Orthomyxovirus/Influenza Flashcards

(62 cards)

1
Q

Influenzaviruses have segmented genome

A

T

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2
Q

HPAI and LPAI strains differ in the number of basal amino acids in the HA protein

A

T

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3
Q

HA protein of influenza viruses is responsible for the attachment to the cell

A

T

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4
Q

The M2 protein of influenza viruses serves as an ion channel important in the decapsidation

A

T

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5
Q

Antigenic drift means serials of point mutations in the HA and NA genes

A

T

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6
Q

The NA protein in the influenza virus is responsible for the release from the infected cells

A

T

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7
Q

Enzymatic cleavage of the HA protein is needed for the influenza virus penetration into the cell

A

T

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8
Q

Genetic reassortment of human and animal influenza viruses result in the occurrence of new
human influenza strains

A

T

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9
Q

Bats have an important role in the epidemiology of influenza

A

F

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10
Q

Antigenic shift is behind the influenza pandemics

A

T

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11
Q

Influenza viruses are classified into genera by their HA and NA proteins

A

F

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12
Q

Influenza causes persistent infection in donkey

A

F

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13
Q

The serotype of influenza viruses is determined by their HA and NA proteins

A

T

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14
Q

The influenza viruses cause respiratory signs in sea mammals

A

T

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15
Q

The host range of influenza virus is determined by the NA protein

A

F?

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16
Q

The bird to human host switch of influenza virus is mediated by swine

A

T

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17
Q

The main host of influenza is the swine

A

F

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18
Q

In humans inactivated vaccines are used for the immunisation against influenza

A

T

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19
Q

Antigenic drift is behind the seasonal influenza epidemics

A

T

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20
Q

Antigenic shift means the reassortment of the influenzavirus genome segments

A

T

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21
Q

Influenzaviruses are sensitive to drying out

A

T

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22
Q

For the in vitro propagation of influenza viruses embryonated eggs is used

A

T

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23
Q

The high virulence of some influenza A viruses is the result of mutations in the HA gene

A

T

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24
Q

Influenza viruses are classified into genera by their HA and NA proteins

A

F

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25
Dogs are susceptible to horse origin influenza strains
T
26
The HPAI strains can cause CNS signs
T
27
HPAI causes blood vessel damages and generalised infections
T
28
The HPAI strains are usually developed from the H5 and H7 influenza viruses
T
29
The LPAI causes immunosuppression
T
30
Cat is susceptible to human seasonal influenza
F
31
HPAI strains are mutations of LPAI strains
T
32
HPAI strains belong into a certain haemagglutinin types
F
33
Influenzas Causes enteric symptoms in human.
T
34
Anti-neuraminidase drugs inhibit the decapsidation of influenza viruses
F
35
Swine recovered from influenza should not be kept for breeding
T
36
Influenza causes high morbidity but low mortality in swine
T
37
The HPAI causes skin haemorrhages in swine
F
38
Swine influenza outbreaks occur usually during summer
F
39
The mortality of swine influenza is high
F
40
Swine influenza causes high morbidity rate
T
41
To prevent complications of swine influenza penicillin injections are given to sick pigs
T
42
Swine influenza is easily transmitted to people
F?
43
To prevent complications of swine influenza, antibiotics used
T
44
In swine all influenza variants can be detected
F
45
In a horse influenza outbreak all infected horses must be killed
F
46
The generalized symptoms of horse influenza are result of the interferon response
T
47
Racehorses should be vaccinated before the influenza season
F
48
Breeding mares should be vaccinated before the influenza season
F
49
Influenza causes persistent infection in horses
F
50
The eggs produced in LPAI infected flock can be hatched
T
51
The HPAI infection can be unambiguously differentiated from Newcastle disease by the clinical signs
F
52
The HPAI strains can cause clinical signs in waterfowl
T
53
In poultry farms LPAI may be endemic without clinical signs
T
54
Waterfowl can carry the influenza viruses for long time
T
55
Influenza viruses are shed by birds exclusively in the nasal discharge
F
56
Avian influenza is zoonotic
T
57
The virulence of avian influenza is determined by the i.v. pathogeny index and mortality
T
58
Avian influenza can switch directly to human and cause epidemics with high case numbers as result of human to human transmission
F
59
In birds all influenza variants can be detected
T
60
Avian influenza of high economic impact is caused by HPAI strains
T
61
Avian influenza virus is primarily spread through bronchial discharge and aerogenic route
F
62
Avian influenza spread by bronchial discharge
T??