Olfaction Flashcards
(3 cards)
0
Q
What does mucus contain and what makes it?
A
Watery, sugars, proteins, odorant binding protein, salts, antibodies
Replaced every 10 mins
By bowmans glands in supporting cell
1
Q
Olfactory transduction
A
Odorants bind to membrane Golf stimulated Adenylate cyclase activated Forms cAMP Binds to cng cation channels Opens influx of na and ca Ca activated cl channels open Cl efflux Depolarisation Ap
2
Q
Properties of olfactory receptor neurones
A
7tm gpcr
3,4,5 have variable regions
Largest gene family, mostly pseudogenes
Contain 8-20 non motile cilia expressing receptors
Axon is unmyelinated and passes through cribiform plate to olfactory bulb
