Oral Path Exam 2 - Papillary Growths

Question 1

What lesion?

Double-stranded DNA virus

Answer 1

HPV

Question 2

What lesion?

Infects epithelial cells (cutaneous and mucous membranes)

Answer 2

HPV

Question 3

What lesion?

> 200 types in humans

Answer 3

HPV

Question 4

What lesion?

Associated with benign, potentially malignant, and malignant epithelial lesions

Answer 4

HPV

Question 5

How many types of HPV infect the oral mucosa?

Answer 5

> 30 types

Question 6

What HPV type is associated with oral squamous papilloma?

Answer 6

6, 11

Question 7

What HPV type is associated with oropharyngeal squamous cell carcinoma?

Answer 7

16

Question 8

What HPV type is associated with verruca vulgaris?

Answer 8

2

Question 9

What HPV type is associated with condyloma acuminatum?

Answer 9

6, 11

Question 10

When did the HPV vaccine become routine?

Answer 10

2006

Question 11

What is the current HPV vaccine?

Answer 11

9-valent (Gardasil 9)

Question 12

The HPV vaccine is recommended for all adolescents ages _________

Answer 12

11-12

Question 13

What is the HPV vaccine indicated for prevention of?

Answer 13

Genital warts
Precancers/cancers of cervix, vulva, vagina, anus
Oropharyngeal and other HN cancers

Question 14

What lesion?

Caused by benign proliferation of stratified squamous epithelium

Answer 14

Squamous papilloma

Question 15

What lesion?

Diagnosed most often btwn 30-50 yrs old

Answer 15

Squamous papilloma

Question 16

What lesion?

White or pink exophytic nodule w/ fingerlike surface projections

Answer 16

Squamous papilloma

Question 17

What lesion?

Often pedunculated

Answer 17

Squamous papilloma

Question 18

What lesion?

Commonly found on soft palate, tongue, and lips

Answer 18

Squamous papilloma

Question 19

What lesion?

Can be difficult to differentiate from verruca vulgaris, condyloma acuminatum, and others clinically

Answer 19

Squamous papilloma

Question 20

What lesions?

Diagnosed by biopsy

Answer 20

Squamous papilloma
Condyloma acuminatum

Question 21

What lesion?

Tx = excisional biopsy

Answer 21

Squamous papilloma

Question 22

What lesion?

Caused by benign hyperplasia of stratified squamous epithelium

Answer 22

Verruca vulgaris (“common wart”)

Question 23

What lesions?

Contagious

Answer 23

Verruca vulgaris (“common wart”)
Condyloma acuminatum

Question 24

What lesion?

Most common in kids

Answer 24

Verruca vulgaris (“common wart”)

Question 25

What lesion? Painless papule w/ papillary projections or rough, pebbly surface

Answer 25

Verruca vulgaris ("common wart")

Question 26

What lesion? Can have multiple or clustered lesions

Answer 26

Verruca vulgaris ("common wart")

Question 27

What lesion? Skin of hands is most common

Answer 27

Verruca vulgaris ("common wart")

Question 28

What lesion? Most common oral sites are vermilion border, labial mucosa, and anterior tongue

Answer 28

Verruca vulgaris ("common wart")

Question 29

What lesion? Diagnosed clinically and biopsy

Answer 29

Verruca vulgaris ("common wart")

Question 30

What lesion? Can resolve spontaneously (2/3rds resolve within 2 yrs)

Answer 30

Verruca vulgaris ("common wart")

Question 31

What lesion? Tx = topical salicylic acid, cryotherapy, surgical excision

Answer 31

Verruca vulgaris ("common wart")

Question 32

What is the first line tx for verruca vulgaris found in the mouth?

Answer 32

Surgical excision

Question 33

What lesion? Caused by proliferation of stratified squamous epithelium

Answer 33

Condyloma acuminatum

Question 34

What lesion? Common sexually transmitted disease

Answer 34

Condyloma acuminatum

Question 35

What lesion? Often found in teenagers and young adults

Answer 35

Condyloma acuminatum

Question 36

What lesion? Most commonly anogenital

Answer 36

Condyloma acuminatum

Question 37

What lesion? Oral lesions most frequently on labial mucosa and lingual frenum

Answer 37

Condyloma acuminatum

Question 38

What lesion? Sessile Pink Exophytic mass Short, blunted surface projections

Answer 38

Condyloma acuminatum

Question 39

What lesion? Larger than squamous papillomas

Answer 39

Condyloma acuminatum

Question 40

What lesion? May be single or clustered

Answer 40

Condyloma acuminatum

Question 41

What lesion? Tx = excisional biopsy, cryotherapy, or laser ablation

Answer 41

Condyloma acuminatum

Question 42

What lesion? Caused by ill-fitting denture, poor denture hygiene, wearing denture 24 hrs/day

Answer 42

Inflammatory papillary hyperplasia

Question 43

What lesion? Effects denture or retainer wearers

Answer 43

Inflammatory papillary hyperplasia

Question 44

What lesion? Can also occur in pts w/ high palatal vault and mouth breathers

Answer 44

Inflammatory papillary hyperplasia

Question 45

What lesion? Usually asymptomatic

Answer 45

Inflammatory papillary hyperplasia

Question 46

What lesion? Erythematous pebbly or papillary mucosa

Answer 46

Inflammatory papillary hyperplasia

Question 47

What lesion? Midportion of hard palate most frequently affected

Answer 47

Inflammatory papillary hyperplasia

Question 48

What lesion? Diagnosed clinically, but biopsy can be done if there is any doubt

Answer 48

Inflammatory papillary hyperplasia

Question 49

What lesion? Tx = improve denture hygiene/remake ill-fitting denture; antifungal if indicated

Answer 49

Inflammatory papillary hyperplasia

Question 50

What are 3 other important diagnoses that may appear papillary?

Answer 50

Proliferative verrucous leukoplakia (PVL) Squamous cell carcinoma Verrucous carcinoma

Question 51

T/F: PVL, SCC, and verrucous carcinoma are generally going to show more persistent, continuous growth and will grow bigger than most HPV lesions

Answer 51

True

Question 52

What is the gold standard for accurate diagnosis?

Answer 52

Biopsy