Opiods Flashcards Preview

Pharmacology I > Opiods > Flashcards

Flashcards in Opiods Deck (13)
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1
Q

MoA for Opioid agonists

A

Activation of opiod Gi/o coupled receptors

Inhibit neurotransmission

2
Q

What are Schedule I, II, III, IV drugs

A

I- heroin
II: Morphine
III: Buprenorphine
IV: Butorphanol, tramadol

3
Q

Main pharacological effect from opioids?

A

analgesia
some sedation
antitussive
respiratory depression

4
Q

When should you not use opiods?

A

head injuries
decreased GI motility
Cardiac/Respiratory Dz, Renal failure

5
Q

Full u agonists

A

Morphine
Hyromorphone
Fentanyl
Carfentanil

6
Q

Difference between Morphine and Hydromorphine

A

Hydromorphine causes less histamine release

Morphine is used in epidurals

7
Q

Fentanyl

A

full u agonist

fast onset, short duration, good for CRI, transdermal

8
Q

Carfentanil/Etorphine

A

way more potent than morphine

Used in wild life darting

9
Q

Buprenorphine

A

partial u agonist

good as transmucosal for crazy ass cats

10
Q

Butorphanol

A

k Agonist and u ANTagonist
better for visceral pian
analgesial lower ceiling effect than mu agonists
common opiod for equines
can be used in small animal to reverse full mu agonist

11
Q

Naloxone

A

Full opioid ANTagonist

12
Q

Naltrexone and Diprenophine

A

used to reverse carfentanil and etorphine

13
Q

Hydrocodone

A

opioid used as an antitussive

DEA Schedule II drug