Orthopaedics and Traumatology Flashcards
(99 cards)
Osteoarthritis
• Most common type of Arthritis; Characterised by Cartilage loss with Periarticular Bone
Response; Multifactoral process with Mechanical factors
o Significant inflammation of Articular and Periarticular structures
o Most common cause of Disability in the Western world in older adults
• Increasing prevalence with age; Uncommon <50yrs; Most >60yrs have radiological evidence
but only 1/4 symptomatic; Geographical Variation (e.g. Hip OA more common in Eurasians,
Knee OA more common in Asians)
• Joint Pain, Morning Joint Stiffness, Functional Limitation, Crepitus, Restricted Movement,
Bony Enlargement, Joint Effusion and Inflammation, Bone Instability and Muscle Wasting
Pathophysiology of Osteoarthritis
• OA is a result of active, sometimes inflammatory, potentially reparative
processes rather than inevitable result of trauma and ageing
• Predisposing Factors – Obesity, Hereditary, Gender, Hypermobility, Trauma, Congenital Joint Dysplasia or Dislocations, Occupation, Sport
• Abnormal local mechanical factors that
affect loading and wear
• Inflammation starting at Periarticular Entheses in inflammatory phase; Focal Destruction of
Articular Cartilage commonly seen
o Spectrum between Atrophic disease (Cartilage destruction without Subchondral bone
response) to Hypertrophic disease (Massive new bone formation on joint margins)
o Focal Synovitis due to fragments of shed bone or cartilage
• Under normal circumstances, Cartilage degradation by wear and
production by Chondrocytes is balanced; In OA, balance is lost and focal erosion develops
o Disordered repair from adjacent cartilage, failure of ECM
synthesis and Fibrillation and Fissuring of joint surface
o Cartilage ulceration lead to exposure of bone to
increased stress, leading to Microfractures and Cysts;
Attempted repair leads to Abnormal Sclerotic
Subchondral bone formation and Osteophytes
Nodal OA
DIPs more often affected than PIPs; Often start
around female menopause; Can co-exist with Thumb-base OA
o Painful, associated with Tenderness, Swelling,
Inflammation and Impairment
o Inflammatory phase can settle over time, leaving painless
bony swellings posterolaterally (Heberden’s Nodes on
DIPs, Bouchard’s nodes on PIPs)
o XR: Marginal Osteophytes and Joint space loss
Hip OA
7-25% of Adult Caucasians; Less common in African and Asians
o Superior-pole Hip OA – Joint space narrowing and Sclerosis
affecting weight-bearing upper surface of Femoral Head and
Acetabulum; More common in men
▪ Early onset assoc Acetabular Dysplasia or Labral tears
o Medial Cartilage Loss – More common in women and associated
with hand involvement (=Nodal Generalised OA); Bilateral and
rapidly disabling
Knee OA
40% >75yrs; More common in women
o Strongly linked to Obesity; Typically, bilateral
o Medial compartment most commonly affected leading to Varus
deformity; Retropatellar OA may co-exist; Marrow involvement
predicts progression and eventual joint replacement
o RF: Previous Trauma, Meniscal and Crucial Ligamental tears
Crystal Associated OA
CPPD in Cartilage (= Chondrocalcinosis); Knees
and Wrist TFCC most commonly affected; Patchy, linear Calcification on XR
o Chronic Arthropathy (Pseudo-OA) especially in Elderly women with severe CPPD
o Marked Osteophyte and Cyst formation
o Associated with Pseudogout (Acute Crystal Arthritis)
o Presence of Calcium Apatite in Bloody Joint Effusion has poor outlook, joints require
early surgical replacement
Rarer Forms of OA
Primary Generalised OA (NGOA = Nodal OA typically with either Knees, first MTP, Hip or Intervertebral; Sudden and severe onset; Female with familial tendency) and Erosive OA (DIPs, PIPs equally affected; Poor functional outcomes, marked radiological Osteolysis; Destructive phases followed by remodelling
Management of Osteoarthritis: Investigations
Investigations – ESR might be normal, CRP mildly raised; RF
and ANA negative
o XR changes usually only when damage is advanced;
Useful for preop planning
o MR – Meniscal tears, Early Cartilage Injury and
Osteochondral changes
o Arthroscopy – Identify Early Fissuring and Surface
Erosion; Aspiration of Synovial Fluid during painful effusion shows viscous fluids with
few Leukocytes
Management of Osteoarthritis: Treatment
• Guiding principle to treat Symptoms and Disability ≠ Radiological appearance
o Education about disease reduces Pain, Distress and Disability, and improves
Compliance with treatment; Psychosocial factors to be considered
• Physical Therapy – Weight Loss, Strength and Stability-building Exercises, Hydrotherapy
o Local Heat and Ice packs, Massages, Local NSAID gels
o Insoles for flat feet, Contralateral walking sticks
• Analgesia and Anti-inflammatories – Paracetamol before NSAIDs; NSAIDs and COX-2 Inhibitors
used intermittently when possible; Cautious use of Opioids in elderly
• Intraarticular Corticosteroids – Short term improvement during Painful Effusions
o Frequent injections to same joint should be avoided
• No clinical benefit from Glucosamine and Chondroitin; Unclear benefit of Intraarticular
Hyaluronan; No proven DMARDs for OA
Surgical Management of Osteoarthritis
o Replacement Arthroplasty (E.g. THR, TKR); 1% Complication rate; Prosthesis Loosening and Late Infection most serious o Novel Arthroplasty Techniques – Hip Resurfacing, Unicompartmental Knee Replacement (less major) o Other Surgical techniques include Realignment Osteotomy, Excision MTP Arthroplasty, MTP Joint Fusion
Perthe’s Disease
Idiopathic (possibly Avascular)
Necrosis of Proximal Femoral Epiphysis
o Presents as a painless limp usually in boys 3
– 12yrs; Occasionally Bilateral
o If Severe, might require Surgical correction
Transient Synovitis of the Hip (Irritable Hip)
Painful
limitation of movement typically Unilateral; After
URTI usually in boys
o Usually resolves after few weeks; 2 – 3% develop Perthe’s disease
o Treatment with Rest and NSAIDs until pain resolves, typically 7 – 10/7
Trochanteric Bursitis
Trauma or Unaccustomed exercise, also in Inflammatory Arthritis
o Worse on walking up the stairs; Tender to lie on
o Exercise, Steroid Injection although poor evidence base; Surgery often necessary
o Gluteus Medius Tendonopathy at Insertion into trochanter can cause similar
syndrome, but does not respond to injection; Demonstrated on MRI
Sacroiliac Joint Dysfunction
Caused by abnormal motion of SIJ; Presents with LBP, Buttock,
Sciatic Leg, Groin and Hip pain; Bending, Stairs and Rising from seat can provoke
o Hypermobility – Typically, Extra-articular due to weakened, injured or sprained
ligaments; Joint degeneration occurs over time
o Post-pregnancy Pelvic Joint pain believed to be due to stretched out ligaments (due
to Relaxin) failing to return to normal tautness
o Hypomobility – Locks due to wearing down with age or OA; Also, can occur with
Ankylosing Spondylitis or RA
o Treatment with Rest, Ice/Head, NSAIDs, Corticosteroid Injections (If benefit reported,
confirms the diagnosis); Surgical fixation of SIJ
Meniscal Injury
• Menisci are partially attached Fibrocartilages that stabilise the Femoral Condyles on the flat
Tibial Plateaux; Resilient to injury but more vulnerable with age
o Torn by injury, commonly in sports which involve twisting and bending
o Immediate Medial or Lateral Knee Pain and Swelling within hours; Affected side is
tender; The Knee might lock flexed if large tear
• Immediate treatment to apply Ice Compress; MRI will demonstrate the tear
• Early Arthroscopic repair or Trimming of torn meniscus is essentially, especially in active
sportspeople; Reduces Recurrent pain, Swelling and Locking but not risk of Secondary OA
• Post-op Quadriceps exercises aid return to sport and activity
• Clinically examined with Apley’s Grind Test
Cruciate Ligament Injury
• ACL resists Anterior Translation and Medial Rotation of Tibia
on Femur, while PCL resists Posterior Translation and Lateral
Rotation of Tibia on Femur
• Torn Cruciate accounts for around 70% of Haemarthrosis in
young people; Often co-exists with Meniscal tears; Clinically
examined with Anterior Draw Test, Posterior Sag
• MRI is investigation of choice; Requires urgent Orthopaedic
referral, with reconstructive surgery necessary; Significant
incidence of Secondary OA
Collateral Ligament Injury
• Medial Ligament more commonly affected than Lateral; Pain typically at insertion into Upper
Medial Tibia, worsened by standing or stressing (Varus and Valgus stress at 0 and 30deg)
• Physiotherapy and Local Corticosteroid Injection
OSTEOCHONDROSIS
• Focal disturbance of the Ossification Centre of the ends of bones
• Osgood-Schlatter Disease – Localised pain and Swelling, over Tibial
Tubercle or Patella Tendon Insertion; Usually athletic teens;
Responds to local treatment and changes in sports
• Sever’s Disease – Osteochondritis of Achilles insertion into Calcaneus
PATELLOFEMORAL PAIN SYNDROME
• Knee pain ranging from Mild to Severe Discomfort, seeming originating from Posterior surface
of Patella and Femur; Excluding Intra-articular and Peri-Patellar Pathology
• Runners, Cyclists, Basketball players; Thought to be due to increased pressure on joint
• Discomfort worsened by sitting with bent knees or descending stairs
• Managed with Exercise therapy, NSAIDs, Rest; Surgery only in extreme cases
Chondromalacia Patellae
Patellar Articular Cartilage Softening; Fibrillated Retropatellar Cartilage seen on Arthroscopy
o Patellar Misalignment, or Recurrent Dislocation (Typically, Adolescent girls) = Surgery
ILIOTIBIAL BAND SYNDROME
• Common injury to knee associated with Running, Cycling, Hiking and Weight-
lifting; Range from stinging sensation superolateral to knee joint, to Swelling
and Thickening of IT band
o Most commonly pain felt during foot strike, and might persist
• Can result from Abnormal leg or feet anatomy, Unaccustomed exercise, or
abnormal loading, for example, “toeing in” while cycling
• Manage with RICE followed by stretching; Muscle strengthening of Gluteus and Medial Quadriceps by Exercise therapy
CONDITIONS OF THE SHOULDER
Shoulder is a shallow joint with large ROM; Humeral head held by Rotator cuff (Supraspinatus, Infraspinatus, Teres Minor, Subscapularis) which is part of the joint capsule
o Rotator cuff, especially Supraspinatus, prevents Humeral head blocking against the Acromion during Abduction; Deltoid pulls up, Supraspinatus pulls in, allowing for turning movement; Greater Tuberosity glides under Acromion without impingement
Rotator Cuff (Supraspinatus) Tendonosis (=Impingement Syndrome)
• Common cause of shoulder pain in all ages; Follows trauma in 30%, Bilateral in <5%
• Pain radiates to Upper arm, made worse by Arm Abduction and Elevation; Worst during
middle of Abduction range (‘Painful arc’)
• Painful spasm of Trapezius can occur; Passive elevation reduces impingement
• Might have associated Subacromial Bursitis; Isolated Bursitis can occur in direct trauma, such
as Falling-on-outstretched Arm or Elbow; Acromioclavicular Osteophytes increase the risk of
impingement, might require surgical removal
• Treatment with Analgesia, NSAIDs and PT; Severe pain response to US-guided Injection of
Corticosteroids into Subacromial Bursa; 10% with develop worse pain 24-48hrs after injection
o 70% will improve and self-mobilise; PT reduces Persistent Stiffness
Rotator Cuff Tear
• Caused by trauma but also spontaneously in Elderly and Rheumatoid Arthritis
• Prevents Active Abduction of arm; Initiation of elevation assisted by other arm; Deltoid
muscle can hold in place once elevated
• Surgical tear repair in younger people; Not always possible in Elderly or RA