Orthopedic Anesthesia Flashcards
(179 cards)
What are the two biggest factors associated with development of osteoporosis?
- Elderly age
- Menopause
What hormonal changes are characteristic of osteoporosis?
- ↑ PTH
- ↓ Vit D
- ↓ HGH
- ↓ Insulin-like growth factors
What are the four most common meds used to treat osteoporosis?
dronate drugs
- Fosamax (Alendronate)
- Actonel (Risedronate)
- Boniva (Ibandronic Acid)
- Reclast (Zoledronate)
meds that ↑ bone density, prevent post-menopausal osteoporosis
What 5 fractures are common in pts w/ osteoporosis?
- stress fractures
- compression fx of thoracic/lumbar spine
- proximal femur fx
- proximal humerus fx
- wrist fx
Osteoarthritis is the loss of ________ ________.
Articular Cartilage - bone on bone
leads to inflammation
What are 6 symptoms of Osteoarthritis?
- pain
- crepitance
- decreased mobility
- joint deformity
- Herberden Nodes
- Bouchard Nodes
Differentiate between Bouchard’s nodes and Heberden’s nodes.
- Bouchard’s = proximal interphalangeal joints
- Heberden’s = distal interphalangeal joints
What 6 meds are typically used for OA management?
- NSAIDs: Meloxicam
- Opioids
- COX-2 inhibitors: Celebrex
- Topical Voltaren
- Intra-articular steroids
- Chondroprotective agents: Glucosamine, Chondroitin
What is a risk factor w/ Voltaren being absorbed systemically?
Peptic ulcer disease
What drug is the most common chondroprotective agent that helps protect the articular joint?
Glucosamine
What anesthetic considerations should be given to glucosamine?
Glucosamine needs to be stopped two weeks prior to surgery due to PLT aggregation inhibition.
Arthritis characterized by morning stiffness that improves throughout the day is….
Rheumatoid arthritis
Arthritis that is characterized by worsening symptoms throughout the course of the day is…
Osteoarthritis
Rheumatoid Arthritis is a ________ and ________ inflammatory disease.
Chronic & Systemic
What is RA characterized by?
joint synovial tissue/connective tissue inflammation
* bone erosion
* cartilage destruction
* impaired joint integrity
What are 5 symptoms of RA?
- pain & stiffness
- anorexia
- fatigue
- weakness
- subcutaneous nodules around joints, extensor surfaces, and bony prominences
What labs are typically elevated in a patient with rheumatoid arthritis?
- ↑ Rheumatoid factor (RF)
- ↑ Anti-immunoglobulin antibody
- ↑ C-reactive protein (CRP)
- ↑ Erythrocyte Sedimentation Rate (ESR)
What common dose of stress dose glucocorticoid is used for RA patients?
50mg hydrocortisone (Solu-cortef)
What two TNFα inhibitors are commonly used to treat RA?
- Infliximab
- Etanercept
Which of the following drugs treat RA?
- Methotrexate
- Hydroxychloroquine
- Sulfasalazine
- Leflunomide
Trick question. All of them do
- Methotrexate: antimetabolite
- Hydroxychloroquine: antimalarial/antirheumatic
- Sulfasalazine: anti-inflammatory
- Leflunomide: disease modifying antirheumatic drugs (DMARDs)
What airway concerns should be considered with RA patients?
- Limited TMJ movement
- Narrowed glottic opening
- Cricoarytenoid arthritis
Where is the most instability typically located in the cervical spine of RA patients?
Atlantoaxial Junction
(be careful not to displace the odontoid process and impinge on the c-spine or vertebral arteries)
What are the signs and symptoms of atlantoaxial subluxation?
- Headache
- Neck pain
- Extremity paresthesias (especially with movement)
- Bowel/bladder dysfunction
What airway management techniques can be used when there is concern for atlantoaxial subluxation?
- video laryngoscopy
- manual in-line stabilization
- awake fiberoptic