ORAL DIAGNOSIS Pathology and Diagnosis pt 2 Flashcards
(191 cards)
___ is a group of neoplasms of bone marrow. what are the precursors?
- leukemias
- lymphocyte or myeloid precursors
in leukemias, malignant cells occupy and replace normal marrow cells, including ___. the malignant cells are also released into the ___
- megakaryocytes (platelet forming cells)
- peripheral blood
what are the causes of leukemias?
- genetic factors, such as chromosome translocations
- environmental agents (benzene, radiation)
- viruses (human T-lymphotropic virus 1)
classification of leukemia is based on ___ and ___
cell lineage and whether the disease is acute or chronic
what are the clinical features of leukemia?
- bleeding (owing to reduced platelets), fatigue (owing to anemia), and infection (owing to agranulocytosis) are important clinical signs of leukemias
- infiltration of gingival tissues by leukemic cells is common in chronic monocytic leukemia; gingiva is red, boggy, and hemorrhagic
what is the treatment for leukemias?
chemotherapy is quite successful for acute leukemias, but is less so for chronic leukemias
odontogenic cysts are derived from cells that are associated with ___
tooth formation
in odontogenic cysts, the stimulus for cystic change is unknown in all cysts except for ___ and ___
periapical cysts and some odontogenic keratocysts (keratocystic odontogenic tumors)
what is the most common odontogenic cyst? what is it always associated with?
- periapical (radicular) cyst
- always associated with a nonvital tooth
how do periapical cysts form?
- necrotic pulp causes periapical inflammation (can be acute or chronic)
- rests of malassez within a dental granuloma epithelialize the lesion, resulting in the formation of a cyst
describe the difference in acute and chronic periapical cysts
- if acute, a periapical abscess forms after periapical inflammation
- if chronic, a dental granuloma (granulation tissue and chronic inflammatory cells) forms after periapical inflammation
how is a periapical cyst treated?
RCT, apicoectomy, or tooth extraction with apical curettage
how does a dentigerous cyst manifest radiographically?
a radiolucency around the crown of an impacted tooth
which teeth are most commonly affected by dentigerous cysts?
third molars and canines
an eruption cyst is a ___ cyst that occurs over a tooth that has erupted into the submucosa
dentigerous cyst
in dentigerous cysts, the epithelial lining from reduced enamel epithelium has the potential to transform into ___
ameloblastoma
a ___ is a unilocular or multilocular lucency in the lateral periodontal membrane of adults
lateral periodontal cyst
where are most lateral periodontal cysts located?
most are found in the mandibular premolar region and are associated with a vital tooth
___ is the soft tissue counterpart of a lateral periodontal cyst
gingival cyst of the adult
gingival cysts of a newborn present as ___ resulting from ___
multiple small gingival nodules resulting from cystification of rests of the dental lamina
gingival cysts of the newborn are also called ___. what are inclusion cysts in the palates of infants called?
- bohn’s nodules
- epstein’s pearls
what is the treatment for gingival cysts of the newborn?
none
odontogenic keratocysts (keratocystic odontogenic tumors) are lesions that may be clinically aggressive, recurrent, or associated with which syndrome?
nevoid basal cell carcinoma (gorlin) syndrome
what characterizes nevoid basal cell carcinoma (gorlin) syndrome?
- multiple odontogenic keratocysts
- numerous cutaneous basal cell carcinomas
- skeletal abnormalities
- calcified falx
- other stigmata