OME/Books Flashcards

1
Q

hyperthyroidism then RAIU cold thyroid

A

hashimotos (t4 leaks out then shrivels)

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2
Q

multinodal goiter vs toxic adenoma

A

multiple in multinodal

one in toxic adenoma

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3
Q

woman in health care field, has body image issue, then has hyperthyroidism

A

struma ovarii (check ovary scan)

OR

FACTICIOUS CONSUMPTION T4

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4
Q

rx thyroid storm

A
  • COOL THEM DOWN, IVF
    to help hypotension
    1. beta blocker to reduce autonomic symptoms
      1. PTU/methimazole
      2. steroids (reduce peripheral conversion of T4)
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5
Q

rx multinodal goiter, struma ovarii, toxic adenoma

A

radioactive iodine ablation

PTU/methimazole (thiodamides)

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6
Q

TPO antibodies

A

hashimoto’s or grave’s

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7
Q

MCC hypothyroidism

A

hashimoto’s (get TPO/TSI)

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8
Q

hypo version of thyroid storm

A

myexedma coma (coma, hypotension, hypothermia)

give IVF, blankets, IV T4/T3

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9
Q

recent stressor/surgery/infection, patient develops hypotension, diffuse abdominal pain/tenderness, fever

A

acute adrenal insufficiency

rx with dex/hydrocortisone

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10
Q

risk factors for preterm delivery

A
  • PRIOR HX OF PRETERM
  • multiple gestation
  • hx cervical surgery (i.e. cold knife cone)
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11
Q

imaging to evaluate risk of preterm delivery

A

TVUS for measurement of cervical length

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12
Q

what to give @ 24 weeks to lower risk of preterm delivery

A

progesterone ingestion (maintains uterine quiescene and decreases risk preterm delivery)

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13
Q

what to watch out for in acyclovir

A

crystal induced AKI

watch out for kidney stones that can cause obstruction

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14
Q

patient with nephrotic syndrome develops acute abdominal pain, fever, hematuria

A

RVT

a/w MEMBRANOUS GLOMERULOPNEPHROPATHY

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15
Q

sudden onset acanthosi nigracans OR any explosive onset of sebhorric derm a/w?

A

underlying malignancy

normal acanthosis usually in younger patients, insulin resistant states

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16
Q

anti TPO antibodies a/w with higher risk of?

A

miscarriage

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17
Q

transferrin sautration = ?

A

Iron/TIBC

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18
Q

MCC cervical lymphadenitis in children

A

staph aureus (think bacterial infection)

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19
Q

what to do when you find hyperfunctioning thyroid nodule on biopsy

A

treat hyperthyroid

LOW RISK MALIGNANCY

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20
Q

what to do when non functioning thyroid nodule?

A

RISK FOR CANCER
u/s or go straight to FNA

esp if BIG (>1CM)

21
Q

what to do with non functioning thyroid nodule <1 cm

A

watch and wait

repeat U/s in 6-12 months to see if growing

22
Q

4 types thyroid cancer

A
  1. papillary
  2. follicular
  3. medullary
  4. anaplastic
23
Q

orphan annie nuclei

A

papillary thyroid cancer

(BIG EMPTY NUCLEI) CLEAR CIRCLES

24
Q

which cancer spreads hematogenously

A

follicular (resembles thyroid tissue)

25
Q

RET oncogene

A

MEN 2a/2b syndromes

medullary thyroid cancer

26
Q

parafollicular/C-Cells

A

medullary thyroid cancer

27
Q

pheochromocytoma a/w which kind of thyroid cancer

A

medullary thyroid cancer

28
Q

rx papillary thyroid cancer

A

resection

29
Q

rx painless thyroiditis (palpitations)

A

beta blocker

30
Q

MCC adverse effect inhaled corticosteroid therapy

A

thrush

other (more high dose, less common) - cataracs, adrenal suppression, purpura, decreased growth in children

31
Q

risk of RAI in Grave’s

A

permanent hypothyroidism

32
Q

pathophys sickle cell disease SCD

A

glut -> val subs on chrome 16 causing mutated B2 -> HgB SS

33
Q

a2Y2 (gamma)

A

HgbF

34
Q

GI side effect SCD

A

hemolysis -> elevated unconj bili -> pigmented gallstones -> may need chole later

smear shows sickles? = CRISIS

35
Q

how to help determine if SCD patient is in crisis?

A

compare to baseline bili, Hgb, retics

36
Q

Prophylaxis children with SCD

A

prophylactic PCN until age 5

37
Q

bone effects SCD

A

avascular necrosis
OSTEO (with salmonella)

but overall most common is staph

38
Q

acute chest components (3)

A

chest pain
SOB
PULMONARY EDEMA

39
Q

besides acute chest/pain crisis what other acute finding in acute sickle (2)

A

priapism

STROKE/FND

40
Q

rx acute crisis SCD

A

IVF, O2, pain control

41
Q

prophylaxis acute pain crisis

A

HYDROXYUREA (increase HgBF)

42
Q

HgbSC vs HgBSS

A

SC - not disease, trait, minor baseline anemia, one recessive, counsel pregnancy
SS - full on disease

43
Q

HgB0

A

worst SCD

44
Q

ECG finding hypocalcemia

A

QTC prolongation

45
Q

how does pregnancy affect thyroid levels

A

bHCG INCREASES thyroid hormone
estrogen increases thyroid binding globulin
(increase in TOTAL not free T4)

ALL TO HELP KEEP UP WITH INCREASE METABOLIC DEMAND

46
Q

hospitalized patient TPN develops hypophos, hypok, hypomag…develops arrythmias, cardiopulmonary failure

A

refeeding syndrome
esp dangerous in anorexia
INCREASED INSULIN causes this

47
Q

how can lymphoma affect Ca

A

can cause incerased 1,25 vit D to increase Ca absorption, lower PTH, increase vit D (part of hypercalcemia of malignancy)

48
Q

4 characterisitcs of MEN 2B

A

neuromas
medullary thyroid
pheochromocytoma
MARFANOID HABITUS

49
Q

primary adrenal insufficiency vs central

A

primary - usually autoimmune, low cortisol, high ACTH, low aldosterone
central - usually due to chronic glucocorticoid, low ACTH, low cortisol, NORMAL ALDOSTERONE