Osteoporosis drugs Flashcards
(5 cards)
1
Q
Administration of bisphosphonates
A
- For 5 years
- To prevent GI effects - take first thing in morning/on empty stomach, remain upright for 30 min after
- To maximise PO absorption - avoid food, drink and drugs before and after
2
Q
AEs of bisphosphonates
A
GI disturbance - abdominal pain, nausea, dyspepsia, constipation, diarrhoea, oesophagitis, gastritis
Atypical femoral fractures
Jaw osteonecrosis
3
Q
AEs of denosumab
A
MSK pain
Eczema
Hypercholesterolaemia
4
Q
AEs of teriparatide
A
Osteosarcoma
5
Q
AEs of strontium ranelate
A
AMI