Option D5 Flashcards

1
Q

What is the endocrine system made out of ?

A

Comprised of ductless glands that release chemicals into the blood to regulate body functions

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2
Q

Endocrine System

What is a hormone?

A

A chemical messanger that is transported indiscrimanately to the bloodstream

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3
Q

Endocrine System

What is sepcial about hormones?

A

They are specific so only target cell or tissue that have appropriate target receptor

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4
Q

Endocrine Glands

What are examples of endocrine glands?

A

-Pancreas that releases insulin/glucagon to the liver to regulate blood sugar levels
-Adrenal gland release adrenaline and cortisol to many target organs for fight or flight anti-stress
-Thyroid gland releases thyroxin to the liver to regulate metabolic rate
-Pineal gland release melatonin to many organs and acts as digital clock

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5
Q

Endocrine Glands

What are neuroendocrine glands?

A

They link nervous to endocrine system

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6
Q

Endocrine Glands

What are examples of neuroendocrine glands?

A

Hypothalamus and pituatury gland

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7
Q

Types of Hormones

What are the 2 different types of hormones?

A

Steroid and peptide hormones

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8
Q

Steroid Hormones

What are steroid hormones?

A

They are lipophilic, meaning they can easily diffuse across membrane

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9
Q

Steroid Hormones

How is the receptor hormone complex formed?

A

The steroid hormones bind to receptors in nucleus or cytoplasm

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10
Q

Steroid Hormone

What happens to the receptor hormone complex?

A

Move into nucleus and bind to DNA acting as transcription factor for gene expression

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11
Q

**Steroid Hormones **

What are examples of steroid hormones?

A

Estrogen, progesterone, and testosterone

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12
Q

Peptide Hormones

What are peptide hormones?

A

They are hydrophylic and lipophobic, meaning they cannot move across plasma membrane

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13
Q

Peptide Hormones

How is the hormone receptor complex formed?

A

Hormones bind to receptors on surface found on surface of cell, which are coupled to internally anchored proteins

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14
Q

Peptide Hormones

What does the hormone receptor protein do?

A

They activate second messangers which initiate cell activity

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15
Q

Peptide Hormones

What is the process of cell activity initiation called?

A

Signal transduction

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16
Q

Peptide Hormones

What is the use of second messangers?

A

Amplify initial message

17
Q

**Peptide Hormones **

What are examples of peptide hormones?

A

Insulin, glucagon, and leptin

18
Q

Pituitary Gland

What is the hypothalamus?

A

The section of the brain that links the nervous and endocrine systems in order to maintain homeostasis

19
Q

Pituitary Gland

What are the functions of the hypothalamus?

A

-It receives information from nerves throughout the body and other parts of the brain and initiates endocrine responses
-It secretes neurochemicals (called releasing factors) into a portal system which target the anterior lobe of the pituitary gland
-It also secretes hormones directly into the blood via neurosecretory cells that extend into the posterior pituitary lobe

20
Q

Pituitary Gland

What is the pituitary gland?

A

Lies adjacent to the hypothalamus and is in direct contact due to a portal blood system

21
Q

Pituitary Gland

What are the 2 lobes that the pituitary gland consists of?

A

Anterior and posterior lobe

22
Q

Pituitary Gland

What is the function of the anterior lobe?

A

As the hypothalamus produces releasing factors into portal vessels by neurosecretory cells, the releasing factors will cause endocrine cells in the anterior pitiatuiry to release specific hormones into blood stream

23
Q

Pituitary Gland

What is the function of the posterior lobe?

A

Releases hormones produced by the hypothalamus itself via neurosecretory cells, these neurosecretory cells extend into the posterior lobe from the hypothalamus and release hormones into the blood

24
Q

Pituitary Gland

What are the body processes that pituitary hormones control?

A

-Metabolism
-Adult development
-Reproduction
-Growth
-Equilibrium

25
Q

Growth Hormone

What is the growth hormone?

A

Anabolic peptide hormone that stimulates growth

26
Q

Growth Hormone

What are the functions of the growth hormone?

A

-It acts directly to reduce the formation of adipose cells
-It acts indirectly via insulin growth factor (IGF) – produced by the liver – to increase muscle mass and bone size

27
Q

Growth Hormone

Where are growth hormones usually used?

A

By some athletes as a performance enhancer

28
Q

Growth Hormone

How can the growth hormone be detected?

A

Traditional urine testing could not detect doping, which historically made bans difficult to enforce. Recent blood tests can now identify between natural and artificial variants of growth hormone

29
Q

Lactation

What is lactation?

A

The production and secretion of milk by maternal mammary glands

30
Q

Lactation

What is lactation controlled by?

A

Oxytocin and prolactin

31
Q

Lactation

What is prolactin?

A

It is responsible for the development of the mammary glands and the production of milk. It is secreted by the anterior pituitary in response to the release of PRH from hypothalamus. The effects of prolactin are inhibited by progesterone, which prevents milk production from occurring prior to birth

32
Q

Lactation

What is oxytocin?

A

It is responsible for the release of milk from the mammary glands. It is produced in the hypothalamus and secreted by neurosecretory cells that extend into the posterior pituitary. Oxytocin release is triggered by stimulation of sensory receptors in the breast tissue by the suckling infant. This creates a positive feedback loop that will result in continuous oxytocin secretion until the infant stops feeding