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Flashcards in OBJ - Protein Synthesis Deck (3)
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1
Q

Sketch the cloverleaf structure of a tRNA, and list the structural and functional features that are common to tRNAs.

A

3’ CCA tail = acceptor stem that AA binds to (7 base pairs)
D Arm/Loop = 4 base pairs
Anticodon Arm = 5 base pairs with Anticodon
T Arm/loop = 5 base pairs TΨC
Variable loop
5’ Terminal phosphate group

AA determined by Anticodon & variable loop

2
Q

Describe how amino acids are polymerized by the ribosome, including the factors and interactions that ensure the fidelity of the reaction.

A

5’ -> 3’ Amino Terminus to Carboxyl Terminus
1st AUG = beings coding Methionine
UAA = STOP codon

3
Q

Spliceosome

A
  • Assembled by 5 snRNPS
  • U1-U6
  • Removes introns from transcribed pre-mRNA