Opioides

Question 1

What is the main mechanism of action of opioids?

Answer 1

Opioids act primarily by binding to specific receptors in the central nervous system.

Question 2

True or False: Opioids are commonly used to treat severe pain.

Answer 2

True

Question 3

What are the three main classes of opioid receptors?

Answer 3

Mu, Delta, and Kappa receptors.

Question 4

Fill in the blank: Opioids are often classified based on their affinity for ______ receptors.

Answer 4

Mu

Question 5

What is the most common side effect of opioids?

Answer 5

Constipation

Question 6

True or False: Opioids are known to cause respiratory depression.

Answer 6

True

Question 7

What is the main metabolite of morphine?

Answer 7

Morphine-6-glucuronide

Question 8

What is the primary route of elimination for most opioids?

Answer 8

Renal excretion

Question 9

Fill in the blank: Opioid overdose can be reversed with the administration of ______.

Answer 9

Naloxone

Question 10

What is the most commonly used strong opioid in clinical practice?

Answer 10

Morphine

Question 11

True or False: Opioids have no potential for abuse or addiction.

Answer 11

False

Question 12

What is the main indication for the use of fentanyl?

Answer 12

Management of severe pain

Question 13

Fill in the blank: Opioids are often used as part of multimodal analgesia to reduce the risk of ______.

Answer 13

Opioid-related side effects

Question 14

What is the main adverse effect of long-term opioid use?

Answer 14

Physical dependence

Question 15

True or False: Opioids are contraindicated in patients with a history of substance abuse.

Answer 15

True

Question 16

What is the main difference between partial agonists and full agonists in terms of opioid receptors?

Answer 16

Partial agonists have a lower intrinsic activity compared to full agonists.

Question 17

Fill in the blank: Opioids are commonly used in the treatment of acute and chronic ______.

Answer 17

Pain

Question 18

What is the main effect of opioids on the central nervous system?

Answer 18

Analgesia

Question 19

True or False: Opioids can cause sedation and drowsiness.

Answer 19

True

Question 20

What is the main concern when using opioids in elderly patients?

Answer 20

Increased risk of falls and cognitive impairment

Question 21

Fill in the blank: Opioid withdrawal symptoms can include ______, nausea, and sweating.

Answer 21

Anxiety

Question 22

What is the main advantage of transdermal fentanyl over other opioids?

Answer 22

Extended duration of action

Question 23

True or False: Opioids are only available in oral formulations.

Answer 23

False

Question 24

What is the main consideration when converting between different opioids?

Answer 24

Equianalgesic dosing