Opiods- Part 1

Question 1

Opioids are

Answer 1

depressants with Analgesic properties

Question 2

examples of opioids

Answer 2

morphine

heroin

fentanyl

codeine

endorphin

Question 3

Sertuner

Answer 3

the first to successfully isolate and extract morphine crystals from the poppy seed juice

Question 4

the naturally occurring opiate codeine is identical in structure to

Answer 4

morphine except for the substitution of a methoxy for the hydroxyl group

Question 5

after oral administration, approximately 40 to 50 percent of the morphine reaches the

within 30 minutes for the

and 90 minutes of any

Answer 5

central nervous system

immediate release

extended released form

Question 6

heroin was first synthesized in

Answer 6

1874 and twice as potent as morphine

Question 7

Harrison Act-1914

Answer 7

regulated the production, importation, and distribution of opioids and coca-derived products

Question 8

phase one of opioid metabolism is carried out by

phase two is carried out by

Answer 8

CYP450

enzyme UGT2B7

Question 9

morphine is metabolized by

Answer 9

demethylation and glucuronidation

Question 10

4 opioid receptors

Answer 10

mu (after morphine)
delta (after vas deferens)
kappa( after the first ligand)
nociceptin