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PHM702 > Osteoarthritis > Flashcards

Osteoarthritis Flashcards

1
Q

OA - Risk Factors

A

obesity
female gender
occupations involving mechanical stress
certain sports
joint injury or surgery
genetic predisposition

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2
Q

OA - Signs

A

asymmetrical involvement
local tenderness
limited motion with movement
synovitis

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3
Q

OA - Symptoms

A

deep, aching pain
stiffness
weather-related onset
limited joint motion

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4
Q

OA - Common Sites

A

hands
hips
knees
feet
spine

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5
Q

OA - Diagnosis

A

history
physical exam
radiographic findings

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6
Q

OA - Non-Pharmacological Interventions

A

exercise
weight loss
Tai Chi
cane
knee brace

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7
Q

OA - First-Line Drug Class

A

Oral NSAIDs

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8
Q

Topical NSAIDs - Indications

A

knee - strong recommendation
hand - conditional recommendation

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9
Q

Intra-Articular Steroids - Indications

A

knee & hip - strong recommendation
hand - conditional recommendation

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10
Q

Intra-Articular Steroids - Relative CIs

A

SSTI
suspected joint infection
unstable coagulopathy
uncontrolled DM
broken skin at injection site

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11
Q

Intra-Articular Steroids - Frequency of Administration

A

no more than every 3 months

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12
Q

Intra-Articular Steroids - Onset & Duration of Action

A

2-3 days
4-8 weeks

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13
Q

Acetaminophen - Indications

A

conditional recommendation in knee, hip, and hand

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14
Q

Tramadol - Indications and Place in Therapy

A

conditional recommendation in knee, hip, and hand

failed Tx with APAP / topical NSAIDs
CIs to PO NSAIDs / IA steroids

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15
Q

Duloxetine - Indications

A

conditional recommendation in knee, hip, and hand

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16
Q

Duloxetine - Onset of Action

A

4 weeks

17
Q

Duloxetine - Dose

A

60 mg PO QD

18
Q

Topical Capsaicin - Indication

A

knee - conditional recommendation
hand - conditional recommendation AGAINST

19
Q

OA - Treatment Recommended Against

A

bisphosphonates
glucosamine
hydroxychloroquine
methotrexate
TNF inhibitors
chondroitin (knee & hip only)

PHM702 (20 decks)

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