Other respiratory Flashcards

(41 cards)

1
Q

In what pH range are people likely to benefit from NIV?

A

7.25-7.35

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2
Q

What is a blood contraindication for chest drain insertion?

A

INR >1.3

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3
Q

What can worsen a tension pneumothorax?

A

ventilation through endotracheal tube

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4
Q

NRT (ADR, use)

A
  • nausea and vomiting, headaches and flu-like symptoms

- nicotine patches + another form of NRT e.g. gum, inhalator, nasal spray) if high level of dependence

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5
Q

Varenicline (MOA, ADR, CONTRA)

A
  • nicotinic receptor partial agonist
  • more effective than bupropion
  • ADR: nausea, insomnia, headache, abnormal dreams
  • caution if depression or self harm
  • CONTRA in breast feeding and pregnancy
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6
Q

Bupropion (MOA, ADR, CONTRA)

A
  • norepinephrine and dopamine reuptake inhibitor, nicotinic antagonist
  • small risk of seizures
  • CONTRA: epilepsy, pregnancy and breast feeding
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7
Q

Smoking cessation in pregnancy:

A
  • CBT

- NRT if failure

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8
Q

When should oxygen therapy be administered:

A
  • critically ill (anaphylaxis, shock etc)

- reservoir mask 15L/min

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9
Q

Oxygen target sats in oxygen therapy:

A
  • acutely ill: 94-98%
  • patients at risk of hypercapnia (e.g. COPD): 88-92%
  • reduce in stable patients with satisfactory sats
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10
Q

Oxygen therapy in COPD patients:

A
  • prior to blood gases, 28% venturi mask at 4L/min and aim for 88-92%
  • with risk factors for hypercapnia and no Hx of respiratory acidosis
  • adjust range to 94-98% if pCO2 normal
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11
Q

Situations where oxygen therapy should not be routinely used if no evidence of hypoxia:

A
  • MI or ACS
  • stroke
  • obstetric emergencies
  • anxiety-related hyperventilation
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12
Q

Common causes of lobar collapse:

A
  • lung cancer
  • asthma (mucous plugging)
  • foreign body
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13
Q

CXR signs of lobar collapse:

A
  • tracheal deviation towards
  • mediastinal shift towards
  • elevation of hemidiaphragm
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14
Q

Causes of obstructive lung disease:

A
  • asthma
  • COPD
  • bronchiectasis
  • bronchiolitis obliterans
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15
Q

Causes of restrictive lung disease:

A
  • pulmonary fibrosis
  • asbestosis
  • sarcoidosis
  • ARDS
  • infant RDS
  • kyphoscoliosis e.g. ankylosing spondylitis
  • neuromuscular disorders
  • severe obesity
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16
Q

Respiratory manifestations of RA:

A
  • pulmonary fibrosis
  • pleural effusion
  • pulmonary nodules
  • bronchiolitis obliterans
  • complications of drug therapy e.g. methotrexate pneumonitis
  • pleurisy
  • Caplan’s syndrome - massive fibrotic nodules with occupational coal dust exposure
  • infection secondary to immunosuppression
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17
Q

Key indications NIV:

A
  • COPD with respiratory acidosis pH 7.25-7.35
  • type II RF secondary to chest wall deformity, neuromuscular disease or OSA
  • cardiogenic pulmonary oedema unresponsive to CPAP
  • weaning from tracheal intubation
18
Q

Kartagener’s

A
  • primary ciliary dyskinesia
  • dextrocardia/complete situs inversus (quiet heart sounds, small volume complexes in lateral leads)
  • bronchiectasis
  • recurrent sinusitis
  • subfertility (diminished sperm motility and defective ciliary action in fallopian tubes)
19
Q

Contraindications to chest drain insertion:

A
  • INR >1.3
  • platelet count <75
  • pulmonary bullae
  • pleural adhesions
20
Q

Where should a chest drain be inserted?

A

5th intercostal space in midaxillary line

21
Q

Complications of chest drain insertion:

A
  • failure of insertion
  • bleeding
  • infection
  • penetration of lung
  • re-expansion pulmonary oedema
22
Q

What is re-expansion oedema:

A
  • preceded by onset of cough or SOB

- avoid by clamping tube regularly in event of rapid fluid output (should not exceed 1 L over less than 6 hours)

23
Q

How can you confirm the position of the chest tube?

A
  • aspiration of fluid from drainage tube

- swinging of fluid within drain tubing when patient inspires and on XR

24
Q

Examples of extrinsic allergic alveolitis:

A
  • bird fancier’s lung
  • farmer lung
  • malt workers’ lung: aspergillum clavatus
  • mushroom worker’s lung: thermophilic actinomycetes
25
Investigation of extrinsic allergic alveolitis:
- imaging: upper/mid zone fibrosis - bronchoalveolar lavage: lymphocytosis - serological assays for specific gig antibodies - blood: NO eosinophilia
26
Management of extrinsic allergic alveolitis:
- avoid precipitating factors | - oral glucocorticoids
27
Causes of haemoptysis:
- lung cancer - pulmonary oedema: bibasal crackles and S3 - TB - PE - LRTI - bronchiectasis - mitral stenosis: mala flush, mid-diastolic murmur - aspergilloma: history of TB, rounded opacity - granulomatosis with polyangiitis - Goodpasture's
28
Investigation of mesothelioma:
- CXR shows pleural effusion or pleural thickening - pleural CT - pleural effusion - send for biochem and cytology - LA thoracoscopy
29
Prevention and treatment of acute mountain sickness:
- gain altitude no more than 500m per day - acetazolamide (carbonic anhydrase inhibitor) to prevent - descend
30
Management of high altitude pulmonary oedema:
- descend - nifedipine, dexamethasone, acetazolamide, phosphodiesterase, type V inhibitors - oxygen
31
Management of high altitude cerebral oedema?
- descend | - dexamethasone
32
Causes of raised TLCO:
- asthma - pulmonary haemorrhage - left to right cardiac shunts - polycythaemia - hyperkinetic states - male gender, exercise
33
Cause of decreased TLCO:
- pulmonary fibrosis - pneumonia - pulmonary emboli - pulmonary oedema - emphysema - anaemia - low cardiac output
34
Increased KCO with normal or reduced TLCO:
- pneumonectomy/lobectomy - scoliosis/kyphosis - neuromuscular weakness - ankylosis of costovertebral joints
35
Superior vena cava syndrome
- can present with lung cancer - distended veins - also lymphoma, sarcoidosis and aortic aneurysm
36
Is it safe to continue prednisolone in pregnancy?
yes
37
Conditions causing a cavitating lung lesion in CXR:
- abscess - squamous cell lung cancer - TB - Wegener's - PE - RA - aspergillosis, histoplasmosis, coccidioidomycosis
38
Pulmonary oedema signs on CXR:
- interstitial oedema - bat's wing appearance - upper lobe diversion (increased blood flow to superior part) - Kerley B lines - expansion of interstitial space by fluid - pleural effusion - cardiomegaly if cardiogenic cause
39
Causes of mediastinal widening on CXR:
- vascular problems: thoracic aortic aneurysm - lymphoma - retrosternal goitre - teratoma - tumours of thymus
40
Signs of lobar collapse on CXR:
- tracheal deviation towards - mediastinal shift towards - elevation hemidiaphragm
41
Empyema aspirate:
pH <7.2 low glucose high LDH