Opiods Flashcards Preview

Class: Neuro > Opiods > Flashcards

Flashcards in Opiods Deck (10)
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1
Q

Name the 1 partial agonist opioid

A

BUPRENORPHINE

2
Q

Name the 2 pure opioid antagonists

A

NALOXONE

NALTREXONE

3
Q

Name the 3 mixed agonist-antagonists.

A

PENTAZOCINE
NALBUPHINE
BUTORPHANOL

4
Q

Name the 3 main types of ENDOGENOUS opioids

A

ENDORPHINS (MORPHINE)
ENKEPHALINS
DYNORPHINS

5
Q

Name the 2 actions of endogenous opioid peptides.

A

ACTION 1: Modulate pain transmission in the spinal cord

ACTION 2: Alter Ach release in the GI myenteric plexus

6
Q

What is the precursor of beta endorphins? Which hormone does this precursor also release as a result of cleavage event?

A

POMC: Cleavage results in MELATONIN + ACTH - which then releases cortisol

7
Q

Name the 2 full agonist opioids

A

FENTANYL

MORPHINE

8
Q

ANKI: Opiod Analgesics inhibit the release of which 5 substances?

A

1) Ach
2) Serotonin
3) NE
4) Glu
5) Substance P

9
Q

ANKI: Which 2 opioid toxicities do NOT develop tolerance?

A

MIOSIS

CONSTIPATION

10
Q

ANKI: What are the 2 causes of opioid-induced GI pain?

A
  1. CONSTIPATION from decreased motility

2. BILIARY COLIC from smooth muscle spasm of sphincter of Odi