Orthopedics Flashcards
(123 cards)
Bone cement
- polymethylmethacrylate (MMA) cement fills in gaps in bone and binds firmly to prosthetic device
Signs and symptoms of Bone cement implantation syndrome
- hypoxia (due to increased pulmonary shunt)
- hypotension
- dysrhythmias (heart block and sinus arrest)
- pulmonary HTN (due to increased PVR)
- decreased cardiac output
** When is embolization most frequent during orthopedic surgery?
- prosthetic insertion
How do you minimize the effects of bone cement (MMA)?
- increase inspired O2 prior to MMA
- maintain euvolemia
- vasopressor PRN
- Surgical methods (vent distal femur, high pressure lavage of femoral shaft)
What type of reaction causes bone cement to harden?
- exothermic reaction.
Complications associated with bone cement
- embolization of fat, bone marrow, cement and air into femoral venous channels
- residual MMA monomer produces vasodilation and decreases SVR
- tissue thromboplastin release may cause platelet aggregation, microthrombus into lungs and CV instability
Pneumatic tourniquets
- used on upper and lower extremities to create bloodless field and minimize blood loss.
What 7 problems are associated with pneumatic tourniquets?
- hemodynamic changes
- pain
- metabolic changes
- arterial thromboembolism
- pulmonary embolism
- muscle and nerve injury
- limb cooling
What hemodynamic changes are associated with pneumatic tourniquets?
- exsanguination of limb shifts blood volume to central circulation
- cuff inflation: decreased core temperature, increased HR
- prolonged cuff inflation (45-60 minutes): HTN, tachycardia, sympathetic stimulation, sweating
- cuff deflation: decreased CVP, decreased MAP
Tourniquet pain
- severe aching and burning after several minutes
- supplemental analgesia required
- ** slow conduction C-fibers are most affected
- pain less common if regional anesthesia is used
Metabolic changes associated with tourniquets
- metabolic waste products accumulate in the tissue
- cuff deflation causes rapid wash out of waste products
- increased PaCO2, etCO2, serum lactate, potassium
- increased minute volume in spontaneous breathing patients
- dysrhythmias
- reperfusion injuries from free radical formation
What cuff pressures should you use to inflate a tourniquet?
- typically cuff pressure is 100 torr above systolic pressure
- upper extremity: 250 torr
- lower extremity: 350 torr
Why does having the tourniquet inflated cause metabolic changes?
- extremity switches to anaerobic metabolism
- vasculature in the extremity will vasodilate
When is a tourniquet contraindicated?
- in an extremity with calcified arteries
Tourniquet ischemia, especially of the lower extremity, can lead to ____________
- deep venous thrombosis
Muscle and nerve injury associated with tourniquet use
- prolonged inflation (> 2 hours) can cause transient muscular injury, permanent nerve injury and rhabdomylosis
Who is responsible for monitoring tourniquet time?
- anesthetist
Fat embolism syndrome - triad of symptoms
- dyspnea
- confusion
- petechiae (chest, upper extremities, axillary and conjunctiva).
What is the classic timeframe for presentation of fat embolism syndrome?
- within 72 hours of long bone or pelvic fracture
What types of injuries and procedures are associated with fat embolism syndrome?
- long bone fractures
- CPR
- liposuction
- IV lipids
Fat embolism syndrome is ___________ and ____________.
- less frequent
- more fatal (10-20%)
Fat embolism syndrome - pathophysiology
- fat globules are released by disrupted fat cells in fractured bone and enter circulation through tears in medullary vessel
- increased fatty acid levels are toxic to capillary-alveolar membrane
- causes release of vasoactive amines and prostaglandins
- progresses to ARDS, cerebral capillary damage, edema
What 2 coagulation abnormalities are associated with fat embolism syndrome?
- thrombocytopenia
- prolonged clothing times
What changes will you see in a patient with fat embolism syndrome who is under general anesthesia?
- decline in etCO2 and SpO2
- increase in pulmonary artery pressure