Opiods Flashcards Preview

Class: Neuro > Opiods > Flashcards

Flashcards in Opiods Deck (10):
1

Name the 1 partial agonist opioid

BUPRENORPHINE

2

Name the 2 pure opioid antagonists

NALOXONE
NALTREXONE

3

Name the 3 mixed agonist-antagonists.

PENTAZOCINE
NALBUPHINE
BUTORPHANOL

4

Name the 3 main types of ENDOGENOUS opioids

ENDORPHINS (MORPHINE)
ENKEPHALINS
DYNORPHINS

5

Name the 2 actions of endogenous opioid peptides.

ACTION 1: Modulate pain transmission in the spinal cord
ACTION 2: Alter Ach release in the GI myenteric plexus

6

What is the precursor of beta endorphins? Which hormone does this precursor also release as a result of cleavage event?

POMC: Cleavage results in MELATONIN + ACTH - which then releases cortisol

7

Name the 2 full agonist opioids

FENTANYL
MORPHINE

8

ANKI: Opiod Analgesics inhibit the release of which 5 substances?

1) Ach
2) Serotonin
3) NE
4) Glu
5) Substance P

9

ANKI: Which 2 opioid toxicities do NOT develop tolerance?

MIOSIS
CONSTIPATION

10

ANKI: What are the 2 causes of opioid-induced GI pain?

1. CONSTIPATION from decreased motility
2. BILIARY COLIC from smooth muscle spasm of sphincter of Odi