Olinger Flashcards
Where are Nissl bodies present
In the cell body and the dendrites
Where are Nissl bodies NOT present?
Axon hillock
Components of Nissl bodies
Free ribosomes, rough ER, and mitochondria
Bipolar neurons
Single axon from either side of cell body
Examples of bipolar neurons
Retina, olfactory epithelium, vestibular, auditory system
Pseudounipolar neuron
Single axon divides a short distance from the cell body
Examples of Pseudounipolar neuron
Sensory ganglia of cranial and spinal nerves
Multipolar neuron
Many dendrites and single long axons
Two kinds of multipolar neurons
Pyramidal and Purkinje cells
Where are pyramidal cells located
Cerebral cortex and have huge dendritic tree
Where are Purkinje cells located
Cerebellar cortex
What makes up the cerebral cortex layers
Gray matter- molecular layer, external granular layer, external pyramidal layer, internal granular layer, internal pyramidal layer, multiform layer
White matter
What makes up the cerebellar organization
Gray matter- molecular layer, Purkinje layer, granular layer
White matter
What happens at the synapse
Electrochemical process where voltage gated sodium channels will propogate signals very fast down the axon and cause depolarization to send the signal to the next cell body
Where are synaptic vesicles located
Located on presynaptic membrane and secrete their contents into the postsynaptic membrane
What are the 4 types of synapses?
Axosomatic, axoaxonic, axodendritic, axospinous
Where are astrocytes located?
Branching cells of the CNS with end-feet extension
End-feet
Ends of the cytoplasmic processes off the astrocytes that cover all blood vessels of CNS, pita mater, and dendrites and cell bodies
Function of end feet
Prevent things from getting where they shouldn’t
Components of the blood brain barrier
Tight junctions, basal lamina, perivascular astrocytes end-feet
Oligodendrocytes
Provide myelination through myelin sheaths and can provide to many axons (whereas in PNS one Schwann cell only provides to single axon)
Myelination CNS vs PNS
CNS- Astrocytic end foot in direct contact with node. Use oligodendrocytes
PNS- Node of Ranvier. Use Schwann cells
Microglia
Macrophages of the CNS
Function of microglia
Release chemoattractant to recruit leukocytes to BBB