Osteoarthritis

Question 1

What is oesteoarthritis?

Answer 1

Clinical syndrome of joint pain acompanied by varying degrees of functional limitation & reduced QOL

Question 2

What is the pathophysiology of osteoarthritis?

Answer 2

• Rate of dmg exceeds rate of repair
• Joint fails to dissipate load
• Leads to cycle degredation.
• Exposed bone marrow -> mor dmg
• Further loss of cartilage & growth of osteophytes
• Narrowing of joint space
• Results in synovitis & effusion

Question 3

What are the signs and symptoms of osteoarthritis?

Answer 3

Acitivity related joint pain
Morning stiffness lasts no longer that 30mins
Muscle wasting
Hands/fingers have nodules present.

Question 4

What the diagnosis of osteoarthritis clinically without investigations?

Answer 4

Activity relates joint pain AND
morning stiffness lasts no longer tha 30 mins AND
over 45 yrs old.

Question 5

What lifestlye changes can you do to help manage osteoarthritis?

Answer 5

Weight loss
Exercise - core
Physical aids

Question 6

What pharmacological treatments can you use for osteoarthritis?

Answer 6

Topical NDSAIDs / Topical Capsacin
Paracetamol
Oral NSAIDs + PPI
Opoids
Intra-articular CC