Odontogenic Neoplasms Flashcards

(52 cards)

1
Q

3 tumors of Odontogenic Epithelium

A

1) Amolblastoma
2) Adenomatoid Odontogenic Tumor
3) Calcifying Epithelial Odontogenic tumor (CEOT)

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2
Q

3 mixed odontogenic tumors

A

1) Ameloblastic Fibroma
2) Ameloblastic Fibro-odontoma
3) Odontoma

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3
Q

2 tumors of odontogenic Ectomesenchyme

A

1) Odontogenic Myxoma

2) Cementoblastoma

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4
Q

Benign, but locally aggressive neoplasm of odontogenic epithelial origin that resembles the ameloblasts of the enamel organ, except no enamel is being produced

A

Ameloblastoma

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5
Q

What is the most common odontogenic tumor

A

Ameloblastoma, more common than all other combined

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6
Q

Percent of oral pathology accession Ameloblastoma accounts for, sex predilection, average age

A
  • 0.2% of oral pathologies
  • No sex
  • 33 years old
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7
Q

Area Ameloblastoma are most common and percent associated w/ impacted teeth

A
  • Molar-ramus area of the mandible

- 20% associated w/ impacted teeth

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8
Q

Signs and symptoms of an Ameloblastoma

A
  • Slow growth, destroying tissue and expanding (not perforating) bone, usually asymptomatic except for swelling
  • May displace or resorb roots
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9
Q

Radiographic appearance of Ameloblastoma (small and large)

A
  • Small- Unilocular radiolucency w/ well defined borders

- Large- Multilocular soap bubble appearance

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10
Q

Typically plexiform and follicular pattern w/ single layer of columnar ameloblast like cells at periphery w/ nuclei polarized away from BM and tumor islands composed of polyhedral epithelial cells that resemble stellate reticulum

A

Ameloblastoma

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11
Q

Treatment and prognosis for Ameloblastoma, which arch should they be treated more aggressively

A
  • Small- Aggressive curretage or small en bloc resection
  • Large- En bloc or segemental resection and reconstruction
  • Maxillary
  • Guarded (55-90% recur w/ curretage, 15% recur w/ marginal resection)
  • Can be fatal, rare malignant transformation, follow up for 8-10 years
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12
Q

Asymptomatic gingival mass w/ no or minimal bone involvement

A

Peripheral Ameloblastoma

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13
Q

Age Peripheral Ameloblastoma is seen

A

Middle aged adult

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14
Q

Clinical presentation and treatment of Peripheral Ameloblastoma

A

Many gingival bumps (<2 cm), biopsy is currative

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15
Q

Asymptomatic swelling of enamel organ or dental lamina rests often discovered incidentally

A

Adenomatoid Odontogenic Tumor

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16
Q

Age, sex, and location (%s) Adenomatoid Odontogenic Tumor are sen

A
  • Most under 20
  • 2:1 F, 2:1 max
  • 75% in ant jaw
  • 75% w/ impacted tooth
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17
Q

Radiographic appearace of Adenomatoid Odontogenic Tumor

A

Well circumscribed unilocular radiolucency, pericoronal radiolucency may extend apically beyond DEJ
- Seperation of roots and displacement of teeth

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18
Q

Tumor cells forming swirling spindle cell nests and duct like structures (adenomatoid), foci of basophilic material

A

Adenomatoid Odontogenic Tumor

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19
Q

Treatment and Prognosis of Adenomatoid Odontogenic Tumor

A
  • Enucleation and excellent
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20
Q

Rare odontogenic epithelial neoplasm that is thought to be from stratum intdermedium

A

CEOT (Pindborg Tumor)

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21
Q

Age and location common w/ CEOT

A
  • 40

- 2:1 mandible (esepecially posterior)

22
Q

What are the symptoms and what is a CEOT usually associated with

A
  • Swelling

- Usually impacted tooth

23
Q

Radiographic findings of CEOT

A
  • Small- well circumsribed radiolucenct

- Can become multilocular w/ radiopaque flecks

24
Q

Tumor w/ proliferation of polyhedral epithelial cells w/ eosinphilic cytoplasm w/ pleomorphic nuclei

25
Structures in CEOT where epithelial cells stain eosinophilic and homogenous material stains amyloid where calcifications develop and form lamellated structures
Liesegang rings
26
Treatment and prognosis of CEOT
- Conservative excision | - Recurs 15%
27
Mixed odontogenic tumor w/ proliferationg odontogenic epithelium in a cellular ectomesenchyme resemling the dental papilla
Ameloblastic Fibroma
28
Age and location common w/ Ameloblastic Fibroma
Younger patients, 70% in posterior mandible
29
Symptoms/radiographs of small/large Ameloblastic Fibroma
- Small- Asymptomatic and uni - Large- Painless swelling, multi - Margins are sclerotic or well defined
30
Tumor w/ myxoid CT resembling dental papilla w/ strands of odontogenic epithelium resembling the dental lamina (can vaguely resemble ameloblastoma)
Ameloblastic Fibroma
31
Treatment and prognosis for Ameloblastic Fibroma
- Aggressive curettage | - Good, 15% recur, low transformation
32
Odontogenic tumor w/ features of ameloblastic fibroma admixed w/ and odontoma
Ameloblastic Fibro-Odontoma
33
Age and symptoms w/ Ameloblastic Fibro-Odontoma
- 10 years | - Asymptomatic unless failure of tooth eruption or swelling
34
Location of Ameloblastic Fibro-Odontoma
- Equal max and mand | - Radiolucency w/ calcified material overlying and impacted tooth
35
What type of odontoma is the odontoma portion of a Ameloblastic Fibro-Odontoma
Complex
36
Treatment and prognosis for Ameloblastic Fibro-Odontoma
- Curretage | - Excellent
37
Probably not a true neoplasm but an odontogenic hamartoma
Odontoma
38
What are the 2 forms of Odontomas and where are they located
1) Compound (anterior jaw) | 2) Complex (posterior jaw)
39
Age, associated, and location of Odontomas
- 14 years old - Usually w/ unerupted tooth - Max a little more than mand
40
How does a compound Odontoma present
- Collection of small malformed teeth surrounded by radiolucent rim overlying an impacted tooth
41
How does a complex Odontoma present
- Calcified mass that can have density of tooth, surrounded by radiolucent rim overlying and impacted tooth (shows mix of dentin, emamel, cementum, odontogenic epithelium and dental papilla)
42
Treatment and prognosis for Odontoma
- Enucleation, excellent
43
Benign neoplasm of odontogenic origin because it only affects the jaw as a central lesion
Odontogenic Myxoma
44
Age, location, and symptoms of Odontogenic Myxoma
- Younger adults (25-30) - Mandible slightly more than max - Larger lesions expansion of bone
45
Radiographic Odontogenic Myxoma
- Uni then multilocular, soap bubbl - Can displace teeth/roots - Thin, wispy trabecuclae of residual bone often at right angles
46
Tumor that has spindle or stellate shaped fibroblastic cells in a myxoid background, infiltrates adjacent bony trabeculae
Odontogenic Myxoma
47
Treatment and prognosis of Odontogenic Myxoma
- Small- curretage - Large- en bloc or segemental resecetion - Good, 25% recur
48
Well-cirumscribed radiopaque mass w/ a radiolucent border that fuses to the resorbed root of a mandibular first molar
Cementoblastoma
49
Age, location, and signs/symptoms of Cementoblastoma
- Patients under 25 - Mand molar - Slow growing, and pain and swelling seen 67% of tme
50
Has trabeculae of mineralized material that resembles cementum and are rimmed by plump angular cells that represent neoplastic cementoblasts
Cementoblastoma
51
Differential diagnosis for Cementoblastoma and distinguishing feautre
Osteoblastoma/sarcoma | - Fusion to root is distinguishing feature
52
Treatment and prognosis for Cementoblastoma
- Extraction of tooth and enucleation - RCT, enucleation and amputation of involed root - Excellent prognosis