Oncology

Question 1

AFP

Answer 1

Liver cancers and germ cell

Question 2

b-hCG

Answer 2

Choriacarcinoma

Germ cell

Question 3

BRCA1 and 2

Answer 3

Ovarian cancer

Breast cancer

Question 4

BCR-ABL and alternative name

Answer 4

CML!!, AML, ALL

Philidelphia chromosome

Question 5

CA15

Answer 5

Breast cancer

Question 6

CA19

Answer 6

Pancreatic, gallbladder, bile duct, gastric

Question 7

CA125

Answer 7

Ovarian

Question 8

Calcitonin

Answer 8

Medullary thyroid

Question 9

CEA

Answer 9

Colorectal

Question 10

CD20

Answer 10

NHL

Question 11

EGFR mutation analysis

Answer 11

NSCLC

Question 12

Oestrogen/Progesterone receptor

Answer 12

Breast

Question 13

Fibrin/fibrinogen

Answer 13

Bladder

Question 14

HE4

Answer 14

Ovarian

Question 15

HER2

Answer 15

Breast
Gastric
GO junction adenocarcinoma

Question 16

Immunoglobulins

Answer 16

MM

Question 17

KRAS mutation analysis

Answer 17

Colorectal

NSCLC

Question 18

LDH

Answer 18

Lymphoma
Leukaemia
Melanoma
Germ cell
Neuroblastoma

Question 19

PSA

Answer 19

Prostate

Question 20

Thyroglobulin

Answer 20

Thyroid

Question 21

Philadelphia chromosome

Answer 21

t9:22, which results in fusion gene BCR-ABL

Question 22

Rituximab

Answer 22

Anti-CD20 monoclonal antibody, B-cell lymphoma

Question 23

Trastuzumab alternative name and use

Answer 23

Herceptin, monoclonal antibody that prevents her2 function, biologic used in Breast Ca

Question 24

Tamoxifen

Answer 24

Hormonal anti-oestrogen used in oestrogen receptor positive breast cancer

Question 25

Two main immunotherapy drugs

Answer 25

Interferon | Interleukin

Question 26

Two main delivery modes in radiotherapy

Answer 26

Teletherapy | Bracytherapy

Question 27

3 preferred opioids in CKD

Answer 27

Fentanyl Buprenorphine Alfentanil

Question 28

Chemo drug lung fibrosis is most serious side effect

Answer 28

Bleomycin

Question 29

Two chemo drugs often cause peripheral neuropathy

Answer 29

Vincristine | Cisplatin

Question 30

Chemo drug haemorrhagic cystitis

Answer 30

Cyclophosphamide

Question 31

Earliest and most common syx of MSCC

Answer 31

Back pain

Question 32

What is a PET scan measuring

Answer 32

Glucose uptake

Question 33

Chemo drug cardiomyopathy

Answer 33

Doxyrubacin

Question 34

5 key bony mets

Answer 34

``` Breast Bronchus Thyroid Kidney Prostate ```

Question 35

4 tumours which commonly metastasise to lung FIRST

Answer 35

Breast Bronchus Thyroid Kidney