Oncological emergencies Flashcards Preview

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Flashcards in Oncological emergencies Deck (15)
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1
Q

Type of pain associated with spinal cord compression?

A

Pain in spine/radicular band-like distribution

Worse on coughing/straining

2
Q

Symptoms of malignant cord compression? (5)

A
Back pain
Leg weakness
Altered sensation
Urinary retention
Constipation/faecal incontinence
3
Q

Investigation to confirm diagnosis in malignant cord compression?

A

Urgent MRI of spine

4
Q

Interim treatment of malignant cord compression?

A

Dexamethasone (16mg IV loading dose, 8mg oral bd)

5
Q

Definitive treatment of malignant cord compression? (2)

A

Surgery

Radiotherapy (mainstay of treatment)

6
Q

Swelling of neck/face/arms + distended veins + SOB

A

Superior vena cava obstruction

7
Q

Signs of SVCO? (3)

A

Puffy neck, neck veins don’t collapse when pressed
Conjunctival injection
Sedation/sleepiness

8
Q

Possible causes of SVCO? (4)

A

Clot
Foreign body e.g. line
Tumour in vessel
Extrinsic compression from mass

9
Q

Investigations for SVCO?

A

CXR, venogram, CT chest

10
Q

SVCO as a result of extrinsic compression can be treated with?

A

Steroids (widely used but little evidence)
Radiotherapy
Chemotherapy
Stenting (relieves compression but doesn’t treat cause)

11
Q

Causes of hypercalcaemia in malignancy? (3)

A

Parathyroid hormone related peptide secretion by tumours

Local bone destruction

Production of vitamin D analogues by tumour

12
Q

Which group of tumours are especially prone to secreting Vitamin D analogues?

A

Lymphomas

13
Q

Hypercalcaemia and no known malignancy- investigation?

A

Myeloma screen

urea and electrolytes, creatinine, serum/urine electrophoresis

14
Q

Treatment of malignant hypercalcaemia?

A

IV fluids

IV bisphosphonates

15
Q

Why is it important that patients are rehydrated prior to bisphosphonates?

A

Can cause renal failure