Osteogenesis Imperfecta

Question 1

Osteogenesis imperfecta is the most common osteoporosis syndrome in children. True or False?

Answer 1

TRUE.

OI is the most common osteogenesis syndrome in children.

((osteogenesis imperfecta is a genetic syndrome- so children would get it from parents))

Question 2

Does the severity of OI differ from case to case?

Answer 2

YES.

OI has 4 different types, all differing in severity.

Question 3

What are some s/s of osteogensis imperfecta?

Answer 3

-fractures, obviously
-bone deformity
-bone fragility
-HEARING LOSS- due to there being bones in your ears that help with sound and vibration !!
-dental deformities (dentinogenesis imperfecta)
-blue sclera is also possible due to the simultaneous thinning of collagen in the eye with OI

Question 4

What type of drug is usually prescribed to a patient with OI and why?

Answer 4

Bisphosphonates are likely to be prescribed to OI patients because biphosphonates work to slow the thinning of bones.