Oncology Flashcards

(42 cards)

1
Q

Swelling - Benign

A

Tumor

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2
Q

New growth

A

Neoplasia

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3
Q

Study of tumors or neoplasia

A

Oncology

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4
Q

Maturation; extent to which neoplastic parenchymal cells resemble the corresponding normal parenchymal cells- morphologically and functionally

A

DIFFERENTATION

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5
Q

Poorly differentiated cells = ?

A

Malignant - malayo itsura sa normal

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6
Q

Well differentiated cells = ?

A

Benign - malapit itsura sa normal

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7
Q

Lack/loss of differentiation associated w morphologic changes

A

Anaplasia

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8
Q

Variation in size and shape
A. Dysplasia
B. Neoplasia
C. Pleomorphism
D. Anaplasia

A

Pleomorphism

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9
Q

Loss of Polarity, disturbed orientation = ?

A

Meaning tissues and cells (anaplastic glands) are disorganized

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10
Q

Loss in uniformity & architectural orientation of cells, pre-cancerous stage, reversible, disordered growth and often occurs in metaplastic epithelium.

A. Dysplasia
B. Neoplasia
C. Pleomorphism
D. Anaplasia

A

Dysplasia

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11
Q

Abnormal mass of tissue

A. Dysplasia
B. Neoplasia
C. Pleomorphism
D. Anaplasia

A

Neoplasia

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12
Q

Growth exceeds and uncoordinated with that of the normal tissue, autonomous, and clonal-arise from single cell that incurred genetic damage

A

NEOPLASIA

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13
Q

BENIGN OR MALIGNANT
Remain localized

A

Benign

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14
Q

BENIGN OR MALIGNANT
Cause death

A

MALIGNANT

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15
Q

BENIGN OR MALIGNANT
Amenable to surgical removal

A

BENIGN

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16
Q

BENIGN OR MALIGNANT
Relatively innocent and pt. Generally survives

A

BENIGN

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17
Q

BENIGN OR MALIGNANT
Invade and destroy adjacent structures

18
Q

BENIGN OR MALIGNANT
Cancer

19
Q

BENIGN OR MALIGNANT
Rapid erratic pace of rate of growth

20
Q

BENIGN OR MALIGNANT
Local invasion - usually absent

21
Q

BENIGN OR MALIGNANT
Poorly differentiated / anaplastic

22
Q

Nuclear cytoplasmic ratio that is anaplastic
A. 1:1
B. 1:6
C. 1:3
D. All of these

23
Q

Genes that promote autonomous growth

24
Q

normal cellular counterpart

A

Protoncogenes

25
products of genes without regulatory function
Oncoproteins
26
Breaks to cell proliferation; these genes lead to failure of growth inhibition, another fundamental hallmark of carcinogenesis
Tumor Suppressors
27
“Governor of cell cycle”
RB gene
28
“Guardian of the genome”
P53 protein
29
Mutation associated with retinoblastoma and osteosarcoma
RB GENE
30
Stops neoplastic transformation by Cell cycle arrest (quiescence and senescence) initiation of apoptosis
P53
31
Carcinoma = ?
Epithelial tissue
32
Sarcoma = ?
Connective tissue
33
Lymphoid tissue - ? Hematopoietic tissue - ?
Lymphoma Leukemia
34
T OR F “Oma” connotes BENIGN, except seminoma, lymphoma, malanoma, hepatoma
TRUE
35
Infection with HTLV increases the risk for
Lymphoma
36
When anaplastic cels have disorganized arangement this si described as A. loss of polarity B. metaplasia C. apoptosis D. dysmorphism
Loss of polarity
37
This organism si associated with development of gastric carcinoma. A. Entamoeba histolytica B. Ascaris lumbricoides C. Salmonella typhi D. Helicobacter pylori
Helicobacter pylori
38
Which of the folowing tumor si malignant? A. Fibroma B. hepatoma C. adenoma D. leiomyoma
Hepatoma
39
Paraneoplastic syndromes present significant problems because htey A. may destroy tissues B. both choices C. elaborate abnormal products which maybe harmful D. neither choice
Both choices
40
A form of primary prevention of cancer is A. vaccination B. both C. diet modification D. Neither
Both
41
The UV ray exposure with greater risk for skin cancer is?
UV B
42
degree of differentiation of the tumor cells and the number of mitosis
Grading