What are the two biggest factors associated with development of osteoporosis?
What hormonal changes are characteristic of osteoporosis?
What are the four most common meds used to treat osteoporosis?
dronate drugs
- Fosamax (Alendronate)
- Actonel (Risedronate)
- Boniva (Ibandronic Acid)
- Reclast (Zoledronate)
meds that ↑ bone density, prevent post-menopausal osteoporosis
What 5 fractures are common in pts w/ osteoporosis?
Osteoarthritis is the loss of ________ ________.
Articular Cartilage - bone on bone
leads to inflammation
What are 6 symptoms of Osteoarthritis?
Differentiate between Bouchard’s nodes and Heberden’s nodes.
What 6 meds are typically used for OA management?
What is a risk factor w/ Voltaren being absorbed systemically?
Peptic ulcer disease
What drug is the most common chondroprotective agent that helps protect the articular joint?
Glucosamine
What anesthetic considerations should be given to glucosamine?
Glucosamine needs to be stopped two weeks prior to surgery due to PLT aggregation inhibition.
Arthritis characterized by morning stiffness that improves throughout the day is….
Rheumatoid arthritis
Arthritis that is characterized by worsening symptoms throughout the course of the day is…
Osteoarthritis
Rheumatoid Arthritis is a ________ and ________ inflammatory disease.
Chronic & Systemic
What is RA characterized by?
joint synovial tissue/connective tissue inflammation
* bone erosion
* cartilage destruction
* impaired joint integrity
What are 5 symptoms of RA?
What labs are typically elevated in a patient with rheumatoid arthritis?
What common dose of stress dose glucocorticoid is used for RA patients?
50mg hydrocortisone (Solu-cortef)
What two TNFα inhibitors are commonly used to treat RA?
Which of the following drugs treat RA?
- Methotrexate
- Hydroxychloroquine
- Sulfasalazine
- Leflunomide
Trick question. All of them do
- Methotrexate: antimetabolite
- Hydroxychloroquine: antimalarial/antirheumatic
- Sulfasalazine: anti-inflammatory
- Leflunomide: disease modifying antirheumatic drugs (DMARDs)
What airway concerns should be considered with RA patients?
Where is the most instability typically located in the cervical spine of RA patients?
Atlantoaxial Junction
(be careful not to displace the odontoid process and impinge on the c-spine or vertebral arteries)
What are the signs and symptoms of atlantoaxial subluxation?
What airway management techniques can be used when there is concern for atlantoaxial subluxation?