Oncology Flashcards
(29 cards)
The single most important prognostic factor in ALL
Trearment
Three most important predictive factors in ALL:
Age
Initial leukocyte count
Speed of response to treatment
Three most important predictive factors in ALL:
Age
Initial leukocyte count
Speed of response to treatment
This phase in cancer management is designed to eradicate the leukemic cells
Remission Induction in 4 Weeks
Phase in CA management that allows recovery from the prior intensive therapy
Delayed Intensive/Intensifocation phase
The major impediment to a successful outcome in ALL
Relapse
Patients with high WBC are prone to this condition once therapy starts
Tumor lysis syndrome
Hyperurecemia, hyperkalemia, hyperphosphatemia and hypocalcemia
Tumor lysis syndrome
These clinical findings are often seen on this condition:
Painless, firm lymphadenopathy often confined in 1 to 2 lymph node areas (supraclavicular and cervical nodes)
Hodgkin Lymphoma
These clinical findings are often seen on this condition:
Painless, firm lymphadenopathy often confined in 1 to 2 lymph node areas (supraclavicular and cervical nodes)
Hodgkin Lymphoma
Fever (3 Days)
Drenching Night Sweats
Unintentional weight loss of 10% or more within 6 months
B Symptoms in Lymphoma
Fever (3 Days)
Drenching Night Sweats
Unintentional weight loss of 10% or more within 6 months
B Symptoms in Lymphoma
Hallmark of Hodgkin Lymphoma:
Reed-Sternberg Cells
Headache, nausea and vomiting, papilledema
Midline or infratentorial tumors
This syndrome is seen with pineal region tumors manifested as:
Paresis of upward gaze, pulillary dilatation not reactive to light, nystagmus and eyelid retraction
Parinaud Syndrome
CSF measurements of Beta HCG and alpha FetoCHOn helps to diagnosis this condition
Germ Cell Tumors of the CNS
The classic site for this tumor is usually at the cerebellum and there are Rosenthal fibers (condensed glial filaments) seen:
Astrocytomas
This condition often presents as children with endocrine abnormalities such as growth failure and delayed sexual maturation
Craniopharyngioma
These are embryonal cancers of the peripheral sympathetic nervous system
Neuroblastomas
These are embryonal cancers of the peripheral sympathetic nervous system
Neuroblastomas
Small round blue cell tumors:
Neuroblastoma
Rhabdomyosarcoma
Ewing Sarcoma
Non-Hodkin Lymphoma
Small round blue cell tumors:
Neuroblastoma
Rhabdomyosarcoma
Ewing Sarcoma
Non-Hodkin Lymphoma
Horner Syndrome
Unilateral ptosis,myosis and anhidrosis
Assocm with thoracic and cervical tumors
Incidental discovery of an asymptomatic abdominal mass
Wilms Tumor