Oncology

Question 1

Multiple myeloma features

Answer 1

CRAB-I
Calcium raised
Renal injury (high Cr and Urea)
Anaemia
Bones (sclerosis —> pathological fracture)
Infection

Question 2

What is the tumour marker for ovarian cancer?

Answer 2

CA 125

Question 3

What is the tumour marker for Breast cancer?

Answer 3

Ca 15-3

Question 4

What is Ca 19-9 a tumour marker for?

Answer 4

Pancreatic cancer

Question 5

What does a high PSA indicate?

Answer 5

Prostate cancer, BPH or other prostate problems.

Question 6

What is the tumour marker for colorectal cancer?

Answer 6

CEA

Question 7

What is Alpha-feto protein (AFP) a marker of?

Answer 7

HCC (Hepatocellular Carcinoma) or teratoma

Question 8

What is S-100 a marker for?

Answer 8

Melanoma or Schwannoma.

Question 9

What is Bombesin a marker for?

Answer 9

SCLC, Gastric Ca, Neuroblastoma

Question 10

What type of cancer can cause Cushing’s as a paraneoplastic syndrome?

Answer 10

Small cell lung cancer

Question 11

What type of cancer is associated with gynaecomastia?

Answer 11

Adenocarcinoma of the lung

Question 12

What do squamous cell lung cancers secrete that causes hypercalcaemia?

Answer 12

Parathyroid hormone-releasing hormone