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Gyn-Onc/Surgery > Ovarian Cancer Facts > Flashcards

Ovarian Cancer Facts Flashcards

(60 cards)

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1
Q

Covers 80-85% of all ovarian tumors; age at diagnosis usually older than 40 years

A

Coelemic epithelial

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2
Q

Tumors includes in coelemic epithelial tumors

A

Serous, mucinous, endometrioid, clear cell, brenner

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3
Q

Histogenesis of serous tumors

A

Ciliated tubal epithelium

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4
Q

Histogenesis of mucinous tumors

A

Columnar endocervical epithelium

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5
Q

Histogenesis of endometrioid tumors

A

Endometrial glands

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6
Q

Histogenesis of clear cell tumors

A

Mesonephric tissue

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7
Q

Histogenesis of brenner tumor

A

Transitional urothelium

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8
Q

What are the unique findings of serous tumors and what is the tumor marker?

A

Psamomma bodies

Tumor marker = CA -125

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9
Q

What are the unique findings of mucinous tumors

A

Pseudomyoxoma peritonei

Tumor marker = CEA

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10
Q

What is the tumor marker for endometrioid tumor?

A

CA-125

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11
Q

What is the tumor marker for clear cell tumors?

A

CA-125

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12
Q

What is the unique findings for brenner tumors?

A

Walthard cell rests

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13
Q

What is the percent malignancy of serous tumors?

A

20%

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14
Q

What is the percent malignancy of mucinous tumors?

A

15%

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15
Q

What is the percent malignancy of Endometrioid tumors?

A

95%

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16
Q

What is the percent malignancy of Clear cell tumors?

A

98%

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17
Q

What is the percent malignancy of Brenner tumor?

A

2%

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18
Q

Covers 10-15% of all ovarian tumors; age at diagnosis is usually younger than 30y/o

A

Germ cell tumor

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19
Q

Tumors included in germ cell tumors

A

Teratoma (immature and mature)

Dysgerminoma

Gonadoblastma

Endodermal sinus (“yolk sac tumor”)

Embryonal carcinoma

Non-gestational choriocarcinoma

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20
Q

Histogenesis of immature teratoma

A

Fetal embryonic tissue

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21
Q

Histogenesis of mature teratoma

A

Many mature cell types

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22
Q

Histogenesis of dysgerminoma

A

Primitive germ cells

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23
Q

Histogenesis of dysgerminoma

A

Primitive germ cells

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24
Q

Histogenesis of gonadoblastoma

A

Dysgenetic gonads with Y chromosomes

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25
Histogenesis of endodermal sinus (“yolk sac tumor”)
Extraembyonic tissue
26
Histogenesis of embryonal carcinoma
Embryonic tissue
27
Histogenesis of non-gestational choriocarcinoma
Extraembryonic tissue
28
Tumor markers of immature teratoma
AFP and CA-125
29
Unique findings of Mature teratoma
Rokitansky prominence
30
Tumor marker for dysgerminoma
LDH
31
Unique findings of endodermal sinus “yolk sac tumor”
Schiller Duvall bodies
32
Tumor markers of embryonal carcinoma
AFP Beta-hCG
33
Tumor markers of endodermal sinus “yolk sac tumor”
AFP
34
Tumor markers of non-gestational choriocarcinoma
Beta-hCG
35
% malignant of immature teratoma
100%
36
% malignant of mature teratoma
0-1%
37
% malignant of Dysgerminoma
100%
38
% malignant of Gonadoblastoma
0%
39
% malignant of Endodermal sinus “yolk sac tumor”
100%
40
% malignant of Embryonal carcinoma
100%
41
% malignant of Non-gestational choriocarinoma
100%
42
Covers 3-5% of all ovarian tumors; age at diagnosis is usually around 50yrs with a range of 20-80
Gonado-stromal
43
Histogenesis of granulosa cell tumors
Ovarian gonadal cells
44
Histogenesis of fibroma
Thecoma elements
45
Histogenesis of thecoma
Thecoma elements
46
Histogenesis of steroli-leydig tumor
Testicular gonadal cells
47
Histogenesis of lipid cell tumor
Gonadal stromatolites cells
48
Histogenesis of gynandroblastoma
Both ovarian and testicular cells
49
Unique findings of granulosa cell tumors
Cal-Exner bodies Estrogen production Inhibin
50
Unique findings of Fibroma
Seen w Meig’s syndrome
51
Unique findings of Thecoma
Estrogen production
52
Unique findings of Serotonin-leydig
Crystals of Reinke Testosterone production
52
Unique findings of Serotonin-leydig
Crystals of Reinke Testosterone production
53
Unique findings of Gynandroblastoma
Testosterone production
54
% malignancy of granulosa cell tumor
<5%
55
% malignancy of Fibroma
<5%
56
% malignancy of Thecoma tumor
<5%
57
% malignancy of Seroti-leydig tumor
<5%
58
% malignancy of Lipid cell
30%
59
% malignancy of Gynandroblastoma
100%

Gyn-Onc/Surgery (11 decks)

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