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Neuro 03 > Ocular pharm > Flashcards

Ocular pharm Flashcards

1
Q

What characteristics of drugs allow for greater cornea penetration?

A

esters possess greaer lipid solubility → penetrate cornea → converted to active drug

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2
Q

Initial medical tx for Open angle glaucoma

A

Prostaglandin analog (PA)

  • Latanoprost
  • ↑ aqueous humor outflow
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3
Q

Side effect of Latanoprost

A

(it ↑ aqueous humor outflow)

Brown discoloration of iris

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4
Q

Brimonidine

A

↑ AH outflow and inhibits formation of AH

alpha 2 adrenergic agonist
add on 2nd line (to latanoprost, the PG analog)

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5
Q

Cholinergic agonists: what effects on glaucoma?

List 2

A

aka Miotics
↑ AH outflow

Pilocarpine
Echothiophate

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6
Q

Beta Adrenergic antagonist to tx glaucoma

A

Timolol

↓ AH production

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7
Q

Carbonic anhydrase Inhibitor to tx glaucoma

A

Dorzolamide

↓ production

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8
Q

2 drugs used to tx essential tremors

A

Primidone

Propanolol

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9
Q

2 drugs used to tx HD

A

Tetrabenazine

Haloperidol

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Neuro 03 (16 decks)

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