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Old Questions Flashcards

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1
Q

In pts with anemia of vitamin B12 deficiency we are afraid of ?

A

Stomach cancer

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2
Q

Brachytherapy is ?

A

Radiation where radiation source is placed inside

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3
Q

Which isn’t a complication of testicular cancer?

A

Abnormalities on future children

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4
Q

Palliative chemotherapy is used ?

A

In patient that can’t be cured

  • is to produce symptomatic relief not reached after
    surgery.
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5
Q

If we eliminate which of the following from the environment would decrease the risk of cancer most ?

  • Smoking.
  • Alcohol.
  • Environmental pollution caused by factories.
A

Smoking

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6
Q

Cyclophosphamide ?

A
  • (which one is wrong: administered by intrathecal )
  • alkylating agents.
  • Used in cancers.
  • Immunosuppressant.
  • Oral and IV administered.
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7
Q

A 50 yr old female with severe jaundice was diagnosed with pancreatic cancer, u suspect that the tumor is located in which portion of the pancreas?

A

Head

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8
Q

Adjuvant chemo is routinely used in ?

A

Breast cancer ( or colon cancer )

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9
Q

Does a positive pregnancy test indicate cancer ?

A

Yes, some cancers produce HCG (testicular cancer)

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10
Q

Cancer in Poland accounts for ?

A

About 20% of the causes of death

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11
Q

Metastasis in sentinel lymph node require?

A

Selective lymphadenectomy

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12
Q

Most common cancer that kills women ?

A

Breast cancer

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13
Q

Causes of colorectal cancer ?

A

All if the above.

- risk is increased in chronic inflammatory bowel diseases (chron, ulcertive colitis)

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14
Q

Antioncogene who’s mutation are frequently associated with familial occurrence of breast cancer is ?

A

BRCA-1

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15
Q

What is the advantage of palliative care versus standard chemotherapy ?

A

Longer survival

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16
Q

55 yrs old women with breast tumor greater than 3cm without palpable axillary lymph node and distant metastasis, treatment of choice?

A

Lumpectomy And radiotherapy

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17
Q

Treatment that saves a breast in case of breast cancer (BCT) includes?

A

Removal of tumor with a margin of healthy tissue, verification of regional lymphatic system, radiotherapy

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18
Q

Which of the following is not one of the symptoms triad of renal cancer?

A

Weight loss

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19
Q

Q 1. Oncogene can not express in a cell as a result of ?

Q2. AntiOncogene ….

A
  • Ans1. Activation mutation

- Ans2. Inactivation mutation

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20
Q

Which drug is myeloablative ?

A

Busulifan - Alkylating agent (stem cell poison)

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21
Q

Tumor suppressor gene mutation and breast cancer?

A

BRCA-1

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22
Q

The basic cancer screening test for the large intestine is ?

A

Sigmoidoscopy

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23
Q

When esophagus cancer is suspected, first should be done ?

A

Endoscopy

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24
Q

Constipation at an advanced cancer disease may be caused by ?

A
  • All of the above ( regular use of opioids, change of lifestyle and limited intake of foods and drinks, hypercalcemia, hypocalcemia )
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25
Which cancer’s occurrence is NOT associated with smoking?
Colon
26
Stomach carcinoma is found more in ?
Blood group A.
27
Cytostatic drugs ?
Act on cells of one neoplasia but not to other; or some act on many different cancers, and others on just one. It is empirical.
28
Simultaneous heavy smoking and drinking mostly increase the risk of ?
1st: Esophageal cancer. 2nd: Pancreatic cancer.
29
Factors that contribute to a greater risk of of cervical cancer are ?
All of the above: - sexual initiation before 18 - HPV - great number of sexual partners
30
Clinical trial for survival conducted on several centers simultaneously?
The correct answer is: PHASE IV.
31
Describe drawbacks of low-voltage radiotherapy?
Poor penetration
32
Current surgical treatment of stomach cancer hinges on ?
Stomach excision with regional lymph node dissection
33
What is the incidence of cancer dependent on man behaviour ?
50-60%
34
Linear accelerator device used as ?
Megavolt teletherapy
35
Interferon can’t be good effect to cancer because of ?
Genetic variation
36
In a patient with jaundice, in the absence of an obvious cause of extra-hepatic cholestasis in order of following procedures?
1. ERCP 3. Endoscopic ultrasonography 2. Laparotomy
37
Patient reaction to cancer order?
DAA 1. Denying. 2. Anxiety. 3. Adaptation.
38
The most important drug in the treatment of cancer pain is ?
Morphine
39
Interstitial brachytherapy is used for patients treated for ?
Soft tissue sarcoma
40
Clone of hemopoietic cells begin to develop tumor if its cell count will exceed ?
1,000,000
41
The purpose of a palliative chemotherapy in Breast cancer is ?
Prolongation of survival and alleviation of symptoms.
42
Sentinel lymph node excision biopsy in ?
Performed in patients with Melanoma of the skin and is frequently preceded by lymphoscintigraphy.
43
The most common isotope used in HDR brachytherapy?
Iridium 192
44
What does the plateau mean in Kaplan-Meyer curve ?
The longest answer. | - patient survived and cured and has no other diseases
45
Chemotherapy by itself can cure ?
Testicular cancer (also lymphoma)
46
Suggested management if cancer pain us ?
ANS: Treatment of pain on patient request. ** All prevention of pain occurrence.
47
Can you count on a placebo effect in oncology?
NO
48
NOT a standard colorectal screening?
Per rectal examination
49
Women should have the 1st mammography not later than after ?
50 yrs
50
The base for the treatment of the large intestine cancer is ?
Radical therapy
51
Phase 3 trial is evaluated using ?
Survival - effectiveness.
52
Increased level of this parameter is not suggestive of cancer ?
Albumin
53
For which cancer is the liver the 1st and frequently the only location of metastasis?
Colon
54
Nasopharyngeal cancer is associated with etiological factors?
- All of the above ( EBV, genetics, smoking )
55
7 cancer’s warning signs ?
CAUTION * C hange in bowel or bladder habits * A sore that does not heal * U nusual bleeding or discharge * T hickening of lump in breast or elsewhere * I ndigestion or difficulty in swallowing * O bvious change in wart or mole * N agging cough or hoarseness.
56
Historically the most common form of testicle cancer is ?
Cancer from germ cells
57
The most common location of large intestine cancer is ?
Sigmoid colon
58
Which of the following causes cancer resulting from chronic infection ?
- ALL OF ABOVE. (HPV, HBV, H.pylori)
59
The CI for performing modified radical mastectomy?
Inflammatory cancer
60
Breast cancers associated with BRAC-1 mutation have which things in common?
- 40% appear in both breasts. - Histologically malignant. - age 40 ALL of the above
61
** Most common cancer in all human ?
ANS: Skin cancer - Colon cancer
62
The radiologist reporting the MRI scan calls and tells you this looks like a soft tissue sarcoma. You get the patient back, and he keeps asking why you are not simply taking the lump out. You tell him that your plan at this point is to ?
Referral to a local general surgeon
63
Precancerous condition of the large intestine is?
Adenoma
64
Which diagnostic procedure is least useful in differential diagnosis of lung cancer?
Scintigraphy (used to exclude extrathoracic metastasis, not diagnosis)
65
Describe major properties of skin lesions susceptible of being melanoma?
``` A. Asymmetry B. Irregular borders C. Color D. Diameter E. Evolution ```
66
Radiotherapy has major role in the treatment of ?
Rectal cancer
67
Mammography screening recommendations?
*** - At the age of 50-69, every 1-2 yr. - At the age of 40-69, every year .
68
Brachytherapy is ?
Radiation where radiation source is placed inside
69
Taxoids (paclitaxel, docetaxel) are drugs of choice in ?
Ovarian cancer
70
To prevent early vomiting after chemo, it is preferred to use ?
Granisetron
71
Which of the symptoms is not typical for rectal cancer ? - symptoms of obstruction. - Painful urge to pass a stool. - Pencil shaped stool. - Dark colour of stool.
- Dark colour of stool.
72
What is recommended screening for lung cancer in general population?
- There is no accepted screening for lung cancer in general population. ** - spiral-CT currently is the golden standard in diagnosis
73
When to expect neutropenia after cyclophosphamide?
7-14 days
74
What is the 5-year survival rate of Polish males with colon cancer ?
.......
75
Method of choice in radical treatment of stomach cancer is ?
Radical resection with regional lymphadenopathy
76
Hematogenous metastases to liver most often occur in the course of:
Large intestine cancer
77
What is nadir for most of cytostatic drugs ?
Minimal number of leukocytes after chemotherapy that most often falls between 6 and 14 days.
78
Cancer is ?
Malignant tumor of epithelial origin
79
Which cells are not used in trails of cancer immunotherapy?
B-lymphocytes
80
Survival curve - plateau means :
Possibility of cure ( no plateau no cure )
81
Which is not feature of screening ?
Low sensitivity, low specificity
82
40 yr old male with localized SCLC should be treated by ?
Chemotherapy and radiotherapy
83
One of the most common cancers among young men ( aged 20-40 ) is ?
Testicular cancer
84
Screening for lung cancer ?
History of heavy smokers aged 50-85 despite quitting smoking (or been smoking within the past 15 yrs )
85
Percentage of cancer caused by smoking?
** CORRECT ANSWER: 22% 20-30% (22%) ** lecture says 30%
86
The method of choice in the treatment of early rectal cancer is ?
Surgery with creation of anal sphincter
87
Percentage of cancer-related deaths worldwide?
1 in 6
88
Which neoplasm may produce characteristic bone tumors?
Prostate
89
Women with active sexual life have increased risk of ?
Cervical cancer
90
Which tumor marker is typical for ovarian cancer ?
CA 125
91
Which of the following is not a symptom of hypercalcemia ?
Diarrhoea.
92
neoadjuvant ?
Before surgery

Oncology (1 decks)

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