Oral Board MDSO

Question 1

Acetaminophen MDSOs

Answer 1

Adult - Analgesia
Adult - Fever
Pediatric - Fever

Question 2

Acetaminophen - Classification

Answer 2

Antipyretic, Analgesic

Question 3

Acetaminophen Details

Answer 3

Onset - 30-60 minutes
Peak - n/a
T1/2 - n/a
Duration - 4-6 hours

Question 4

Acetaminophen MOA

Answer 4

Effects are believed to be related to the inhibition of prostaglandin synthetase, with antipyretic effects produced through the action on the hypothalamic heat-regulating centre.

Question 5

Acetylcystine MDSO

Answer 5

Tylenol OD/Tox

Question 6

Acetylcystine - Classification

Answer 6

Mucolytic

Question 7

Acetylcystine - Details

Answer 7

Onset - immediate
Peak - n/a
T1/2 - n/a
Duration - n/a

Question 8

Acetylcystine MOA

Answer 8

Moderates nerve and muscle performance via action potential excitation threshold regulation.

Question 9

Acetylcystine Complications & Adverse Effects

Answer 9

Anaphylactoid reactions. Likely due to dose-related stimulation of histamine release rather than a true allergic response. If this occurs, restart infusion at a slower rate.

Question 10

Acetaminophen Complications & Adverse Effects

Answer 10

Skin: Rash, urticaria
Hepatic: Mild increase in hepatic enzymes mat occur and is reversible when the drug is withdrawn
GI: N/V, bloating.

Question 11

ASA MDSO

Answer 11

NSTEMI
ACS

Question 12

ASA Classification

Answer 12

NSAID, Analgesia, Antipyretic, Anticoagulant

Question 13

ASA Details

Answer 13

Onset - 5 minutes
Peak - 1-2 hours
T1/2 - 3-10 hours (dose dependent)
Duration - 6 hours

Question 14

ASA MOA

Answer 14

Inhibits COX 1 & 2 enzymes which results in decreased formation of prostaglandin precursors. Inhibits formation of prostaglandin derivative thromboxane A2, via acetylation of platelet cyclooxyrgenase, thus inhibiting platelet aggregation.

Question 15

ASA Complications and Adverse Effects

Answer 15

Hemorrhage
HI ulcer, epigastric distress, gastritis, GI erosion, heartburn, nausea, stomach pain, vomiting.
Increased blood urea nitrogen, increased serum creatinine, interstitial nephritis, renal failure
Skin rash, urticaria

Question 16

ASA Contraindications

Answer 16

Previous stroke in the last 24 hours.

Question 17

Adenosine MDSO

Answer 17

PSVT

Question 18

Adenosine Classification

Answer 18

Antiarrhythmic (Class V)

Question 19

Adenosine Details

Answer 19

Onset - Less than 60 seconds
Peak - 60 seconds
T1/2 - 10 seconds
Duration - 1-2 minutes

Question 20

Adenosine MOA

Answer 20

Slows conduction through AV node, interrupts AVNRT and can restore NSR in PSVT via modulation of the K+ currents and the blunging of catecholamine response.

Question 21

Adenosine Complications & Adverse Effects

Answer 21

Non-cardiac: Facial flushing, chest pain, dyspnea, headache, light-headedness.
Cardiac: 1st, 2nd, 3rd degree heart block, systole, and varied arrhythmias.

Question 22

Adenosine Contraindications

Answer 22

2nd/3rd degree block
Sick sinus syndrome
Symptomatic bradycardia
Known or suspected bronchoconstrictive or bronchospastic lung disease, asthma.

Question 23

Amiodarone MDSO

Answer 23

Adult - Nom-traumatic cardiac arrest
Adult - VTach with perfusion
Adult - Cardiogenic Shock
Pediatric - Non-traumatic cardiac arrest

Question 24

Amiodarone Classification

Answer 24

Antiarrhythmic (Class III)

Question 25

Amiodarone Details

Answer 25

Onset - 5-30 miuntes Peak - 1-2 hours T1/2 - 4-12 hours Duration - 10-12 hours

Question 26

Amiodarone MOA

Answer 26

Prolongs the action potential and refractory period in myocardial tissue, blocks potassium channels.

Question 27

Amiodarone Complications & Adverse Effects

Answer 27

Hypotension, bradycardia, heart block, respiratory failure, heart failure. Pain, phlebitis at injection site Hyper/hypothyroid, pulmonary injury, cutaneous reaction, hepatotoxicity

Question 28

Amiodarone Contraindications

Answer 28

Severe SA node disease resulting in pre-existing bradycardia Heart block, bradycardia with associated syncope except in patients with a functioning pacemaker Prolonged QR particularly if hypomagnesemic.

Question 29

Ampicillin MDSO

Answer 29

Obstetrics Pre-Term Obstetrical Complications

Question 30

Ampicillin Classification

Answer 30

Antibiotic

Question 31

Ampicillin Details

Answer 31

Onset - 30-60 minutes Peak - 1-3 hours T1/2 - 1-2 hours Duration - 3-4 hours

Question 32

Ampicillin MOA

Answer 32

Binds to one or more of the penicillin-binding proteins.

Question 33

Ampicillin Complications & Adverse Effects

Answer 33

Anaphylaxis CNS: Seizures if given too rapid Hematologic: anemia, leukopenia and thrombocytopenia.