and lower leg bones). Shortening of the radius/ulna and tibia/fibula.
mesomelia
Shortening of all portions of a limb. Shortening of the entire limb, but can also refer to shortening of a limb without specific reference.
micromelia
Shortening of the hand and foot bones.
acromelia
The most common short limb syndrome is (A) achondrogenesis (B) thanatophoric dysplasia (C) osteogenesis imperfecta (D) jeune thoracic dystrophy
B) The occurrence rate for thanatophoric dysplasia is 1/6000–1/17,000 births. Sonographic findings are polyhydramnios, severe rhizomelia, and micromelia with bowing. The thorax is bell-shaped, and the cranium is cloverleaf-shaped with hydrocephaly and frontal bossing.
What sonographic findings would be identified in a fetus with heterozygous achondroplasia? (A) hydrocephaly (B) frontal bossing (C) “bell shaped” thorax (D) “trident hand” (E) A and C (F) B and D (G) all of the above
(F) Heterozygous achondroplasia accounts for 80% of achondroplasias. It is the most common form of genetic skeletal dysplasia. It is often not identified before 26–27 weeks
What is the most common congenital facial anomaly? (A) proboscis (B) hypotelorism (C) isolated cleft lip/palate (D) low set ears
(C) It has a variable prevalence, with Native American being the highest at 3.6/1000 births.
3-D surface rendering is used to (A) obtain volume measurements (B) obtain technically difficult images (C) image fetal spine (D) image fetal face
(D) Three-dimensional imaging of the internal organs is termed volume imaging. Three-dimensional images of surface structures, such as the fetal face, is surface rendering.
The earliest age at which a gestational sac may be visualized by transvaginal sonography is (A) 4 weeks (B) 6 weeks (C)8 weeks (D)10 weeks
(A) A gestational sac can be visualized by transvaginal scanning as early as 4 weeks.
The optimal time for imaging cardiac structures is (A) 14–18 weeks (B) 18–24 weeks (C) 24–28 weeks (D) 28–32 weeks
(B) Cardiac imaging can be done earlier than 18 weeks, but is dependent on maternal habitus. After 24 weeks, the fetal bones become denser and more cal- cified and begin to limit the sonographic windows that allow visualization of the cardiac structures.
3D volumetric reconstructions are used to show all of the following except (A) fetal face (B) fetal limbs (C) organs (D) digits
(A) Three-dimensional imaging of surface structures, such as the fetal face, is termed surface rendering.
By 12 weeks gestational age, the sonographer can identify what abnormalities? (A) conjoined twins (B) anencephaly (C) duodenal atresia (D) A and B (E) all of the above
(C) Although duodenal atresia has been detected in the first trimester, the classic “double bubble” sign is not usually present until the late second and early third trimesters.
An unexplained increased MSAFP3 can cause what third trimester complications? (A) premature rupture of membranes (B) placental abruption (C) preterm labor (D) A and B (E) all of the above
(E) When the increased AFP is unexplained, it is thought to be because of an increased placental transfer of AFP. The placental dysfunction can occur with various placental abnormalities that may cause third trimester complications.