Ophthalmology Flashcards

(41 cards)

1
Q

What is cataracts?

A

The opacification of the crystalline lens.

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2
Q

What are the risk factors for cataracts?

A
Age > 65 years
Smoking
Long term UV exposure
Diabetes Mellitus
Eye trauma 
Long term ocular corticosteroid use
FHx of congenital cataract or congenital toxins
Uveitis
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3
Q

What is the aetiology for cataracts?

A
The normal ageing process
Trauma
Metabolic disorders (hereditary or acquired)
Medications
Congenital problems
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4
Q

What is the epidemiology for cataracts?

A

Cataracts accounts for 51% of reversible blindness worldwide

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5
Q

What are the presenting symptoms of cataracts?

A

Gradual decrease in vision over many years
-DM: relatively sudden reduction in vision
Blurred or cloudy vision
Washed out colour vision
Glare- particularly driving at night
Inadequate glasses prescription

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6
Q

What are the signs of cataracts on physical examination?

A

Reduced visual acuity

Defects in the red reflex (seen on ophthalmoscopy)

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7
Q

What are the appropriate investigations for cataracts?

A

Dilated fundus examination: fundus and optic nerve normal
Intra-ocular pressure: normal (or may be elevated if associated with glaucoma)
Glare vision test: significant cataract- reduced visual acuity under the conditions of glare stress*
Slit lamp examination of the anterior chamber: cataract visible

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8
Q

What is conjunctivitis?

A

Inflammation of the lining of the eyelids and eyeball

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9
Q

What is the aetiology of conjunctivitis?

A
Caused by:
Bacteria
Viruses
Allergic or immunological reactions
Mechanical irritation
Medicines

Bacterial and viral conjunctivitis is highly contagious

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10
Q

What are the risk factors for conjunctivitis?

A
Exposure to infected person
Infection in one eye
Environmental irritants 
Allergen exposure
Mechanical irritation 
Chronic contact lens useful
Camps/ swimming pools
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11
Q

What are the presenting symptoms of conjunctivitis?

A
Watery discharge (viral)
Ropy/ mucoid discharge, itching (allergic)
Purulent discharge (bacterial)
Eyelids stuck together in the morning (bacterial and viral)
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12
Q

What are the signs of conjunctivitis on physical examination?

A

Tender pre-auricular lymphadenopathy (more common in viral than bacterial infection)
Conjunctival follicles- round collections of lymphocytes

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13
Q

What are the appropriate investigations for conjunctivitis?

A

1st line:
Rapid adenovirus immunoassay- 2 visible lines equal positive
Others:
Cell culture/ Gram stain/ PCR- isolate viral or bacterial strains, amplify DNA

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14
Q

What is glaucoma?

A

Optic neuropathy with visual field loss and blindness usually associated with sustained raised intra-ocular pressure (ocular hypertension = IOP > 21 mmHg)

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15
Q

What is the aetiology for glaucoma?

A

Primary causes: Acute closed-angle glaucoma (ACAG), primary opened-angle glaucoma (POAG), chronic closed-angle glaucoma.
Secondary causes: Trauma, uveitis, steroids, rubeosis iridis (diabetes, central retinal vein occlusion)
Congenital: Buphthalmos (enlargement of the eyeball), other inherited ocular disorders

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16
Q

What is the uvea?

A
Vascular coat of the eyeball and lies between the sclera and retina.
Composed of 3 parts:
-Iris
-Ciliary body
-Choroid
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17
Q

Describe the anterior chamber

A

Between the cornea and lens and filled with clear aqueous fluid which is nutrient-rich

18
Q

What is the role of the ciliary body?

A

Secrete aqueous fluid into the anterior chamber

19
Q

What structure drains the aqueous fluid out of the eye?

A

Trabecular meshwork through the canal of Schlemm

20
Q

What is normal intraocular pressure?

21
Q

What is Primary Open Angle Glaucoma?

A

The most common form of glaucoma- “trabecular meshwork dysfunction”

22
Q

What is closed angle glaucoma?

A

Where increased ocular pressure pushes the iris/lens complex forwards, blocking the trabecular meshwork which drains the aqueous fluid- exacerbates the problem increasing pressure further

Can be acute or chronic

23
Q

What is the epidemiology for glaucoma?

A

Prevalence 1 % in over 40 years, 10 % in over 80 years (POAG).
Third most common cause of blindness worldwide.

24
Q

What are the presenting symptoms in acute closed angle glaucoma?

A

Painful red eye
Vomiting
Impaired vision
Haloes around lights.

25
What are the presenting symptoms in primary open angle glaucoma?
Usually asymptomatic- peripheral visual field loss may be noticed
26
What are the signs of acute closed angle glaucoma on physical examination (slit lamp)?
``` Red eye Hazy cornea Loss of red reflex Fixed and dilated pupil Eye tender and hard on palpation Cupped optic disc Visual field defect - arcuate scotoma = arc shaped visual defect near blind spot Moderately raised IOP. ```
27
What are the risk factors for acute closed angle glaucoma?
``` Small eye (hypermetropia) Narrow angle at trabecular meshwork ```
28
What are the signs of primary open angle glaucoma on physical examination (slit lamp)?
Usually no signs. | Optic disc may be cupped.
29
What are the appropriate investigations for glaucoma?
-Goldmann tonometry: measure ocular pressure (normal 15 mmHg, POAG 22–40 mmHg, ACAG > 60 mmHg) -ophthalmoscopy: measure cup to disc ratio -*Gonioscopy: definitive test for angle closure glaucoma (trabecular meshwork is not visible in angle closure, because the peripheral iris is in contact with it)
30
What is uveitis?
Inflammation of one or all parts of the uvea
31
What is the anterior uvea composed of?
The iris and ciliary body
32
What can irritation of the anterior uvea cause?
Acute painful symptoms and photophobia
33
What risk can inflammation of the posterior uvea cause?
Painless visual loss
34
What is the aetiology of uveitis?
Divided into idiopathic, infectious, and non-infectious causes.
35
What are some of the infectious causes of uveitis?
``` Herpes simplex virus HIV Lyme disease Syphilis TB ```
36
What are some of the non-infectious causes of uveitis?
``` Inflammatory bowel disease Autoimmune disorders Sarcoidosis Multiple sclerosis Eye trauma ```
37
What are the risk factors for uveitis?
Inflammatory diseases of the joints, bowels or skin | History of ocular trauma and high risk occupation
38
What is the epidemiology of uveitis?
Can affect individuals of any age, sex, or geographical location without preference
39
What are the presenting symptoms of uveitis?
``` Pain (anterior uveitis) Decreased vision (blurred, visual field loss) Tearing Photophobia Eye redness without discharge (anterior) ```
40
What are the signs of uveitis seen on physical examination?
Flare: the hallmark of anterior uveitis, light scattering within the anterior chamber of the eye Constricted/ non-reactive pupil (anterior) Synchiae: seen during acute inflammation (iris adherence to the cornea in anterior or lens in posterior) Keratin precipitates: lymphocyte aggregation on the conceal endothelium Optic disc swelling and retinal haemorrhages (posterior uveitis)
41
What are the appropriate investigations for uveitis?
1st line investigation: clinical diagnosis (history, symptoms and examination) Others: -FBC (elevated WCC in infection) -ESR/ CRP (inflammation) -HLA-B27 positive for patients with uveitis -antibodies for infectious causes