Overview Flashcards

(32 cards)

1
Q

Circadian Rhythms

A

Biological rhythms that last “about a day”. (Are usually >24 hours, due to the need to reset and adjust to fit the 24 hour rotation of the Earth, hence why zeitgebers are important)

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2
Q

Diurnal

A

Active during the day (light periods)

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3
Q

Zeitgebers

A

(German: “time giver”) - cues from the environment used to entrain an animal’s circadian rhythm
(sunlight is the most effective zeitgeber for humans)

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4
Q

Entrainment

A

The process of synchronizing one’s biological rhythm to a cue in the environment.
An example would be adjusting how much you sleep.

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5
Q

When lighting is constant however (no night), the hamster goes to sleep and wakes up at ____

A

Roughly the same time so circadian behavior is influenced by light/dark, but not totally.
Demonstrates free-running rhythms

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6
Q

Suprachiasmic nucleus (SCN)

A

The brain has a biological clock with 24-hour periodicity, the _____

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7
Q

The SCN releases chemicals that affect

A
  • Lower body temperature
  • Lower blood pressure
  • Digestion
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8
Q

We stick to circadian rhythms because of the internal biological clock, known as the _____ and external cues, known as

A

Suprachiasmic nucleus (SCN); zeitgebers

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9
Q

The _____ send messages to the SCN to tell when it’s light or when it is dark.

A

Optic nerves

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10
Q

Photopigment within certain retinal ganglion cells that project to the SCN. Does not mediate vision, but tells SCN whether it is light or dark.
Not for vision but for entrainment.

A

Melanopsin

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11
Q

When it is light, melanopsin containing retinal ganglia ____ hormone release by the SCN

A

Inhibit

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12
Q

When it is dark, melanopsin containing retinal ganglia set-off a chain reaction, ultimately causing the Pineal gland to release a hormone called _____

A

Melatonin

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13
Q

Brain recording using _____ enables researchers to observe the brain’s behavior/activity, even without the participant having to be awake

A

Electroencephalogram (EEG)

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14
Q

There are 4 distinctive stages of sleep, and one additional type of sleep that occurs during stage 1, called ______ sleep.

A

Rapid Eye Movement (REM)

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15
Q

Awake/alert

A
  • fast (13-30 Hz, beta)
  • low amplitude EEG waves
  • very small and fast
  • beta has the smallest peaks
  • decent amount of mental activity
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16
Q

Eyes closed, relaxed

A
  • slower (8-13 Hz, alpha)
  • higher amplitude EEG waves
17
Q

Stage 1

A

Stage ___ has even slower (4-8 Hz, theta), low amplitude EEG waves

18
Q

Stage 2

A

Stage ___ is where EEG looks like stage 1, punctuated by K-complexes and sleep spindles

19
Q

Stages 3 & 4

A

Stage _ & _ have slow-wave sleep (SWS) characterized by predominantly high amplitude delta (1-4 Hz) rhythms

20
Q

Non-REM (NREM)

A
  • Initial stage 1 and stages 2-4 without REM are called _____. The EEG during REM sleep looks like the EEG during wakefulness.
21
Q

Down-states; theta and delta

A

Stage 2 K-complexes reflect neuronal __ and lead to ___ and ___ waves in slow-wave sleep (SWS) in stages 3 and 4

22
Q

Postsynaptic potentials (PSPs)

A

Neurons like to have resting _____ that are either “up” (slightly depolarized, ready for action potential) or “down” (slightly hyperpolarized, silent and not ready to fire an action potential)

23
Q

Thalamus

A

When cortical neurons are in “down-states”, they are less receptive to input from the _____. In other words, these down-states inhibit sensory input/arousal.

24
Q

Motor pathways

A

Most are inhibited during REM to prevent a person from acting out his or her dreams (therefore sleepwalking or sleep talking cannot occur during REM)

25
Paradoxical sleep
REM is sometimes called a paradox because its EEg looks like wakefulness. Brain (EEG) and eye (EOG) activity of awake person and REM sleeper look almost identical.
26
REM sleep
Dreaming is not necessarily equated to REM sleep, although >80% dreaming takes place in REM dreams: emotional, illogical, sudden shifts in plots. - Non-REM dreams: shorter, commonplace themes
27
Insomnia
20+ minutes to fall asleep - Waking too early - Not being able to fall back asleep if woken in middle of the night
28
Melatonin, Depressant drugs (Benzodiazepines --> Valium, Xanax), Non-benzos (e.g., Ambien), alcohol)
Insomnia is treated by pharmacological treatments like _____
29
Cataplexy
Sudden loss of muscle tone (despite being fully conscious)
30
Orexin
____ neurons in the hypothalamus serve as a sleep/wake "switch". Project to other sleep-related brain regions. Keeps sleep "at bay", prevent rapid progression from wakefulness to REM sleep
31
Hypothalamic orexin neurons
Symptoms of narcolepsy often co-occur with degeneration of _____
32
Narcolepsy
_____ may be treated with stimulant drugs (e.g., amphetamine), caffeine, or modafinil (e.g., Provigil)