Oral Aphthous ulcers Flashcards

1
Q

whar are apthous ulcers

A

AKA Canker Sores, Aphthous Stomatitis or Recurrent Aphthous Stomatitis

  • recurrent, painful, inflammatory, non infectious, non vesicular, immunologically mediated mucosal disease
  • occurs on nonkeratinized oral mucosal surfaces (tongue, floor of mouth, soft pallet NOT onf hard pallet or lips
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2
Q

Epidemiolgoy of canker sores

A
  • most prevalent oral lesion
  • occurs in 25%of population, 50% recurrence within 3 motnhs
  • first ocurnece 10-20 years old: more common in childhood and early adulthood
  • freq and sevarity decrease ith age
  • populations with higher freq = women under 40, family history of AU, middle and upper middle socioeconomic groups
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3
Q

etiology of canker sores

A
  • local trauma (mucosal injury): biting cheek, braces
  • stress
  • systemic conditions
  • allergy/senstitiy
  • food
  • immunologic states
  • nutrional deficienies: Ca and Vit B
  • cessation or restating tobacco use
  • genetic predisposion
  • mediaction: NSAIDS

maybe hormonal changes

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4
Q

risk factors for AU

A
  • family history
  • female
  • less than 40

immunocompromised (HIV, transplant)

  • vitamin and mineral deficiencies
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5
Q

clinical presentation of canker sores

A
  • one or more shallow sores with a white or cream colours coating
  • erthematous “halo” of infalmed tissue around ucler

=painful

-history of recurrent episodes

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6
Q

what are thet ypes of canker sores

A
  1. Minor
    • 2-10 mm, oval shape
    • occurs singly or in clusers <5
    • 7-10 days
    • no scarring
  2. Major
    • >10mm, deeper and occurs in clusters of 2 or more
    • irregualr shape
    • may persit for weeks
    • scar potential
  3. Herpetiform
    • 2-3mm
    • occur in clusters of 10-100, irregualr shape
    • 7-30 days
    • scar potential
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7
Q

differential diagnosis of AU

(thigns it can be mistaken for

A
  • Behcet syndome: mouth sores 1st preseting symptom
  • IBS (Chrons): will have other GI symptoms
  • Lupus erthematosus
  • Leukoplaia: pre cancerous, common in smokers
  • viral ifnections: herpes, varicella sozter, mono, will also present w/ fever
  • Treponemal infections (syphilis)
  • fungal infections (thrush): will get a white coating
  • hematologic disease (cyclic neutropeia)
  • neoplasms (squamous cell carcinoma): not inside mouth
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8
Q
A
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9
Q

classes of drugs that can cause drug induced oral ulcers

A
  • NSAIDs, cadiology, immunosepressant, anticancer agents, psychiatry agents

* if on PPI or iron def meds, prob have a nutritional deficiency that may cause it

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10
Q

what are med falgs for major or herpetiform apthae

A
  • Ulcer diameter >10 mm
  • Ulcer duration >14 days
  • >5 ulcers present
  • multiple clusters of ulcers that may have coalesced
  • difficulty chewing or swallowing due to pain
  • History of having ulcers that last >14 days, heal with scarring and recur 6-12 times/year
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11
Q

what are red falcts for AU that could indicate ulcers are from a secondary condition

A
  • first AU was after age 30
  • systemic illness symptoms (fever_
  • immunocomprised due to meds or disease state
  • lesions present elsewhere on body
  • severe pain
  • radiation theapy

recurrences > 6x per year(underlying cause triggering it

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12
Q

who are self care candidates for AU

A
  • 1-5 round or oval mouth ulcers that are :

Painful

Located on nonkeratinized mucosal surfaces of movable mouth parts

Flat or crater-like with an erythematous “halo” margin

White/yellow/grey centre

Each lesion ≤ 10mm in diameter

*also if have personal history of childhoos ulcers, family histroy of recurrent or recently stopped smoking

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13
Q

goals of therapy for AU

A
  1. relive local pain and dsicomfort
  2. restore functiona nd oral hygeine practices (speaking swallowing)
  3. ensure adequate nutritoinal intake
  4. reudce duration of ulceres
  5. decrease frequency and severity of recurrences (cant be cured)
  6. prevent complication
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14
Q

prevention measures for AU

A
  • avoid local traume (self biting, shapred edge foods, replace tooth brush heads early)
  • avoid allergens
  • avoid dehydration

0 avoid nutritoinal deficiencies

  • minimize emotional distress
  • manage drug induced causes
  • maange underlying systemic disease causes
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15
Q

non pharmacologic treatment for AU

A

Repair or remove oral trauma-causing agent

Avoid food & drinks that cause pain

Avoid using harsh toothpastes and mouthwashes with SLS

Maintain regular daily oral hygiene

Ice application

Cleanse the lesion(s)

• Rinse the mouth with salt water (2.5-5 mL table salt per 250 mL warm water) several times a day, especially after meals

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16
Q

cleansing rinses for AU

A
  • NO EVIDENCE TO SUGGEST OTHER CLEANSING RINSES PROVODE ADVANTAGE OVER SALINE RINSES FOR APHTHOUS ULCERS

*all you need is salt water

17
Q

first lien therapy for AU

A
  • anesthetics (local)
  • anti-inflammatories
  • mucosal protectants
18
Q

first line of treatment for AU

A

*non prescription options

  • Mucosal protectants
    • hydroypropyl cellulose, carboxymethyl cellulose
    • forms protective layer over lesions = temportary pain relief
    • apply as needed, often TID-QID
  • Local oral anesthetics
    • benzocaine (Orajel, Anbesol), lidocaine (xylocaine viscous)
    • short duration of action, may be used with protectants
    • AAA QID for <1 week ; apply ice before using gel formulation
    • avoid eating, drinking and speakign 30 min post application
  • Local oral anesthetic + mucosal protectnat
    • orabase with benzocaine
  • Oral analgesics
    • acetaminophen: AVOID NSAIDS
19
Q

second line pharmacologic treatments for AU

A
  • Supplementaition
    • B1, B2, B6, B12, Iron, Folic acid, zinc
  • Milk of Magnesia & Diphenhydramine allergy liquid
20
Q

warnings and contraindications for AU

A
  • Avoid counterirritants
  • Avoid placing ASA directly on lesion
  • Avoid dentifrices containing SLS
  • Avoid caines in patients with a hypersensitivity
  • do not swallow oral debriding and wound cleansing agents
21
Q

Monitoring & follow up

A
  • Assess benefit
    • reudce pain and significant healing of ulcer
      • patient; daily
      • RPh: q3-7 days x 1 week than 1 week later
        • if ulcer is still present or warners after 12 days of self care could be chronic-> refer
  • Asses adverse effect treatment
    • ex ecessive local irritation or other complications
      • patient to access daily
      • Rph Q3days f1w than 1 week alter