Obesity Flashcards

(42 cards)

1
Q

Obesity occurs..

A

when excess calories are stored as fat

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2
Q

Obesity

A
  • most prevalent preventable health problem in US
  • increase risk of morbidity and mortality
  • Nearly 70% of Americans are overweight or obese
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3
Q

Pathophysiology of Obesity

A
  • all body function requires energy
  • excess energy (kcals)/nutrients are stored as triglycerides in fat cells
  • Nutrients provide energy
  • 70% of energy expended goes to maintain BMR
  • Physical activity accounts for 5-10% of energy expended
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4
Q

Etiology of Obesity

A
  • excess energy and/or decreased energy expenditure
  • appetite
  • GI filling
  • Hormonal factors
  • emotions
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5
Q

Hormonal factors and Obesity

A
  • Leptin
  • Insulin
  • Thyroid Hormone
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6
Q

Risk Factors

A
  • heredity (25-40% of obesity)
  • physical inactivity
  • cultural factors
  • environmental factors
  • socioeconomic factors
  • psychological factors
  • addiction
  • coping mechanism
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7
Q

Adipose Tissue

A
  • mature adipose cells do not multiply
  • however, immature adipose cells multiply in presence of estrogen during puberty and late adolescents, during breastfeeding, overweight middle aged adults
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8
Q

Clinical Manifestations: Upper body obesity

A
  • waist hip ratio >1 in men, >0.8 in women
  • increased levels of circulating free fatty acids
  • increased risk of HTN, dyslipidemia, heart disease, stroke, hyperinsulinemia

APPLE

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9
Q

Complications of Obesity

A

-HTN
-Coronary heart disease
-Heart failure
-Stroke
-Metabolic syndrome
-Insulin Resistance
-DM2
-Sleep apnea
-Reproductive impairment
-Gallstones
-Cancer
Joint Pain/OA

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10
Q

Reproductive Impairment

A

Men: decreased androgen

Women: menstrual irregularity, polycystic ovary syndrome

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11
Q

Cancer

A
  1. colon
  2. breast
  3. endometrial
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12
Q

Obesity Management

A
  • Diet
  • Exercise
  • Behavior modification
  • Pharmacotherapy
  • Surgery
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13
Q

Apple vs. Pear

A

Pear is healthier, lower body weight

Apple: upper body weight

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14
Q

Diagnostic Tests: Anthropometry

A
  • BMI (kg divided by meters)
  • Skin folds
  • Hydrodensitrometry (water displacement)
  • Bioelectrical impulse (low energy electrical impulse)
  • Waist circumference (> or = 40 in men, 35 in women)
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15
Q

Diagnostic Tests: Labs

A
  • Thyroid panel
  • Serum glucose
  • Lipid profile
  • Electrocardiography
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16
Q

Pharmacologic Interventions

A
  • Amphetamine and non-amphetamine appetite suppressants
  • Appetite suppressant
  • Fat absorption inhibitor
  • OTC
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17
Q

Amphetamine and non-amphetamine appetite suppressants

A
  • Phentermine

- Stimulate CNS

18
Q

Appetite suppressant

A
  • Meridia (Sibutramine)
  • Appetite suppressant: lowers cholesterol and triglycerides, increase metabolic rate
  • removed from the market in 2010 due to increased risk of heart attacks and strokes
19
Q

Fat absorption inhibitor

A

Orlistat (Xenical)

20
Q

Qysmia

A
  • phentermine (stimulant) and topiramate (anti-seizure)

- avoid in pregnancy

21
Q

Belviq

A
  • locaserin HCl

- seratonin 2C receptor agonist/stimulator

22
Q

Methycellulose

A

bulk-forming product

-creates sensation of fullness

23
Q

Nutrition

A
  • regular, small servings
  • create 500-1,000 calories deficit
  • “yo-yo” dieting may result in metabolic deficiencies that make subsequent weight loss more difficult
24
Q

women calorie recommendation

A

1,000-1,200 kcal

25
less than 1,200 cals
may result in lean tissue loss and nutritional deficits
26
Aerobic Exercise
30-40 minutes five or more days per week increases BMR increases energy consumption preserve lean muscle mass
27
Behavioral modifications
- food diary - replace eating with other habits - identify triggers
28
Surgery
morbidity obese and unable to lose weight through dieting or exercising or have serious obesity-related complications
29
Contrave
naltrexone, an opioid antagonist, and bupropion, an antidepressent
30
Post-Operative Interventions
- monitor vitals - monitor I&O - Assess bowel sounds - monitor NG tube as ordered - NPO for 3 days or until peristalsis returns
31
Complications of Post-op Bariatric Surgery
1. infection and/or hemorrhage 2. dumping syndrome 3. Diarrhea 4. hypoglycemia 5. dehydration 6. gastric leak leading to infection/sepsis or ulceration
32
Deficiencies caused by Bariatric Surgery
1. Vitamin B12 (most significant) 2. Calcium 3. Iron 4. fat-soluble vitamins (A,D,E,K???)
33
Saxenda
liraglutide - glucagon-like peptide-1 receptor agonist - daily SQ injection - not recommended as first line therapy
34
Vitamin B12
-decreased absorption of Vit B12 from intestinal tract signs and symptoms: - pallor, - fatigue, - weight loss, - smooth, - beefy tongue, - slight jaundice, - paresthesia of hands and feet - disturbances of gait and balance
35
3 types of surgeries
1. Restrictive 2. Malabsorptive - not doing anymore 3. Restrictive/Malabsorptive
36
Restrictive/Malabsorptive Surgeries
- Gastric bypass | - duodenal switch
37
Restrictive Surgeries
- Gastric banding - Gastric sleeve - Gastric stapling
38
Treatment for Vitamin B12 deficiency
1. Increasing dietary B12, may not be effective | 2. IV replacement (severe), not oral due to malabsorption and gastric issues
39
Dumping Syndrome
rapid emptying of gastric contents into small intestines following gastric resection -water drawn into intestines through osmosis - typically happens 30 min post prandial - N/V - Abdominal fullness/cramping - Diarrhea - Palpitations - Tachycardia - Perspiration - Weakness - Dizziness - Borborgyums - noises of gas and fluids through bowels
40
Patient Education for Dumping Syndrome
- avoid sugar, salt, and milk - eat a high protein, high good fat, and low carb diet - eat small meals - avoid consuming fluids with meals - avoid very hot or very cold foods/drinks - lie down after meals - take antispasmodic medications as prescribed
41
Patient Education: Bariatric Syndrome
- avoid alcohol and carbonated beverages - Avoid foods high protein, saturated fat (fried foods), and sugar foods/drinks (fruit juice) and avoid simple carbs - eat slowly and chew well - take nutritional supplements - progress diet as ordered - monitor for s/s complications
42
men calorie recommendation
1,200-1,600 kcal