Oral Sedation and Anxiety Control Flashcards Preview

Pain Management > Oral Sedation and Anxiety Control > Flashcards

Flashcards in Oral Sedation and Anxiety Control Deck (39):
1

The dissociation constant has to match the pH of the compartment for the drug to be absorbed.

True

2

Some drugs need these to be broken down.

Bile salts or bacteria.

3

Why do anti-cholinergics delay gastric emptying?

Because the stomach is stimulated by the Vagus nerve, which is cholinergic.

4

These three things cause delayed gastric emptying.

Diabetes, Scleroderma, Amyloidosis

5

The fraction of the drug dose that gets into the systemic circulation.

Bioavailability

6

T/F: You cannot titrate oral sedatives.

True

7

First pass metabolism of a drug occurs in what organ?

Liver

8

Diffusion from high to low concentration.

Passive diffusion

9

These molecules diffuse more readily.

Small, non-polar lipid soluble molecules

10

What is ion-pair transport?

Anions bind to Cations to form a neutral complex that can pass the cell membrane by passive diffusion.

11

These:

-Reversibly associated with the drug
-Buffer wide fluctuations in free drug concentration

Plasma proteins

12

If the drug readily binds to these, they will stay in the body longer.

Plasma proteins

13

Obesity and drug distribution

Obese people with large lipid stores hold onto the drug longer.

14

Metabolism of a drug involves this.

Conversion from lipid to water soluble.

15

Where most agents get metabolized.

Liver

16

Phase I reactions in drug metabolism involve what?

Oxidation
Reduction
Hydrolysis

17

Phase II reactions in drug metabolism

Conjugation

18

The drug is combined with glucuronic acid to form water soluble complexes.

Conjugation

19

Most drugs are eliminated through which organ?

Kidneys

20

What is this? :

Drug is conjugated with biliary salts, goes through the intestinal tract, and gets recycled and reabsorbed.

Enterohepatic cycling

21

What kind of sedation is not recommended for kids under 12?

Moderate

22

Types of sedation

Mild
Moderate
Deep

23

May need to maintain the airway in this type of sedation.

Deep

24

Patients cannot be easily aroused during this type of sedation.

Deep

25

Stages of Anesthesia

Stage 1, 2, 3, 4

26

Stage 1 Anesthesia

Analgesia

27

Stage 2 Anesthesia

Delirium/Excitement

28

Stage 3 Anesthesia

Surgical Anesthesia

29

Stage 4 Anesthesia

Medullary Paralysis

30

Minimally depressed level of consciousness.

Cognition and Coordination are modestly impaired.

Ventilatory and cardiovascular functions are un-impaired.

Minimal sedation

31

This type of sedation:

patients respond to verbal commands alone or accompanied by light tactile stimulation.

Moderate sedation

32

Drug induced loss of consciousness in which patients are not arousable even by painful stimulation.

General Anesthesia

33

Requires a device to maintain a patent airway.

CV function may be impaired.

General anesthesia.

34

If lower BP more than this %, can cause brain damage bc not enough pressure to pump blood to the brain.

25

35

Oxygenated Hb absorbs _____ light at ____ nm.

Infrared; 990

36

You regain full psychological and physical capacity in this stage of recovery.

Late

37

You regain full psychomotor function and resume physical activity in this stage of recovery.

Intermediate

38

Used as discharge criteria.

Aldrete Scoring System

39

Characteristics looked at for the Aldrete System

Activity
Respiration
Circulation
Consciousnes
Color