OME - Neuro Flashcards

(57 cards)

1
Q

Carbidopa MOA?

A

Prevents conversion of L-dopa —> Dopamine

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3
Q

What makes up fiorcet?

A

BAC
Butalbital
Acetaminophen
caffeine

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4
Q

Pt w/Alzheimer’s disease what goes 1st? Then what?

Treat how?

Die when?

A

Memory, then dementia

AChE-I’s: tacrine or donepezil

5-10 years, bc of PNA

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5
Q

Myoclonic seizure treated with what?

Pt presents how?

A

Valproate

Jerkey muscle

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6
Q

Pt that has vertigo, N/V, hearing sx 4 weeks post URI has what?

Treat how?

A

Labyrinthitis/vestibular neuritis

Steroids

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9
Q

What meds are used to treat young, functional people with Parkinson’s disease?

Names?

A

Dopamine agonists

Ropinirole, Pramipexole

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10
Q

What is the primary sx of MS?

If suspected get what?
See what?

A

Blurry vision/Diplopia from optic neuritis

MRI
Periventricular plaques, multiple lesions, lesions on corpus callous

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12
Q

How to treat M.G. If it is compromising life?

Refractory disease treated how?

A

IVIG or plasmapheresis

Prednisone, azathioprine

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14
Q

What signs indicate death?

A

Rigor Mortis

Lividity (dark blue pooling of venous blood)

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15
Q

What is the confirmatory test for Guillain-Barre?

What etiology>

A

EMG or NCV

Diarrhea illness or flu vaccine

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17
Q

Atonic seizure treated with what?

Pt is like what?

A

Valproate

Floppy head, wears helmet bc they fall over

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18
Q

NPH presents how?

What sx 1st?

Dx how?

Treat how?

A

Wet, wobbly, wacky

Motor

CT or MRI

VP shunt or serial LPs

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20
Q

What are examples of Thrombotic stroke?

A

CAD/PVD
Atherosclerosis
HTN

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21
Q

Pt that has Persistent Vegetative State has what signs?

A

Flat EEG but opens eyes

+ Caloric test

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22
Q

What drugs used for chronic management of MS?

A

IFN
Fingolimod
Glatiramer

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23
Q

What are the 4 classic pts at risk for stroke?

A

All have FND

1) HTN, DM, smoker, Old
2) AFib, valve
3) young women w/neck pain
4) thunderclap HA

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24
Q

Central causes of dizziness include what?

A
CVA
Post fossa tumor
MS
Meds
Abscess
Migraines
Seizures
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25
Q

Pt that has brain death has what sx?

A

Absent EEG

Absent brain stem reflexes —> No COWS or corneal reflex

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26
Q

What is always preserved in normal aging?

What indicates dementia?

A

Language comprehension and vocab

MMSE score < 22

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27
Q

What does the CSF show in guillon Barre show?

What is contraindicated?

A

Inc Protein, VERY FEW cells

Steroids

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28
Q

What does the EMG of lambert-Eaton look like?

MG?

A

Weak then gets stronger

Reversed

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33
Q

Old pt w/back pain that has point tenderness and vertebral stepoff has what?

A

Compression fracture

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34
Q

Pt has no cerebrum, what does the COWS test show?

A

Eyes move to cold water but NO nystagmus

35
Q

Lambert-Eaton has what?

MOA?

What sx?

A

Abs against Pre-synaptic Ca channels

Inhibits release of ACh-vesicles

Prox muscle weakness that improves with use

36
Pt w/M.G. Has what physical symptoms?
Difficulty swallowing, chewing, fatigibility over the course of the day that is relieved by rest
40
Pt in coma, what is the work up? What is in the coma cocktail?
CMP, CT, LP, EEG B1, D50, O2, Naloxone
41
When can you give tPA?
Present w/in 4.5 hours of symptom onset
43
Pt that has pain in back that is symmetric, belt-like and achey, what origin? Treatment? If it doesn’t work do what next?
MSK pain NSAID + exercise XRay then MRI after 4-6 weeks of NSAID trial
45
Spinal stenosis has what sx? Gets better when?
Leg and butt pain Flexion, exercise
46
Elderly male w/shooting lightning back pain w/no inciting event has what? Work up? Tx?
Osteophyte XRay then MRI Surgery
47
Pt that has vertigo, rotary nystagmus on head movement that is < 1 minute has what? Caused by what?
BPPV Otolith
50
What is the 1 time that you do NOT need a heparin bridge when giving warfarin?
AFib
52
Treatment for meneire’s?
Diuretics and low salt diet
57
Treatment for M.G. Is what? How to diagnose? Confirm with what?
Pyridostigmine (AchE-I) Serum ABs to ACh-receptor EMG
58
What sign indicates the brain cortex is dead?
Blurring of gray-white matter junction
59
Pt w/lightning or shooting pain down leg that is worse w/hip flexion, movement, cough, or activity has what? Tx?
Disc herniation Neurosurgery > conservative at 6 months
62
Mask like expressionless face think what? What other sx?
Parkinson’s ``` TRAP Tremor - pill rolling resting Rigidity Akathesia Parkinson’s like gait ```
63
Pt that has b/L, vice-like pain that radiates from the front to the back/neck has what? Tx?
Tension HA NSAID
65
Parkinson’s pt with tremor only, treat how?
Benztropine (ACh-R antagonists)
69
What meds to give Parkinson’s pt when levodopa/Carbidopa begins to fail?
COMT - Capones MAOB - selegiline
70
What is trigeminal autonomic cephalgia? What sx? Work up how? Treat how? Prophylax how?
Cluster HA Rhinorrhea, lacrimation, conjunctival injection, Horner’s MRI Oxygen 1st, then sumatriptan Verapamil
71
How medically treat Migraines? Prophylax with what?
Tristan or Ergot (careful in CAD) Propranolol, verapamil/diltazem, or valproate/topiramate
72
Pick’s disease presents how?
Personality goes 1st, hypersexual/aggressive
74
Loss of pain/temp and motor fx that is B/L has what going on?
Ant. Spinal artery occlusion
75
How does vascular dementia present? Pt has what RFs? Image with what?
Step-wise decline w/each stroke HTN, DM, CVA MRI
79
Pt w/suspected cord compression what is 1st step? Then what? Then what?
Dexamethasone Xray MRI (if xray Neg)
81
Pt complains of intermittent low back pressure relieved by farting or shitting has what?
Visceral organ pain
83
What are the red flags in a HA pt?
New HA > 50 Sudden crescendo HA Fever + HA FND
85
What is the mainstay of stroke tx? If allergy use what? If 2nd stroke use what?
ASA Clopidogrel ASA + Dipyridamole
86
Fever + HA + FND = ?? Work up how? Treat?
Abscess CT Drain, Abx
87
IIH has what symptoms? Pt is what? Imaging looks like what? Treat how?
Inc ICP, papilledema Women, obese, on OCPs negative CT, LP w/Inc pressure Acetazolamide, VP shunt/LPs
88
What are the 3 etiologies of stroke?
Ischemic - embolus Ischemic - thrombosis (plaque rupture) Hemorrhagic
90
What is the treatment for old (>70) or non functioning pts with Parkinson’s? Which crosses the BBB?
Levodopa-Carbidopa Levodopa
93
What is the algorithm of aborting a seizure?
IV Benzo (lorazepam/Diazepam) Fosphenytoin Intubate —> Midazolma and propofol Phenobarbital
94
Pt that is having a hemorrhagic stroke with high BP give what?
IV esmolol
95
What are examples of an emboli stroke?
AFib Carotid Stenosis IE
97
Describe an intention tremor
Absent at rest, gets WORSE the closer it gets to the target