Odontogenic Neoplasms Flashcards
(80 cards)
What are the three tumors of odontogenic epithelium?
- ameloblastoma - peripheral ameloblastoma
- adenomatoid odontogenic tumor
- calcifying epithelial odontogenic tumor (CEOT, Pindborg tumor)
What are three mixed odontogenic tumors?
- ameloblastic fibroma
- ameloblastic fibro-odontoma
- Odontoma
What are two tumors of odontogenic ectomesenchyme?
- odontogenic myxoma
2. cementoblastoma
Ameloblastoma is a ___ but locally aggressive neoplasm of odontogenic epithelial origin that histologically resembles the ameloblasts of the ___ ___, but no ___ is produced by lesional cells.
benign; enamel organ; enamel
T/F. The frequency of ameloblastoma equals the combined frequency of all other odontogenic tumors.
True.
Even tho ameloblastoma is among the more common of the odontogenic neoplasms, it still constitutes only about ___ % of oral pathology accessions.
0.2%
T/F. Ameloblastoma is commonly seen in women around the age of 20.
False, ameloblastoma has NO SEX predilection and is diagnosed around 33 years of age.
Most ameloblastomas occur in the ___ usually in the ___-___ region and about ___% are associated with an ___ tooth.
mandible; molar-ramus; 20%; impacted
T/F. Ameloblastomas are fast-growing lesions that destroy tissue by perforating bone.
False, Ameloblastomas are SLOW growing lesions that destroy tissue by expanding (very dramatically) rather than perforating bone.
T/F. Typically ameloblastomas are asymptomatic except for swelling.
True.
T/F. Ameloblastomas are small lesions that present as unilocular radiolucencies with well-defined, sclerotic borders.
False, Ameloblastomas are small lesions that present as unilocular radiolucencies with well-defined, but NOT sclerotic borders.
As ameloblastomas progress, the classic multilocular, expansile radiolucency develops, known as “___ ___” or “___”. They may displace teeth and/or resorb roots
soap bubble; honeycomb
What are the most often seen forms of ameloblastoma?
follicular and plexiform
Ameloblastomas have small tumor ___ and show a single layer of tall ___ or ___ cells at their periphery with ___ ___. What does this mean?
islands; reverse polarization
the nuclei are polarized away from the basement membrane
What is found in the center of an ameloblastoma’s tumor islands?
loosely arranged polyhedral epithelial cells that resemble stellate reticulum
How is ameloblastoma treated?
depends on size
small: aggressive curettage or small en bloc resection
large: en bloc resection or segmental resection with reconstruction
___ ameloblastomas are treated more aggressively due to their anatomic location near the sinus.
Maxillary
Prognosis of ameloblastoma is guarded because with simple curettage, recurrence is reported to be ___-___%. Even with marginal resection, recurrence rates up to ___% have been reported.
55-90%; 15%
T/F. Ameloblastomas can be fatal, especially with lesions in the maxilla. Malignant transformation is rare and ameloblastoma requires follow-up for 8-10 years.
Both statements are true.
What is a soft tissue variant of ameloblastoma that has no or limited bone involvement, no radiographic findings, is asymptomatic and presents as a gingival mass in middle-aged adults, usually in the mandible?
peripheral ameloblastoma
Peripheral ameloblastoma looks like many gingival ___, is less than ___cm in diameter and can be cured with ___. It has little tendency to recur.
bumps; 2; biopsy
What disease is a asymptomatic swelling discovered incidentally whose histogenesis is enamel organ or dental lamina rests?
Adenomatoid Odontogenic Tumor
T/F. AOT is seen in the mandible of male patients over 20
False, AOT is seen in the MAXILLA of FEMALE patients UNDER 20
What percentage of AOTs are found in the anterior jaws? What percentage of AOTs are associated with an impacted tooth?
75%
75%
