Obstruction/reflux Flashcards

(30 cards)

1
Q

international reflux study committee grading of reflux

A

grade 1 reflux into ureter only
grade 2 reflux into renal pelvis
grade 3 mild dilatation of ureter and pc system
grade 4 - moderate dilatation, tortuous ureter, blunting fornices but papillary impression remain
grade 5 - severe dilataion, tortuous, loss of fornices and papillary impressions

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2
Q

incidence of PUV

A

1 in 4000

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3
Q

initial management of PUV

A

US on day 2 with creatinine – when creatinine not reflective of maternal
Then divide into two groups
Normal creatinine, passing urine, HUN mild – can give trimethoprim 2mg/kg orally at night, MCUG as OP, review result referral to local paed urology department
If plasma create raised, markedly abnormal US, not passing urine, trimethoprim 2mg/kg at night, catheterise urethral or SPC, monitor post ob diuresis can be up to 8-10/kg/hr
If abnormal creatinine measured bicarb as become acidotic and may require oral bicarb
Abnormal renal function involve paed nephrologist

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4
Q

initial management of PUV

A

US on day 2 with creatinine – when creatinine not reflective of maternal
Then divide into two groups
Normal creatinine, passing urine, HUN mild – can give trimethoprim 2mg/kg orally at night, MCUG as OP, review result referral to local paed urology department
If plasma create raised, markedly abnormal US, not passing urine, trimethoprim 2mg/kg at night, catheterise urethral or SPC, monitor post ob diuresis can be up to 8-10/kg/hr
If abnormal creatinine measured bicarb as become acidotic and may require oral bicarb
Abnormal renal function involve paed nephrologist
then MCUG
then cystoscopy and fulguration of valves
Repeat cystoscopy at 6 weeks to 3 months postop

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5
Q

4 types megaureter

A

reflux - VUR management
obstructing - conservative, stent +/- dilatation, refluxing implant, ureterostomy, reimplant
obstructing and refluxing - reimplant
non reflux non obstructive

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6
Q

definition mega ureter

A

> 7mm on 3rd trimester US

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7
Q

invesitgations megaureter

A

US check bladder
MCUG any reflux?
MAG3 - obstruction and differential function
cystoscopy and retrograde in selected cases

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8
Q

causes secondary megaureter

A

PUV, urinary stones, bladder dysfunction, ureterocele, ectopic ureter, diabetes insipidus

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9
Q

indications surgery in megaureter

how many require intervention

A
10-30%, usually in first 2 years life
majority need no intervention esp if below 10mm
give abx to all when born
impaired function DRF <40%
serial drop renal function
evidence increasing HN on US scans
infection episodes
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10
Q

surgery options megaureter

A

stent temporary with vuj dilatation +/- cutting can cure in 50% cases
then refluxing reimplant temporary, can do ureterostomy
then non refluxing reimplant - ureteroneocystotomy which will need end tapering
don;t forget circumcision if infections!

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11
Q

causes antenatal hydronephrosis based main post natal diagnosis

A
watson paper
50% non specific  dilatation
11% PUJO
12% VUR
6% MCDK
4% duplex ureterocele
2% VUJO
1% PUV
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12
Q

definition AN hydro

A

7 or more mm in third trimester UK NHS foetal anomaly screening
measured AP at renal hilum

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13
Q

SFU grading AN hydro

A

1= prominent pelvis
2 = dilated pelvis, some calyces visible
3 - dilated pelvis and calyces all seen
4= greater pelvic and calyceal dilatation, cortical thinning

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14
Q

who needs post natal ix of AN HN (4)

A

unilateral RPD >10mm at 32 weeks
bilateral RPD with APD >6mm at any gestational age
RPD in solitary kidney
RPD with ureteric dilatation

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15
Q

which AN will resolve

A

APD <12mm 98% will resolve stabilised or improved on FU

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16
Q

managment post natal HN

A

first scan between 48 hours and 4 weeks

OPD US in 2-6 weeks no prophylaxis, confirm measurement, decide if any further investigation

if 2cm need MAG 3 for drainage and function

bilateral dilatation need earlier US and MCUG (PUV) also check baby’s back
MAG3 with diurectic can be in a few months

17
Q

which AN HN are higher risk (5)

A
bladder abnormal
HN in solitary
bilateral severe HN
abnormal parenchyma
palpable kidney or bladder, poor stream
18
Q

indications for pyeloplasty(3)

A
split differential less than 40
serial function decline 10-15%
massive HN
flank mass
symptoms pain haematuriai UTI
19
Q

US features MCDK (3)

A

check CL kidney
higher incidence VUR (20%), PUJO, VUJO, dysplasia
cysts with wall in between, non communicating
atresia ureter/pelvis
no renal parenchyma

20
Q

natural history of MCDK

A

half will involute
same size 2-37%
enlarge 1-18%

21
Q

follow up of MCDK

A

us at 2 year, 5 years and 10 years
monitor hypertension, proteinuria
see if involutes with compensatory hypertrophy
DMSA confirm no function at 6-12 months

22
Q

how many AN HN is physiological or transient?

23
Q

what is sig AN HN?

A

1-2 cm in third trimester

24
Q

monitoring of PUJO

A

until age 10, scan every 2 years

25
PUJO and big palpable kidney
can do nephrostomy check function MAG3 if borderline can do DMSA can do nephrostogram confirm dx can see if nephrostomy improves function if 10% or more can do pyelplasty fuction may improve if MAG3 and DMSA confirm less than 10% function and normal CL kidney then nephrectomy
26
sepsis with VUJO management
``` 24-48 hours antibiotics if doesn't settle stent -difficult in small child nephrostomy or cutaneous ureterostomy alternative is a refluxing ureterostomy - side to end anastomosis just above VUJ ```
27
sting vs HIT
STING inject 6 oclock into bladder mucosa to lift up ureteric orifice as make mound HIT - hydrodistension with scope into distal ureter and inject into wall of distal ureter
28
whittaker test
``` nephrostomy and catheter in bladder saline with contrast at 10ml/min pressure in kidneyu and bladder if <15cm water then system not obstructed if more than 22 then obstructed 15-22 are equivocal ```
29
Dhillon GOSH natural history study
17% need surgery 56% stable 27% resolved gross HN AP diameter more than 5cm treatd 20-50mm not clear cut >30m, 55% will be treated
30
post operative pyeloplasty procedure
twoc next day clamp 48 hours nephro stent removed 7 days