Opthamology Flashcards

(52 cards)

1
Q

What is glaucoma?

A

Glaucoma is optic nerve damage due to rise in intraocular pressure due to block of aqueous

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2
Q

What is the normal intra-ocular pressure?

A

Normal IOP is 10-21mmHg

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3
Q

What happens in acute angle-closure glaucoma?

A

Iris bulges forward and seals off trabecular meshwork

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4
Q

What happens in chronic open-angle glaucoma?

A

There is increased resistance of trabecular meshwork

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5
Q

What is the Px of acute angle closure glaucoma?

A

Acute painful red eye

  • Blurred vision
  • Headaches, N&V
  • Seeing halos around lights
    o Hazy oedematous cornea
  • Evening symptoms
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6
Q

What is the Px and Ix of chronic open-angle glaucoma?

A

Is often asymptomatic

Ix:
- Visual field defects
Peripheral vision closes until tunnel vision

  • Fundoscopy -> Cupped optic disc
    Optic cup > 0.5 x optic disc
  • Measure IOP (> 24mmHg)
    o Non-contact tonometry = puff of air at cornea
    o Goldmann applanation tonometry
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7
Q

Mx of acute angle-closure glaucoma?

A

->Refer to ophthalmologist

Emergency mx:
- Patient lie flat with head not supported to relieve pressure
- Pilocarpine eye drops
o 2% in blue eyes
o 4% in brown eyes
- Acetazolamide 500mg orally
- Analgesia + anti-emetic

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8
Q

Mx of chronic open-angle glaucoma?

A

If >24 mmHg:
- Laser trabeculoplasty (SLT)

  • Not suitable for SLT ->
    1. Prostaglandin analogue
    2. B-blocker
    3. Carbonic anhydrase inhibitor
  • Advanced COAG -> glaucoma surgery + mitomycin-C (MMC)
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9
Q

What is blepharitis?

A

Inflamed eyelids

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10
Q

What are the different types of blepharitis?

A

Anterior - staphylococcal or seborrheic

Posterior - meibomian

Can also be mixed

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11
Q

Mx of blepharitis?

A

Mx – no cure, chronic intermittent condition:
1. Self-care (eyelid hygiene and warm press), no eye make-up

  1. Eyelid measures are ineffective:
    o Anterior blepharitis -> Topical antibiotic – Chloramphenicol
    o Posterior blepharitis + meibomian gland dysfunction & rosacea -> oral antibiotics
  2. Refer to ophthalmology if severe
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12
Q

What is a chalazion?

A

Meibomian gland blockage -> non-tender eyelid swelling

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13
Q

What is an entropion and mx?

A

Eyelids turn inwards with the lashes against the eyeball
-> corneal damage + ulceration

Mx:
Tape eyelid down + lubricating drops

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14
Q

What is an ectropion?

A

Eyelid turns outwards with inner aspect of eyelid exposed
-> exposure keratopathy

Mx:
Lubricating drops

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15
Q

What is trichiasis and mx?

A

Inward growth of eyelashes -> corneal damage + ulceration

Mx - Epilation, laser mx

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16
Q

Who gets cataracts?

A

Rx – elderly, smoking, alcohol, diabetes, steroids, hypocalcaemia
- Can also occur in children (congenital)

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17
Q

Px of cataracts?

A
  • Reduced acuity, progressive blurring, change of colour vision
  • Loss of red reflex
  • ‘Halos’ around lights
  • Gradual visual loss
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18
Q

Px of central retinal artery and vein occlusion?

A

Both - Sudden, painless unilateral loss of vision, RAPD

Amaurosis fugax – branch retinal artery occlusion
o “Black curtains coming down” – lasts a few minutes

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19
Q

What would be seen on fundoscopy of central retinal artery occlusion and central retinal vein occlusion?

A

Artery occlusion (light) - pale retina (due to lack of blood flow & oedema) with a cherry-red spot

Vein occlusion (dark) - Flame and blot haemorrhages, optic disc oedema, macular oedema

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20
Q

Mx of central retinal artery occlusion?

A

Refer to ophthalmology - immediate mx:
o Ocular massage
o Increase blood oxygen content and dilate renal arteries -> Sublingual isosorbide dinitrate and inhaled carbogen
o Reduce ocular pressure ->IV acetazolamide and mannitol

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21
Q

Mx of central retinal vein occlusion?

A

Mx – treat macular oedema + prevent neovascularisation
- Laser photocoagulation
- Intravitreal steroids
- Anti-VEGF

22
Q

Difference in px between peri-orbital and orbital cellulitis?

A

Painful eye movements, blurred vision and altered colour vision in orbital cellulitis

Peri-orbital cellulitis - Eyelid and skin infection in front of the orbital septum
Orbital cellulitis - Infection around the eyeball that involves tissues behind the orbital septum

23
Q

Chlamydia and gonorrhoea conjunctivitis px:

A

Chlamydia conjunctivitis:
- Chronic low-grade irritation and mucous discharge, often unilateral
- Follicles “grains of rice” on lower eyelid

Gonorrhoea conjunctivitis:
- Rapid with copious discharge, eyelid swelling & tender lymphadenopathy

24
Q

Rx of different conjunctivitis?

A

Bacterial -> Keratitis

Viral -> Keratoconjunctivitis

Gonorrhoea -> Corneal ulceration

25
Mx of bacterial conjunctivitis?
Self-limiting If severe -> chloramphenicol drops or fusidic acid
26
Mx of contact lens conjunctivitis?
Contact lens conjunctivitis -> stop contacts + antibiotics against gm -ve (gentamicin or levofloxacin)
27
Px of allergic conjunctivitis?
Bilateral ocular itching +/- watery discharge, conjunctival redness & swelling - Hx of rhinitis, asthma urticaria, eczema
28
Mx of allergic conjunctivitis?
Mx: 1. Avoidance of allergens, eye care 2. Topical antihistamine or mast cell stabiliser / topical antihistamine 3. Adjuvant – Topical ocular diclofenac
29
What is uveitis?
Inflammation of the uveal tract (iris, ciliary body and choroid)
30
Uveitis px:
Red painful eye, blurred vision, eye watering, photophobia - Deep aching pain - 20-50 years - Can be acute or chronic - Hypopyon – exudate in front of iris
31
Types of uveitis?
Anterior uveitis – anterior segment of eye (iris & ciliary body) inflammation (90% of cases) Intermediate uveitis – vitreous inflammation Posterior uveitis – retina and choroid inflammation Panuveitis – inflammation in the anterior chamber, vitreous and retina or choroid
32
Causes of uveitis?
Autoimmune (HLA-B27) [ankylosing spondylitis] Infective – herpes simplex, hzv, cytomegalovirus, toxoplasmosis Traumatic, neoplasia (rare)
33
Non-infectious uveitis mx:
Corticosteroids to reduce inflammation Mydriatic to paralyse ciliary body (cyclopentolate or atropine)
34
Difference in px between episcleritis and scleritis?
Episcleritis - normal vision, 50% are bilateral Scleritis - reduced visual acuity + severe pain
35
Mx of episcleritis?
Lubricant + NSAIDs
36
Mx of scleritis?
Emergency as life threatening Oral NSAIDs + steroids
37
Ix for keratitis?
Fluorescein Viral -> dendritic corneal ulcer Bacterial - > corneal ulcer + hypopyon
38
Mx for keratitis?
Viral -> refer to ophthalmology, acyclovir Bacterial -> topical antibiotics (oxaflocin)
39
Px of keratitis?
Inflammation of the cornea Px - Painful red eye, photophobia, vesicles around eye, foreign body sensation, watery eye, acute visual loss
40
Px of optic neuritis?
- Partial or total unilateral visual loss over a few days - Pain behind eye, worse on movement - Poor colour discrimination - Pale and swollen optic disc on fundoscopy - RAPD, central scotoma
41
Mx of optic neuritis?
High dose oral steroids (IV methylprednisolone)
42
Px of age-related macular degeneration?
- Gradual worsening central visual field loss (scotoma) - Reduced visual acuity - Distortion of vision where straight lines appear wavy (metamorphopsia)
43
Fundoscopy of age-related macular degeneration?
Drusen - Yellow deposits under the retina made of lipids
44
Types of age-related macular degeneration?
- Dry (90% – gradual) – drusen + macular atrophy - Wet (10% – subacute) – new vessels growing -> leakage of fluid and blood -> oedema
45
Mx of wet age-related macular degeneration?
Intra-vitreal anti-VEGF (ranibizumab)
46
Fundoscopy of diabetic retinopathy?
- Microaneurysms -> Blot haemorrhages - Exudate (cotton wool spots) - New blood vessel growth - Oedema
47
How is diabetic retinopathy classed?
Is it proliferative? (is there new vessel growth?) Is there maculopathy? (is the macula thickened?)
48
Complications of diabetic retinopathy?
- Retinal detachment - Vitreous haemorrhage - Optic neuropathy - Glaucoma - Cataracts
49
Px of retinal detachment?
Sudden onset, painless progressive visual field loss, floaters, recurrent flashes, and progressive visual loss
50
Mx of diabetic retinopathy?
Laser photocoagulation Anti-VEGF (ranibizumab) Vitreoretinal surgery
51
Keith Wagner classification of hypertensive retinopathy?
Stage: I Arteriolar narrowing II Arteriovenous nipping III Retinal haemorrhages, exudates, cotton wool spots IV Papilloedema
52
Visual field loss types:
Optic nerve defect – Monocular vision loss Optic chiasm defect – bitemporal hemianopia Optic tract defect or occipital cortex (macula spared) – Homonymous hemianopia