Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Team decks > Open trials - past backup > Flashcards

Open trials - past backup Flashcards

(53 cards)

Start Studying
1
Q

Which cancer is eligible for SARC 032?

A

soft tissue sarcoma of the extremity (resectable)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the drug studied and route of admin - SARC 032?

A

Pembro infusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Is it comparator controlled, placebo controlled, etc. - SARC 032?

A

open label comparator - XRT/surgery (SOC) vs Neoadj. Pembro+XRT/Surgery/Adj. Pembro

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

SARC 032: Sponsor, PI, CRC - SARC?

A

Sarcoma Alliance (drug provided by Merck), Mo, Melanie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Which cancer is eligible for GemAcsorbate?

A

Unresectable soft tissue and bone sarcoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the drug studied and route of admin - GemAscorbate?

A

Per 28 day cycle: Ascorbate - 6 infusions, Gemcitabine - 3 infusions

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Is it comparator controlled, placebo controlled, etc. - GemAscorbate?

A

refer to protocol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

GemAscorbate: Sponsor, PI, CRC - SARC?

A

IIT, Mo (Monga), Melanie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Which cancer is eligible for City of Hope?

A

Leiomyosarcoma and other soft tissue sarcomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the drug studied and route of admin - City of Hope?

A

In 28 day cycle: Temozolomide chemo infusions day 1 - 5 + daily oral Cabozantinib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Is it comparator controlled, placebo controlled, etc. - City of Hope?

A

single arm: Temozolomide chemo (SOC) + daily oral Cabozantinib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

City of Hope: Sponsor, PI, CRC?

A

City of Hope, Mo, Melanie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Which cancer is eligible for BOAST?

A

bone & soft tissue sarcoma (CDK)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the drug studied and route of admin - BOAST?

A

Daily oral Abemaciclib 2x per day

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Is it comparator controlled, placebo controlled, etc. - BOAST?

A

single arm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

BOAST: Sponsor, PI, CRC?

A

Medical College of Wisconsin, Mo, Melanie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

MK3475: Sponsor, PI, CRC?

A

Merck, Mo, Melanie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Exelixis: Sponsor, PI, CRC?

A

Exelixis, Zakharia, Melanie

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Genentech: Sponsor, PI, CRC?

A

Genentech, Mo, Teena

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

C4: Sponsor, PI, CRC?

A

C4, Mo, Teena

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

TTI-621: Sponsor, PI, CRC?

A

Trillium, Mo, Teena

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

GIST-PEAK: Sponsor, PI, CRC?

Study These Flashcards
A

Cogent Biosciences, Mo, Melanie

23
Q

NeoDream/Philogen: Sponsor, PI, CRC?

Study These Flashcards
A

Philogen, Mo, Melanie

24
Q

Fight209: Sponsor, PI, CRC?

Study These Flashcards
A

Incyte, Mo, Teena

25
Which cancer is eligible for MK3475?
"Advanced tumors" - extension trial, eligible if enrolled in prior pembro trial
26
Which cancer is eligible for Exelixis?
nonresectable advanced melanoma
27
Which cancer is eligible for Genentech?
NRAS-Mutant advanced melanoma
28
Which cancer is eligible for C4?
synovial sarcoma (and others) - SMARCB1 perturbed
29
Which cancer is eligible for TTI-621?
high grade leiomyosarcoma (not amenable to curative tx)
30
Which cancer is eligible for GIST-PEAK?
GI stromal tumors (unresectable or mets)
31
Which cancer is eligible for Neodream/Philogen?
melanoma (not yet reviewed)
32
Which cancer is eligible for FIGHT-209?
recurrent glioblastoma or other CNS (FGFR1-3)
33
What is the drug studied and route of admin - MK3475?
Pembro infusion Q3W (& combos based on prior studies)
34
What is the drug studied and route of admin - Exelixis?
Pembro infusion Q3W & oral Cabozantinib daily
35
What is the drug studied and route of admin - Genentech?
oral Belvarafenib, BID; oral cobimetrinib daily; Atezolizumab infusion Q4W
36
What is the drug studied and route of admin - C4?
oral CFT8634
37
What is the drug studied and route of admin - TTI-621?
Q3W: Doxirubicin chem infusion; TTI-621 infusion
38
What is the drug studied and route of admin - GIST?
oral sutinib qd; CGT9486 (bezuclastinib) qd (without food)
39
What is the drug studied and route of admin - Neodream/Philogen?
(not reviewed yet)
40
What is the drug studied and route of admin - Fight-209?
oral Pemagatinib daily, 2 weeks on 2 weeks off
41
Is it comparator controlled, placebo controlled, etc. - Fight-209?
single arm
42
Is it comparator controlled, placebo controlled, etc. - NeoDream/Philogen?
(not yet reviewed)
43
Is it comparator controlled, placebo controlled, etc. - GIST?
comparator: Sutinib vs sutinib + bexuclastinib
44
Is it comparator controlled, placebo controlled, etc. - TTI-621?
?
45
Is it comparator controlled, placebo controlled, etc. - C4?
single arm
46
Is it comparator controlled, placebo controlled, etc. - Genentech?
comparator: Belvararafenib vs Bel+Cobimetinib vs. Bel+Cob+atelolizumab
47
Is it comparator controlled, placebo controlled, etc. - Exelixis?
single arm?
48
Is it comparator controlled, placebo controlled, etc. - MK3475?
extension trial - single arm
49
Name Teena's trials
Genentech, TTI-621, C4, FIGHT-209
50
Name sarcoma trials:
SARC 032, GemAscorbate, City of Hope, BOAST, TTI-621, C4, GIST
51
Name melanoma trials:
MK3475-587, Exelixis, Genentech, Neodream/Philogen
52
Which one is Zakharia's trial?
Exelixis
53

Team decks (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions